Results 51 to 60 of about 2,322,244 (160)

β-Ecdysterone Attenuates Ang II-Induced Senescence in Human Aortic Smooth Muscle Cells via Autophagy Activation and ROS Suppression Through AKT/mTOR Pathway Inhibition.

open access: yesFrontiers in Bioscience
BACKGROUND This study aimed to elucidate the protective effects of β-ecdysterone (β-Ecd) against premature senescence in human aortic smooth muscle cells (HASMCs) and to unravel the underlying mechanisms.
Di Wu   +9 more
semanticscholar   +1 more source

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

open access: yesDrug Testing and Analysis, Volume 17, Issue 8, Page 1417-1442, August 2025.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis   +2 more
wiley   +1 more source

The Role of Sex Hormones in Cartilaginous Tissues: A Scoping Review

open access: yesJOR SPINE, Volume 8, Issue 2, June 2025.
The role of sex hormones within cartilaginous tissues remains poorly understood. To address this, we assembled and summarized the available literature regarding the effects of sex hormones in the intervertebral disc, temporomandibular joint, and articular cartilage.
Jeffrey L. Hutchinson   +3 more
wiley   +1 more source

Determination via an Integration Strategy of the Potential Dermal ECM Reconstruction Mechanism by Which the WAW Formula Alleviates Skin Aging

open access: yesJournal of Cosmetic Dermatology, Volume 24, Issue 4, April 2025.
ABSTRACT Background Traditional Chinese medicine (TCM) treats skin conditions and delays aging using specific formulas. TCM links skin health to internal organ functions: kidney qi deficiency accelerates aging, whereas spleen deficiency leads to dry, loose skin from insufficient qi and blood. The renowned spleen‐tonifying and kidney‐nourishing formula “
Yingying Lin   +6 more
wiley   +1 more source

Pharmacogenetics of ophthalmic topical β-blockers [PDF]

open access: yes, 2008
Glaucoma is the second leading cause of blindness worldwide. The primary glaucoma risk factor is elevated intraocular pressure. Topical β-blockers are affordable and widely used to lower intraocular pressure.
Smith, Edward M.   +4 more
core   +1 more source

Effects of Dietary Astaxanthin on Growth, Coloration, Immunity, and Antioxidant Capacity in Macrobrachium Rosenbergii

open access: yesAquaculture Nutrition, Volume 2025, Issue 1, 2025.
This study investigated the effects of astaxanthin (Ax) on the growth, body color, and immunity of Macrobrachium rosenbergii. Four different concentrations of Ax (0, 50, 100, and 200 mg kg−1) were supplemented in the basal diet to assess their impact on the growth, coloration, immunity, and antioxidant capacity in M. rosenbergii.
Huarong Li   +9 more
wiley   +1 more source

Mechanism of Jianpixiaoke Recipe in Treating Type 2 Diabetes Based on Network Pharmacology and Molecular Docking

open access: yesInternational Journal of Endocrinology, Volume 2025, Issue 1, 2025.
Objective Using network pharmacology and molecular docking technology to analyze the potential mechanism of the Jianpixiaoke recipe (JPXK recipe) in the treatment of type 2 diabetes mellitus (T2DM). Method This study searched and screened the active ingredients and corresponding T2DM‐related targets of different herbs in JPXK recipe from multiple ...
Huan Li   +5 more
wiley   +1 more source

Qi‐Gui‐Sheng‐Jiang‐San Decoction Regulating Hypoxia Response Through Non–Oxygen‐Dependent Pathway Improves Diabetic Kidney Disease: Coupling Network Pharmacology With Experimental Verification

open access: yesJournal of Diabetes Research, Volume 2025, Issue 1, 2025.
Background Diabetic kidney disease (DKD) is a major global cause of end‐stage renal disease. Emerging evidence suggests that hypoxia is a critical factor in the advancement of DKD. Traditional Chinese medicine (TCM) is an effective alternative therapy for DKD.
Yi-fan Liu   +11 more
wiley   +1 more source

Effects of Eyestalk Removal and Ecdysterone Infusion on Molting in Homarus americanus

open access: yes, 1972
Techniques of inducing precocious molting by introduction of the steroid ecdysterone were studied on the American lobster, Homarus americanus. The results indicate that ecdysterone, at the dosages used, while accelerating premolt processes, sufficiently
R. Warren Flint
core   +1 more source

Phytochemical Analysis and Anti‐inflammatory Potential of Floscopa Scandens Lour. and Exploring Ecdysterone as Promising Therapeutic Agent: An HR‐LCMS Screening and Molecular Docking Analysis

open access: yesChemistrySelect, Volume 9, Issue 40, October 25, 2024.
This study analyzed the bioactive compounds of Floscopa scandens Lour. using HR‐LCMS, isolating 21 phytoconstituents, including ecdysterone as the prominent. Molecular docking and molecular dynamic simulations revealed ecdysterone's anti‐inflammatory potential, confirming its therapeutic significance.
Sailaja Nambaaru   +5 more
wiley   +1 more source

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