Antiviral and Antioxidant Properties of Echinochrome A [PDF]
Marine Drugs, 2018 The aim of this study was to examine the in vitro antioxidant and antiviral activities of echinochrome A and echinochrome-based antioxidant composition against tick-borne encephalitis virus (TBEV) and herpes simplex virus type 1 (HSV-1).
Sergey A. Fedoreyev +9 more
doaj +5 more sources
Echinochrome A Treatment Alleviates Fibrosis and Inflammation in Bleomycin-Induced Scleroderma [PDF]
Marine Drugs, 2021 Scleroderma is an autoimmune disease caused by the abnormal regulation of extracellular matrix synthesis and is activated by non-regulated inflammatory cells and cytokines.
Gyu-Tae Park +13 more
doaj +5 more sources
Effect of Echinochrome A on Submandibular Gland Dysfunction in Ovariectomized Rats [PDF]
Marine Drugs, 2022 Post-menopausal dry mouth or xerostomia is caused by reduced salivary secretion. This study aimed to investigate the efficacy of echinochrome A (Ech A) in alleviating submandibular gland dysfunctions in ovariectomized rats that mimic menopause.
Ji-Min Kim +12 more
doaj +4 more sources
Implication of Echinochrome A in the Plasticity and Damage of Intestinal Epithelium [PDF]
Marine Drugs, 2022 The diverse therapeutic feasibility of the sea urchin-derived naphthoquinone pigment, Echinochrome A (Ech A), has been studied. Simple and noninvasive administration routes should be explored, to obtain the feasibility. Although the therapeutic potential
Ji-Su Ahn +16 more
doaj +4 more sources
Echinochrome A Increases Mitochondrial Mass and Function by Modulating Mitochondrial Biogenesis Regulatory Genes [PDF]
Marine Drugs, 2014 Echinochrome A (Ech A) is a natural pigment from sea urchins that has been reported to have antioxidant properties and a cardio protective effect against ischemia reperfusion injury.
Seung Hun Jeong +11 more
doaj +6 more sources
Regulation of Inflammation-Mediated Endothelial to Mesenchymal Transition with Echinochrome a for Improving Myocardial Dysfunction [PDF]
Marine Drugs, 2022 Endothelial–mesenchymal transition (EndMT) is a process by which endothelial cells (ECs) transition into mesenchymal cells (e.g., myofibroblasts and smooth muscle cells) and induce fibrosis of cells/tissues, due to ischemic conditions in the heart ...
Byeong-Wook Song +14 more
doaj +4 more sources
Echinochrome A Treatment Alleviates Atopic Dermatitis-like Skin Lesions in NC/Nga Mice via IL-4 and IL-13 Suppression [PDF]
Marine Drugs, 2021 Atopic dermatitis (AD) is a chronic inflammatory skin disease in which skin barrier dysfunction leads to dryness, pruritus, and erythematous lesions. AD is triggered by immune imbalance and oxidative stress.
Hyeong Rok Yun +11 more
doaj +4 more sources
Echinochrome A Improves Exercise Capacity during Short-Term Endurance Training in Rats [PDF]
Marine Drugs, 2015 Echinochrome A (Echi A) improves mitochondrial function in the heart; however, its effects on skeletal muscle are still unclear. We hypothesized that Echi A administration during short-term exercise may improve exercise capacity. Twenty-four male Sprague-
Dae Yun Seo +7 more
doaj +6 more sources
Sea Urchin Pigments: Echinochrome A and Its Potential Implication in the Cytokine Storm Syndrome [PDF]
Marine Drugs, 2021 Background: Echinochrome A (EchA) is a pigment from sea urchins. EchA is a polyhydroxylated 1,4-naphthoquinone that contains several hydroxyl groups appropriate for free-radical scavenging and preventing redox imbalance. EchA is the most studied molecule
Tamara Rubilar +3 more
doaj +5 more sources
Echinochrome A Protects against Ultraviolet B-induced Photoaging by Lowering Collagen Degradation and Inflammatory Cell Infiltration in Hairless Mice [PDF]
Marine Drugs, 2021 Echinochrome A (Ech A, 7-ethyl-2,3,5,6,8-pentahydroxy-1,4-naphthoquinone) has been known to exhibit anti-oxidative and anti-inflammatory effects. However, no study has been carried out on the efficacy of Ech A against skin photoaging; this process is ...
Jung Eun Seol +10 more
doaj +4 more sources