Seas of Renewal: Turning Sea Urchin Waste into Polyhydroxynaphtoquinone-Collagen Biomaterials for Regenerative Medicine. [PDF]
Mar Biotechnol (NY): Chronic wounds and skin ulcers pose significant challenges to healthcare systems globally, necessitating innovative approaches to accelerate healing processes.
Martinelli G +14 more
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Marine Drugs, 2017 The possibility of using different types of carrageenans (CRG) as matrixes for incorporating of echinochrome A (Ech) was investigated. Ech interacts with carrageenans and is incorporated into the macromolecular structure of the polysaccharide.
Irina M. Yermak +7 more
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Antiherpetic Activity of Carrageenan Complex with Echinochrome A and Its Liposomal Form. [PDF]
Int J Mol Sci, 2022 Herpes simplex virus (HSV) infections, the incidence of which is still widespread throughout the world, are actualizing the search and development of new, more effective antiherpetic drugs. The development of multifunctional drug delivery systems, including liposome-based ones, has become a relevant and attractive concept in nanotechnology. The ability
Krylova NV +7 more
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Ecotoxicology and Environmental SafetyEchinochrome A (EchA), a marine-derived natural product, has shown promise in treating cardiovascular and inflammatory diseases due to its antioxidant and anti-inflammatory properties. However, its cardiac safety remains underexplored.
Su-Jin Lee +11 more
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Echinochrome Ameliorates Physiological, Immunological, and Histopathological Alterations Induced by Ovalbumin in Asthmatic Mice by Modulating the Keap1/Nrf2 Signaling Pathway. [PDF]
Mar Drugs, 2023 Abdelmawgood IA +7 more
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Echinochrome A inhibits HMGB1-induced vascular smooth muscle cell migration by suppressing osteopontin expression. [PDF]
Korean J Physiol PharmacolEchinochrome A (Ech A) isolated from marine organisms is a therapeutic effector for various cardiovascular diseases, but its precise mechanisms are unclear. This study identified the role and mechanisms mediating the effects of Ech A on the migration of vascular smooth muscle cells (VSMCs) induced by high-mobility group box 1 (HMGB1).
Kim JY, Bae HE, Bae SS, Sung H, Kim CD.
europepmc +3 more sources
Interaction between nanomaterials and the innate immune system across evolution
Biological Reviews, Volume 98, Issue 3, Page 747-774, June 2023., 2023 ABSTRACT Interaction of engineered nanomaterials (ENMs) with the immune system mainly occurs with cells and molecules of innate immunity, which are present in interface tissues of living organisms. Immuno‐nanotoxicological studies aim at understanding if and when such interaction is inconsequential or may cause irreparable damage. Since innate immunity
Diana Boraschi +5 more
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UJI AKTIVITAS ANTIHIPERGLIKEMIA EKSTRAK ETANOL 70% Echinometra mathaei PADA TIKUS PUTIH JANTAN GALUR WISTAR YANG DIINDUKSI ALOKSAN [PDF]
, 2021 : Sea urchin (Echinometra mathaei) contains a compound of Echinochrome A, which is a polyhydroxy naphthoquinone that is known to be potential antioxidant.
angelica, Nana +2 more
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Marine Polyhydroxynaphthoquinone, Echinochrome A: Prevention of Atherosclerotic Inflammation and Probable Molecular Targets [PDF]
Journal of Clinical Medicine, 2020 The effect of low doses of echinochrome A (EchA), a natural polyhydroxy-1,4-naphthoquinone pigment from the sea urchin Scaphechinus mirabilis, has been studied in clinical trials, when it was used as an active substance of the drug Histochrome® and biologically active supplement Thymarin.
Aleksandr A. Artyukov +6 more
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The sea urchin arbacia lixula: A novel natural source of astaxanthin [PDF]
, 2021 none8noSeveral echinoderms, including sea urchins, are valuable sources of bioactive compounds but their nutraceutical potential is largely unexplored.
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