Marine Drugs, 2019 Of late, researchers have taken interest in alternative medicines for the treatment of brain ischemic stroke, where full recovery is rarely seen despite advanced medical technologies.
Ran Kim +2 more
exaly +4 more sources
Echinochrome A Improves Exercise Capacity during Short-Term Endurance Training in Rats
Marine Drugs, 2015 Echinochrome A (Echi A) improves mitochondrial function in the heart; however, its effects on skeletal muscle are still unclear. We hypothesized that Echi A administration during short-term exercise may improve exercise capacity. Twenty-four male Sprague-
Natalya Mishchenko +2 more
exaly +4 more sources
PHNQ from Evechinus chloroticus Sea Urchin Supplemented with Calcium Promotes Mineralization in Saos-2 Human Bone Cell Line [PDF]
Marine Drugs, 2020 Polyhydroxylated naphthoquinones (PHNQs), known as spinochromes that can be extracted from sea urchins, are bioactive compounds reported to have medicinal properties and antioxidant activity.
Yakun Hou +9 more
doaj +3 more sources
Sea Urchin Pigments: Echinochrome A and Its Potential Implication in the Cytokine Storm Syndrome [PDF]
Marine Drugs, 2021 Background: Echinochrome A (EchA) is a pigment from sea urchins. EchA is a polyhydroxylated 1,4-naphthoquinone that contains several hydroxyl groups appropriate for free-radical scavenging and preventing redox imbalance. EchA is the most studied molecule
Tamara Rubilar +3 more
doaj +3 more sources
Marine Drugs, 2017 The possibility of using different types of carrageenans (CRG) as matrixes for incorporating of echinochrome A (Ech) was investigated. Ech interacts with carrageenans and is incorporated into the macromolecular structure of the polysaccharide.
Natalya Mishchenko +2 more
exaly +4 more sources
Echinochrome pigment attenuates diabetic nephropathy in the models of type 1 and type 2 diabetes [PDF]
Сахарный диабет, 2016 Background. The main complication of diabetes mellitus is diabetic nephropathy in both types, which is a main reason for renal failure. Echinochrome substance present in sea urchin shells and spines and possesses high antioxidant activity.Aim.
Amel Mahmoud Soliman +2 more
doaj +2 more sources
Activity of compounds containing echinochrome A against herpes simplex virus type 2 in vitro and in vivo [PDF]
Журнал микробиологии, эпидемиологии и иммунобиологии, 2019 The aim of the work was to study the activity of echinochrome A, a naphthoquinoid pigment from sea urchins, and its antioxidant composition against herpes simplex virus type 2 (HSV-2) in vitro and in vivo.Materials and methods.
N. V. Krylova +9 more
doaj +2 more sources
COMPARATIVE STUDY OF ECHINOCHROME A, OXYGENATED CAROTENOIDS, GINSENOSIDE Rh2, LUTEOLIN DISULFATE AND METFORMIN AS A MEAN TO POTENTIATE ANTITUMOR EFFECT OF DOXORUBICIN [PDF]
Медицинская иммунология, 2018 This work concerned a comparative study of potentiating effects produced by some drugs of natural origin, as well as metformin, upon antitumor activity of doxorubicin. An increased therapeutic efficacy of doxorubicin used in combination with echinochrome
A. V. Tsybulsky +5 more
doaj +2 more sources
Effects of Carrageenans on Biological Properties of Echinochrome [PDF]
Marine Drugs, 2018 Sea urchin pigment echinochrome A (Ech), a water-insoluble compound, is the active substance in the cardioprotective and antioxidant drug Histochrome® (PIBOC FEB RAS, Moscow, Russia). It has been established that Ech dissolves in aqueous solutions of carrageenans (CRGs).
Ekaterina V. Sokolova +6 more
openaire +4 more sources
Marine Drugs, 2020 Here, we investigated the effects of sex hormones on extracellular matrix (ECM)-related gene expression in the vocal fold lamina propria of ovariectomized (after ovary removal) rats and verified whether echinochrome A (ECH) exerts any therapeutic effects
Ji Min Kim +12 more
doaj +2 more sources