Results 31 to 40 of about 114,625,497 (147)
Echinochrome A Reduces Colitis in Mice and Induces In Vitro Generation of Regulatory Immune Cells
Marine Drugs, 2019 Echinochrome A (Ech A), a natural pigment extracted from sea urchins, is the active ingredient of a marine-derived pharmaceutical called ‘histochrome’.
Su-Jeong Oh +10 more
doaj +2 more sources
Effectiveness of Echinochrome on HFD-Induced Hyperlipidemia in Rats [PDF]
Natural Products and Bioprospecting, 2019 Obesity has been identified with an expanded danger of a progression of illnesses that include different organ-frameworks of the body. In the present examination, we evaluated the hypolipidemic properties of Echinochrome (Ech) pigment in a high-fat diet (
Sohair R. Fahmy +4 more
doaj +3 more sources
ADJUVANT EFFECT OF TUBULAR IMMUNOSTIMULATING COMPLEXES MODIFIED BY ECHINOCHROME A, TOWARDS A PORE PROTEIN FROM YERSINIA PSEUDOTUBERCULOSIS [PDF]
Медицинская иммунология, 2014 . We investigated immunogenic properties of vaccine constructs based on lipid-saponin tubular immunostimulating complexes (TI-complexes), and an individual antigen, i.e., monomeric and trimeric forms of porin isolated from Yersinia ...
A. V. Tsybulsky +6 more
doaj +2 more sources
Marine Drugs, 2018 Echinochrome A (EchA) is a marine bioproduct extracted from sea urchins having antioxidant, antimicrobial, anti-inflammatory, and chelating effects, and is the active component of the clinical drug histochrome.
Hyoung Kyu Kim +11 more
doaj +2 more sources
The Anti-Inflammatory Effect of Carrageenan/Echinochrom Complex at Experimental Endotoxemia. [PDF]
Int J Mol Sci, 2022 The anti-inflammatory effects of the CRG/Ech complex in LPS-induced endotoxemia were investigated in vivo in mice and in vitro in LPS-stimulated RAW 264.7 cells and peritoneal macrophages. The results indicated that the CRG/Ech complex suppressed the LPS-induced inflammatory response by reducing the production of ROS and NO in the macrophages ...
Yermak IM +7 more
europepmc +3 more sources
Marine Drugs, 2021 Echinochrome A (Ech A, 7-ethyl-2,3,5,6,8-pentahydroxy-1,4-naphthoquinone) has been known to exhibit anti-oxidative and anti-inflammatory effects. However, no study has been carried out on the efficacy of Ech A against skin photoaging; this process is ...
Jung Eun Seol +10 more
doaj +2 more sources
Ecotoxicology and Environmental SafetyEchinochrome A (EchA), a marine-derived natural product, has shown promise in treating cardiovascular and inflammatory diseases due to its antioxidant and anti-inflammatory properties. However, its cardiac safety remains underexplored.
Su-Jin Lee +11 more
doaj +2 more sources
Multi-omic analysis reveals genes and proteins integral to bioactivity of Echinochrome A isolated from the waste stream of the sea urchin industry in Aotearoa New Zealand. [PDF]
Food Sci NutrThe mechanism of action of Echinochrome A (Ech A) was evaluated using unbiased genomic and proteomic analyses. Growth analyses of gene deletions and measurements of protein abundance identified the importance of 20 genes and 92 proteins. The antioxidant activity of Ech A may begin with alterations in DNA replication, followed by iron chelation and ...
Hammond J +7 more
europepmc +2 more sources
AquaTechnica, 2021 Within the framework of the generation of research studies in applied biology for the diversification of aquaculture in Ecuador, the native sea urchin Arbacia stellata was considered with potential for its aquaculture and extraction of macroenergetic ...
Javier José Palma-Chávez +2 more
doaj +1 more source
Echinochrome Prevents Sulfide Catabolism-Associated Chronic Heart Failure after Myocardial Infarction in Mice. [PDF]
Mar Drugs, 2023 Abnormal sulfide catabolism, especially the accumulation of hydrogen sulfide (H2S) during hypoxic or inflammatory stresses, is a major cause of redox imbalance-associated cardiac dysfunction.
Tang X +15 more
europepmc +2 more sources