Antiviral and Antioxidant Properties of Echinochrome A [PDF]
Marine Drugs, 2018 The aim of this study was to examine the in vitro antioxidant and antiviral activities of echinochrome A and echinochrome-based antioxidant composition against tick-borne encephalitis virus (TBEV) and herpes simplex virus type 1 (HSV-1).
Galina Leonova +2 more
exaly +5 more sources
Multifaceted Clinical Effects of Echinochrome [PDF]
Marine Drugs, 2021 The marine drug histochrome is a special natural antioxidant. The active substance of the drug is echinochrome A (Ech A, 7-ethyl-2,3,5,6,8-pentahydroxy-1,4-naphthoquinone), the most abundant quinonoid pigment in sea urchins.
Elena Vasileva +2 more
exaly +7 more sources
Implication of Echinochrome A in the Plasticity and Damage of Intestinal Epithelium [PDF]
Marine Drugs, 2022 The diverse therapeutic feasibility of the sea urchin-derived naphthoquinone pigment, Echinochrome A (Ech A), has been studied. Simple and noninvasive administration routes should be explored, to obtain the feasibility. Although the therapeutic potential
Ji-Su Ahn +16 more
doaj +4 more sources
Echinochrome A Treatment Alleviates Fibrosis and Inflammation in Bleomycin-Induced Scleroderma [PDF]
Marine Drugs, 2021 Scleroderma is an autoimmune disease caused by the abnormal regulation of extracellular matrix synthesis and is activated by non-regulated inflammatory cells and cytokines.
Ki-Tae Ha +2 more
exaly +5 more sources
Echinochrome A Inhibits Melanogenesis in B16F10 Cells by Downregulating CREB Signaling [PDF]
Marine Drugs, 2022 Excessive increase in melanin pigment in the skin can be caused by a variety of environmental factors, including UV radiation, and can result in spots, freckles, and skin cancer.
Mi Ran Choi +11 more
doaj +4 more sources
Effect of Echinochrome A on Submandibular Gland Dysfunction in Ovariectomized Rats [PDF]
Marine Drugs, 2022 Post-menopausal dry mouth or xerostomia is caused by reduced salivary secretion. This study aimed to investigate the efficacy of echinochrome A (Ech A) in alleviating submandibular gland dysfunctions in ovariectomized rats that mimic menopause.
Ji-Min Kim +12 more
doaj +4 more sources
Hematopoietic effect of echinochrome on phenylhydrazine-induced hemolytic anemia in rats [PDF]
PeerJ, 2023 Background Hemolytic anemia (HA) is a serious health condition resulting from reduced erythrocytes’ average life span. Echinochrome (Ech) is a dark-red pigment found in shells and spines of sea urchins.
Mona S. E. F. El-Shehry +11 more
doaj +5 more sources
Echinochrome A Treatment Alleviates Atopic Dermatitis-like Skin Lesions in NC/Nga Mice via IL-4 and IL-13 Suppression [PDF]
Marine Drugs, 2021 Atopic dermatitis (AD) is a chronic inflammatory skin disease in which skin barrier dysfunction leads to dryness, pruritus, and erythematous lesions. AD is triggered by immune imbalance and oxidative stress.
Elena Vasileva +2 more
exaly +4 more sources
Liposomal Form of the Echinochrome-Carrageenan Complex [PDF]
Marine Drugs, 2018 Inclusion of drugs in liposomes offers the potential for localized and sustained delivery to mucosal surfaces. The inclusion of the carrageenan matrix with echinochrome A ((Ech)—the active substance of the drug Histochrome) in liposomes was studied.
Irina M. Yermak +6 more
doaj +3 more sources
Echinochrome A Reverses Kidney Abnormality and Reduces Blood Pressure in a Rat Model of Preeclampsia [PDF]
Marine Drugs, 2022 We aimed to observe the effects of Echinochrome A (Ech A) on systemic changes using a rat model of preeclampsia. The results showed that an infusion of angiotensin II (Ang II) through an osmotic pump (1 μg/kg/min) on GD 8 increased systolic and diastolic
Huixing Cui +6 more
doaj +2 more sources