Results 71 to 80 of about 915 (185)
Evidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019 Background. The present study aimed to assess the effectiveness of clam extract in combination with atorvastatin against experimentally hyperlipidemia in rats. Method. Forty male rats were divided into 5 groups (8 rats /group): control, high fat diet (HFD), atorvastatin (AROR), clam extract (CE), and ATOR + CE. Results. The treatments with ATOR and /or
Ayman Saber Mohamed +5 more
wiley +1 more source
Immunology &Cell Biology, Volume 94, Issue 9, Page 861-874, October 2016., 2016 The purple sea urchin (Strongylocentrotus purpuratus) genome sequence contains a complex repertoire of genes encoding innate immune recognition proteins and homologs of important vertebrate immune regulatory factors. To characterize how this immune system is deployed within an experimentally tractable, intact animal, we investigate the immune ...
Eric CH Ho +8 more
wiley +1 more source
Natural Product Communications, 2020 In this study, valuable polyhydroxynaphthoquinone (PHNQ) pigments were recovered from sea urchin food waste and were investigated as a potential bioactive ingredient for cosmeceuticals.
Vo Mai Nhu Hieu +5 more
doaj +1 more source
The Immune Response of Acanthaster planci to Oxbile Injections and Antibiotic Treatment
Journal of Marine Sciences, Volume 2014, Issue 1, 2014., 2014 Bile salts have been recently identified as a rapid and effective method for killing A. planci. However the mechanistic basis of this new control method is poorly understood. This study explored the immune response(s) of A. planci and/or pathogenesis resulting from the injection of bile salts. To account for the possible role of pathogenesis in causing
Alexandra Grand +3 more
wiley +1 more source
Evidence-Based Complementary and Alternative Medicine, Volume 2011, Issue 1, 2011., 2011 One of the polyketide compounds, the naphthoquinone pigment echinochrome, is synthesized in sea urchin pigment cells. We analyzed polyketide synthase (pks) and sulfotransferase (sult) gene expression in embryos and larvae of the sea urchin Strongylocentrotus intermedius from various stages of development and in specific tissues of the adults.
Natalya V. Ageenko +2 more
wiley +1 more source
Atypical Protein Kinase Cs in Melanoma Progression [PDF]
, 2019 Melanoma is one of the fastest growing types of cancer worldwide in terms of incidence. To date, reports show over 92,000 new cases in the United States in 2018. Previously, we introduced protein kinase C-iota (PKC-ι) as an oncogene in melanoma.
Acevedo-Duncan, Mildred +2 more
core +2 more sources
Metabolomic Profiles on Antiblastic Cardiotoxicity: New Perspectives for Early Diagnosis and Cardioprotection [PDF]
, 2022 Antiblastic drugs-induced cardiomyopathy remains a relevant cause of morbidity and mortality, during and after chemotherapy, despite the progression in protective therapy against cardiovascular diseases and myocardial function.
Cadeddu Dessalvi, Christian +6 more
core +2 more sources
Marine Polyhydroxynaphthoquinone, Echinochrome A: Prevention of Atherosclerotic Inflammation and Probable Molecular Targets [PDF]
Journal of Clinical Medicine, 2020 The effect of low doses of echinochrome A (EchA), a natural polyhydroxy-1,4-naphthoquinone pigment from the sea urchin Scaphechinus mirabilis, has been studied in clinical trials, when it was used as an active substance of the drug Histochrome® and biologically active supplement Thymarin.
Aleksandr A. Artyukov +6 more
openaire +2 more sources
Synthesis of Polyhydroxylated Aminonaphthazarins Related to Natural Pigments
Natural Product Communications, 2018 Amino analogs of echinochrome and ethylmompain, metabolites of sea urchins Scaphechinus mirabilis and Echinothrix diadema , and amino analogs of cristazarin, a metabolite of lichen Cladonia cristatella , were synthesized.
Galina I. Melman +4 more
doaj +1 more source
SUPRESSION OF MICROSOMAL OXIDATION WEAKENS HISTOCHROME’S DIURETIC EFFECT AT RATS
Бюллетень сибирской медицины, 2013 Histochrome is the medicinal form of echinochrome (2, 3, 5, 6, 8-pentahydroxy-7-ethyl-1,4-naphthoquinone). Arisen during clinical application of the drug questions concerning its biotransformation have predetermined the aim of this research: to study ...
O. S. Talalaeva +5 more
doaj +1 more source