Development of Novel Pharmaceutical Forms of the Marine Bioactive Pigment Echinochrome A Enabling Alternative Routes of Administration [PDF]
Marine Drugs, 2023 Echinochrome A (EchA), a marine bioactive pigment isolated from various sea urchin species, is the active agent of the clinically approved drug Histochrome®.
Stefanos Kikionis +8 more
doaj +5 more sources
ANTIVIRAL AND ANTIOXIDANT ACTIVITY OF THE COMPOSITION OF COMPOUNDS BASED ON ECHINOCHROME A [PDF]
Журнал микробиологии, эпидемиологии и иммунобиологии, 2019 The aim of this study was to examine in vitro the antioxidant and antiviral activity of echinochrome A and echinochrome-based antioxidant composition against tick-borne encephalitis virus (TBEV) and herpes simplex virus type 1 (HSV-1).
N. V. Krylova +8 more
doaj +4 more sources
Isolation and Structure Determination of Echinochrome A Oxidative Degradation Products [PDF]
Molecules, 2020 Echinochrome A (Ech A, 1) is one of the main pigments of several sea urchin species and is registered in the Russian pharmacopeia as an active drug substance (Histochrome®), used in the fields of cardiology and ophthalmology.
Natalia P. Mishchenko +5 more
doaj +4 more sources
Echinochrome A Protects Mitochondrial Function in Cardiomyocytes against Cardiotoxic Drugs [PDF]
Marine Drugs, 2014 Echinochrome A (Ech A) is a naphthoquinoid pigment from sea urchins that possesses antioxidant, antimicrobial, anti-inflammatory and chelating abilities.
Seung Hun Jeong +10 more
doaj +5 more sources
Regulation of Inflammation-Mediated Endothelial to Mesenchymal Transition with Echinochrome a for Improving Myocardial Dysfunction [PDF]
Marine Drugs, 2022 Endothelial–mesenchymal transition (EndMT) is a process by which endothelial cells (ECs) transition into mesenchymal cells (e.g., myofibroblasts and smooth muscle cells) and induce fibrosis of cells/tissues, due to ischemic conditions in the heart ...
Byeong-Wook Song +14 more
doaj +3 more sources
Antiherpetic Activity of Carrageenan Complex with Echinochrome A and Its Liposomal Form. [PDF]
Int J Mol Sci, 2022 Herpes simplex virus (HSV) infections, the incidence of which is still widespread throughout the world, are actualizing the search and development of new, more effective antiherpetic drugs. The development of multifunctional drug delivery systems, including liposome-based ones, has become a relevant and attractive concept in nanotechnology. The ability
Krylova NV +7 more
europepmc +4 more sources
Multiple Effects of Echinochrome A on Selected Ion Channels Implicated in Skin Physiology [PDF]
Marine Drugs, 2023 Echinochrome A (Ech A), a naphthoquinoid pigment from sea urchins, is known to have anti-inflammatory and analgesic effects that have been suggested to be mediated by antioxidant activity and intracellular signaling modulation.
Sung Eun Kim +8 more
doaj +3 more sources
Echinochrome A Prevents Diabetic Nephropathy by Inhibiting the PKC-Iota Pathway and Enhancing Renal Mitochondrial Function in db/db Mice [PDF]
Marine Drugs, 2023 Echinochrome A (EchA) is a natural bioproduct extracted from sea urchins, and is an active component of the clinical drug, Histochrome®. EchA has antioxidant, anti-inflammatory, and antimicrobial effects. However, its effects on diabetic nephropathy (DN)
Trong Kha Pham +11 more
doaj +3 more sources
Acetylcholinesterase Inhibitory Activity of Pigment Echinochrome A from Sea Urchin Scaphechinus mirabilis [PDF]
Marine Drugs, 2014 Echinochrome A (EchA) is a dark-red pigment of the polyhydroxynaphthoquinone class isolated from sea urchin Scaphechinus mirabilis. Acetylcholinesterase (AChE) inhibitors are used in the treatment of various neuromuscular disorders, and are considered as
Sung Ryul Lee +9 more
doaj +5 more sources
Marine Drugs, 2014 Echinochrome A (Ech A) is a natural pigment from sea urchins that has been reported to have antioxidant properties and a cardio protective effect against ischemia reperfusion injury.
Nari Kim +2 more
exaly +4 more sources