Results 31 to 40 of about 2,322,244 (160)

Mitochondrial proteomic analysis of ecdysterone protection against oxidative damage in human lens epithelial cells

International Journal of Ophthalmology, 2014
AIM:To investigate the protective effects of the natural medicinal monomer ecdysterone (ECR) with estrogenic activity against oxidative damage in human lens epithelial cells B3 (HLE-B3) caused by hydrogen peroxide 21(H2O2) and to pursue the possible ...
Chun-Yan Feng, Xiu-Rong Huang, Ming-Xin Qi, Song-Wen Tang, Sheng Chen, Yan-Hong Hu, Fa-Jie Ke, Xin Wang   +7 more
doaj   +1 more source

β‑ecdysterone protects against apoptosis by promoting autophagy in nucleus pulposus cells and ameliorates disc degeneration.

Molecular Medicine Reports, 2019
Increasing cell apoptosis is one of the major causes of intervertebral disc degeneration (IDD). β-ecdysterone has been demonstrated to protect PC12 cells against neurotoxicity.
Feng-ping Wen, Jun Yu, Cheng-jian He, Zhiwen Zhang, Aofei Yang   +4 more
semanticscholar   +1 more source

Analytical strategy for the detection of ecdysterone and its metabolites in vivo in uPA(+/+)‐SCID mice with humanized liver, human urine samples, and estimation of prevalence of its use in anti‐doping samples

Drug Testing and Analysis, 2021
Ecdysteroids are of interest as potential sport performance enhancers, due to their anabolic effects. The current study aimed to analyze levels of the most abundant ecdysteroid, ecdysterone (20‐hydroxyecdysone, 20‐OHE) in easily available dietary ...
S. Kraiem, M. Al-Jaber, Hana Al‐Mohammed, A. Al-Menhali, Noora Al-Thani, Murad Helaleh, W. Samsam, S. Touil, Alka Beotra, Costas Georgakopoulas, S. Bouabdallah, V. Mohamed-ali, M. Al Maadheed   +12 more
semanticscholar   +1 more source

The Mechanisms of Catalysis by Metallo β-Lactamases [PDF]

, 2008
Class B β-lactamases or metallo-β-lactamases (MBLs) require zinc ions to catalyse the hydrolysis of β-lactam antibiotics such as penicillins, cephalosporins, carbapenems, and cephamycins.
Michael I. Page, Page, Michael I., Badarau, Adriana, Adriana Badarau   +3 more
core   +1 more source

β-Ecdysterone Prevents LPS-Induced Osteoclastogenesis by Regulating NF-κB Pathway in Vitro

, 2020
BackgroundLipopolysaccharide (LPS), a bacteria product, plays an important role in orthopedic diseases. Drugs that inhibit LPS-induced osteoclastogenesis are urgently needed for the prevention of bone destruction.MethodsIn this study, we evaluated the ...
Y. Li, J. Zhang, C. Yan, Q. Chen, C. Xiang, Q. Zhang, X. Wang, J. k   +7 more
semanticscholar   +1 more source

Life table parameters of grape phylloxera treated by β-ecdysterone three lethal concentrations.

, 2016
Life table parameters of grape phylloxera treated by β-ecdysterone three lethal concentrations.
Khalid Hussain Dhiloo (771738), Hongtie Pu (3337263), Zhongyue Wang (771736), Junping Su (771737), Zongjiang Liu (3337260), Fuqian Yang (1625359), Yongqiang Liu (651861)   +6 more
core   +1 more source

Life history parameters of grape phylloxera treated by β-ecdysterone at three lethal concentrations.

, 2016
Life history parameters of grape phylloxera treated by β-ecdysterone at three lethal concentrations.
Khalid Hussain Dhiloo (771738), Hongtie Pu (3337263), Zhongyue Wang (771736), Junping Su (771737), Zongjiang Liu (3337260), Fuqian Yang (1625359), Yongqiang Liu (651861)   +6 more
core   +1 more source

β-ecdysterone from Cyanotis arachnoidea exerts hypoglycemic effects through activating IRS-1/Akt/GLUT4 and IRS-1/Akt/GLUT2 signal pathways in KK-Ay mice

, 2017
Our present study investigated the anti-diabetic activity and potential mechanism of β-ecdysterone (β-EC) derived from Cyanotis arachnoidea. In vitro, β-EC exhibited a promising effect on increasing GLUT4 translocation by 1.6 folds and glucose uptake by ...
Li Chen, Si-jian Zheng, Mi Huang, Xinhua Ma, Jie Yang, Shihao Deng, Yun Huang, Yanzhang Wen, Xinzhou Yang   +8 more
semanticscholar   +1 more source

Linear regression between morality (probit unit) of grape phylloxera and β-ecdysterone concentration (log-transformed).

, 2016
Linear regression between morality (probit unit) of grape phylloxera and β-ecdysterone concentration (log-transformed).
Khalid Hussain Dhiloo (771738), Hongtie Pu (3337263), Zhongyue Wang (771736), Junping Su (771737), Zongjiang Liu (3337260), Fuqian Yang (1625359), Yongqiang Liu (651861)   +6 more
core   +1 more source

Determination of Ecdysterone in Dietary Supplements and Spinach by Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry

, 2021
Ecdysterone is a naturally occurring steroid hormone of the ecdysteroid class. This group is widely marketed to athletes in dietary supplements as a “natural anabolic agent”, advertised to increase strength and muscle mass during resistance training ...
Krzysztof Grucza, Dorota Kwiatkowska, Aleksandra Drapała, Mariola Wicka   +3 more
core   +1 more source