Results 11 to 20 of about 408 (132)
Multifaceted Clinical Effects of Echinochrome [PDF]
Marine Drugs, 2021 The marine drug histochrome is a special natural antioxidant. The active substance of the drug is echinochrome A (Ech A, 7-ethyl-2,3,5,6,8-pentahydroxy-1,4-naphthoquinone), the most abundant quinonoid pigment in sea urchins.
Elena Vasileva +2 more
exaly +7 more sources
Implication of Echinochrome A in the Plasticity and Damage of Intestinal Epithelium [PDF]
Marine Drugs, 2022 The diverse therapeutic feasibility of the sea urchin-derived naphthoquinone pigment, Echinochrome A (Ech A), has been studied. Simple and noninvasive administration routes should be explored, to obtain the feasibility. Although the therapeutic potential
Ji-Su Ahn +16 more
doaj +4 more sources
Liposomal Form of the Echinochrome-Carrageenan Complex [PDF]
Marine Drugs, 2018 Inclusion of drugs in liposomes offers the potential for localized and sustained delivery to mucosal surfaces. The inclusion of the carrageenan matrix with echinochrome A ((Ech)—the active substance of the drug Histochrome) in liposomes was studied.
Natalia Mishchenko +2 more
exaly +5 more sources
Effect of Echinochrome A on Submandibular Gland Dysfunction in Ovariectomized Rats [PDF]
Marine Drugs, 2022 Post-menopausal dry mouth or xerostomia is caused by reduced salivary secretion. This study aimed to investigate the efficacy of echinochrome A (Ech A) in alleviating submandibular gland dysfunctions in ovariectomized rats that mimic menopause.
Ji-Min Kim +12 more
doaj +4 more sources
Isolation and Structure Determination of Echinochrome A Oxidative Degradation Products [PDF]
Molecules, 2020 Echinochrome A (Ech A, 1) is one of the main pigments of several sea urchin species and is registered in the Russian pharmacopeia as an active drug substance (Histochrome®), used in the fields of cardiology and ophthalmology.
Elena Vasileva +2 more
exaly +5 more sources
Antiherpetic Activity of Carrageenan Complex with Echinochrome A and Its Liposomal Form [PDF]
International Journal of Molecular Sciences, 2022 Herpes simplex virus (HSV) infections, the incidence of which is still widespread throughout the world, are actualizing the search and development of new, more effective antiherpetic drugs. The development of multifunctional drug delivery systems, including liposome-based ones, has become a relevant and attractive concept in nanotechnology. The ability
Olga Iunikhina +2 more
exaly +4 more sources
Multiple Effects of Echinochrome A on Selected Ion Channels Implicated in Skin Physiology [PDF]
Marine Drugs, 2023 Echinochrome A (Ech A), a naphthoquinoid pigment from sea urchins, is known to have anti-inflammatory and analgesic effects that have been suggested to be mediated by antioxidant activity and intracellular signaling modulation.
Sung Eun Kim +8 more
doaj +2 more sources
PHNQ from Evechinus chloroticus Sea Urchin Supplemented with Calcium Promotes Mineralization in Saos-2 Human Bone Cell Line [PDF]
Marine Drugs, 2020 Polyhydroxylated naphthoquinones (PHNQs), known as spinochromes that can be extracted from sea urchins, are bioactive compounds reported to have medicinal properties and antioxidant activity.
Yakun Hou +9 more
doaj +2 more sources
Marine Drugs, 2020 Here, we investigated the effects of sex hormones on extracellular matrix (ECM)-related gene expression in the vocal fold lamina propria of ovariectomized (after ovary removal) rats and verified whether echinochrome A (ECH) exerts any therapeutic effects
Keunyoung Kim +2 more
exaly +3 more sources
Marine Drugs, 2014 Echinochrome A (Ech A) is a natural pigment from sea urchins that has been reported to have antioxidant properties and a cardio protective effect against ischemia reperfusion injury.
Nari Kim +2 more
exaly +3 more sources