Results 21 to 30 of about 1,564 (197)

Neuroprotective Effects and Related Mechanisms of Echinacoside in MPTP-Induced PD Mice

open access: yesNeuropsychiatric Disease and Treatment, 2021
Zhen-Nian Zhang,1,* Zhen Hui,1,* Chang Chen,1 Yan Liang,1 Li-Li Tang,1 Su-Lei Wang,1 Cheng-Cheng Xu,1 Hui Yang,1 Jing-Si Zhang,2 Yang Zhao1 1Department of Neurology, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese ...
Zhang ZN   +9 more
doaj   +5 more sources

Echinacoside Increases Sperm Quantity in Rats by Targeting the Hypothalamic Androgen Receptor [PDF]

open access: yesScientific Reports, 2018
Male infertility is a major health issue with an estimated prevalence of 4.2% of male infertility worldwide. Our early work demonstrated that Cistanche extracts protect against sperm damage in mice and that echinacoside (ECH) is one of the major active ...
Bo Zhou   +4 more
core   +3 more sources

An In Silico Approach to Evaluate the Diabetic Wound Healing Potential of Phenylethanoid Glycoside in Inhibiting the Receptor for Advanced Glycation End Products (RAGE)

open access: yesMedical Sciences Forum, 2023
Diabetes mellitus (DM) is a chronic metabolic disorder and is associated with impaired wound healing. Non-healing leg and foot ulcers are a frequent significant consequence of diabetes and are caused by a combination of inadequate tissue perfusion ...
Ritika Baidya, Biswatrish Sarkar
doaj   +2 more sources

The role of echinacoside-based cross-linker nanoparticles in the treatment of osteoporosis [PDF]

open access: yesPeerJ
Background Current drugs for treating osteoporosis may lead to toxic side effects. Echinacoside (ECH) is a natural small molecule drug. This study examined and compared the therapeutic effects of cross-linker (CL)-ECH and ECH-free nanoparticles on ...
Dandan Hu   +3 more
core   +5 more sources

Echinacoside alleviates osteoarthritis in rats by activating the Nrf2-HO-1 signaling pathway

open access: yesImmunopharmacology and Immunotoxicology, 2022
Osteoarthritis (OA) is a progressive disease characterized by degeneration of cartilage and echinacoside (Ech) has anti-inflammatory and antioxidant effects in various human diseases.
Bin Zhang (64682), Zhijun Tan (429568)
core   +3 more sources

Beneficial Effects of Echinacoside on Diabetic Cardiomyopathy in Diabetic Db/Db Mice

open access: yesDrug Design, Development and Therapy, 2020
Xiang Zhang, Yarong Hao Department of Geriatrics, Renmin Hospital of Wuhan University, Hubei, People’s Republic of ChinaCorrespondence: Yarong HaoDepartment of Geriatrics, Renmin Hospital of Wuhan University, 99 Zhang Zhidong Road, Wuchang District,
Zhang X, Hao Y
doaj   +4 more sources

Effect of echinacoside on kidney fibrosis by inhibition of TGF-β1/Smads signaling pathway in the db/db mice model of diabetic nephropathy

open access: yesDrug Design, Development and Therapy, 2017
Fengjuan Tang,1 Yarong Hao,1 Xue Zhang,1 Jian Qin2 1Department of Geriatrics, 2Central Laboratory, Renmin Hospital of Wuhan University, Hubei, People’s Republic of China Abstract: Kidney fibrosis and renal tubular epithelial-to-mesenchymal ...
Tang FJ, Hao YR, Zhang X, Qin J
doaj   +1 more source

Key Lipoprotein Receptor Targeted Echinacoside-Liposomes Effective Against Parkinson’s Disease in Mice Model

open access: yesInternational Journal of Nanomedicine
Zemin Ou, Yun You, Hong Yi, Xiaoqian Liu, Yan Tong, Dewen Liu, Jinyu Wang Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, People’s Republic of ChinaCorrespondence: Dewen Liu; Jinyu Wang, Institute of Chinese ...
Ou Z   +6 more
doaj   +1 more source

Anxiofit-1 and reduction of subthreshold and mild anxiety: Evaluation of a health claim pursuant to article 14 of regulation (EC) No 1924/2006. [PDF]

open access: yesEFSA J
Abstract Following an application from Anxiofit Ltd. pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of Hungary, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked for an opinion on the scientific substantiation of a health claim related to Anxiofit‐1 and reduction of subthreshold and mild ...
EFSA Panel on Nutrition   +17 more
europepmc   +2 more sources

Echinacoside exhibits antidepressant-like effects through AMPAR–Akt/ERK–mTOR pathway stimulation and BDNF expression in mice

open access: yesChinese Medicine, 2022
Background Several natural products have been demonstrated to be effective in the treatment of depressive disorders. Echinacoside, a naturally occurring phenol extracted from Cistanche tubulosa, Echinacea angustifolia, and Cistanche spp, has a wide range
Han-Wen Chuang   +3 more
doaj   +1 more source

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