Results 31 to 40 of about 1,564 (197)

Efficacy and Safety of Echinacoside in a Rat Osteopenia Model [PDF]

open access: yesEvidence-Based Complementary and Alternative Medicine, 2013
This study aimed to investigate the efficacy and safety of echinacoside (ECH) using an osteopenia rat model. Forty-eight 6-month-old female Sprague-Dawley rats were randomly divided into one sham-operated group (SHAM) and five OVX (ovariectomized) subgroups: SHAM with vehicle 0.5% carboxymethylcellulose sodium (0.5% CMC-Na) and OVX with vehicle (OVX ...
Yang, Xiaolin   +8 more
openaire   +2 more sources

The potential effects and mechanism of echinacoside powder in the treatment of Hirschsprung's Disease

open access: yesMathematical Biosciences and Engineering, 2023
<abstract><p>Possible complications, such as intestinal obstruction and inflammation of the intestinal tract, can have a detrimental effect on the prognosis after surgery for Hirschsprung disease. The aim of this study was to investigate the potential targets and mechanisms of action of echinacoside to improve the prognosis of Hirschsprung ...
Enyang He   +7 more
openaire   +3 more sources

Echinacoside Protects Against Dysfunction of Spermatogenesis Through the MAPK Signaling Pathway [PDF]

open access: yesReproductive Sciences, 2021
AbstractDysfunction at various levels of spermatogenesis (SD) is one of the important causes of infertility in men of reproductive age and requires advanced treatment strategies. Increasing evidence suggests that the therapeutic effects of echinacoside (ECH) mainly depend on their capacity to inhibit cell death.
Guifang Zhao   +4 more
openaire   +2 more sources

A comparative study of echinacoside, oleuropein content and antioxidant properties of different solvent extracts

open access: yesPakistan Journal of Pharmaceutical Sciences, 2022
Syringa pubescens Turcz is commonly used folk medicinal herb in west of Henan Province of China. In this work, water and various concentration of methanol, ethanol and acetone in water were used as solvent to extract echinacoside and oleuropein from S ...
from Syringa pubescens Turcz Yanfang Wu   +5 more
doaj   +1 more source

Concern about: Echinacoside exerts anti-tumor activity via the miR-503-3p/TGF-β1/Smad aixs in liver cancer

open access: yesCancer Cell International, 2021
We concentrated on a paper in Cancer Cell International “Echinacoside exerts anti-tumor activity via the miR-503-3p/TGF-β1/Smad aixs in liver cancer”. Echinacoside may be a safe and effective anti-tumor agent for the treatment of liver cancer.
Jiong Lin
doaj   +1 more source

Echinacoside Protects Dopaminergic Neurons Through Regulating IL-6/JAK2/STAT3 Pathway in Parkinson’s Disease Model

open access: yesFrontiers in Pharmacology, 2022
Echinacoside (ECH), the major active constituent of Cistanche deserticola, was found to exert neuroprotection through neurotrophic and anti-inflammatory functions in Parkinson’s disease (PD) models.
Xueping Yang   +12 more
doaj   +1 more source

Echinacoside-Zinc Nanomaterial Inhibits Skin Glycation by Suppressing the Transcriptional Activation of the Receptor for Advanced Glycation End-Products

open access: yes, 2023
Glycation is a nonenzymatically catalyzed spontaneous reaction that eventually leads to the formation of advanced glycation end-products (AGEs), which can bind to the receptor for AGEs (RAGE).
Huijuan Liu   +17 more
core   +1 more source

In vitro evaluation of the inhibition potential of echinacoside on human cytochrome P450 isozymes [PDF]

open access: yesBMC Complementary Medicine and Therapies, 2022
Abstract Background Echinacoside (ECH) possesses a wide range of biological activity. This present study analyzes the effect of ECH on cytochrome P450 isozymes (CYPs) activities of human liver microsomes. Methods The effect of ECH on CYPs enzyme activities were studied using
Yujie Wu   +3 more
openaire   +3 more sources

Echinacoside exerts its protective effects in a type 2 diabetes mellitus injury model via the AKT pathway

open access: yes, 2022
Echinacoside (ECH) is the main compound of Cistanche deserticola, which possesses antioxidant, antitumor, antifatigue, and anti-inflammatory properties.
Xiang-Ying Meng (8120918)   +7 more
core   +1 more source

Echinacoside attenuates lipopolysaccharide-induced acute lung injury in newborn mice via inactivation of NF- κB/NLRP3 signaling pathway [PDF]

open access: yes, 2020
Purpose: To investigate the effect of echinacoside (ECH) on acute lung injury (ALI) and the underlying mechanism of action.Methods: The ALI model was established through intranasal instillation of lipopolysaccharide (LPS).
Zheng, Yaling   +9 more
core   +1 more source

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