Multifaceted Clinical Effects of Echinochrome [PDF]
Marine Drugs, 2021 The marine drug histochrome is a special natural antioxidant. The active substance of the drug is echinochrome A (Ech A, 7-ethyl-2,3,5,6,8-pentahydroxy-1,4-naphthoquinone), the most abundant quinonoid pigment in sea urchins.
Elena Vasileva +2 more
exaly +8 more sources
Antiviral and Antioxidant Properties of Echinochrome A [PDF]
Marine Drugs, 2018 The aim of this study was to examine the in vitro antioxidant and antiviral activities of echinochrome A and echinochrome-based antioxidant composition against tick-borne encephalitis virus (TBEV) and herpes simplex virus type 1 (HSV-1).
Galina Leonova +2 more
exaly +6 more sources
Hematopoietic effect of echinochrome on phenylhydrazine-induced hemolytic anemia in rats. [PDF]
PeerJ, 2023 Background Hemolytic anemia (HA) is a serious health condition resulting from reduced erythrocytes’ average life span. Echinochrome (Ech) is a dark-red pigment found in shells and spines of sea urchins.
El-Shehry MSEF +11 more
europepmc +6 more sources
Implication of Echinochrome A in the Plasticity and Damage of Intestinal Epithelium. [PDF]
Mar Drugs, 2022 The diverse therapeutic feasibility of the sea urchin-derived naphthoquinone pigment, Echinochrome A (Ech A), has been studied. Simple and noninvasive administration routes should be explored, to obtain the feasibility. Although the therapeutic potential
Ahn JS +16 more
europepmc +5 more sources
Effect of Echinochrome A on Submandibular Gland Dysfunction in Ovariectomized Rats. [PDF]
Mar Drugs, 2022 Post-menopausal dry mouth or xerostomia is caused by reduced salivary secretion. This study aimed to investigate the efficacy of echinochrome A (Ech A) in alleviating submandibular gland dysfunctions in ovariectomized rats that mimic menopause.
Kim JM +12 more
europepmc +5 more sources
Echinochrome Prevents Sulfide Catabolism-Associated Chronic Heart Failure after Myocardial Infarction in Mice. [PDF]
Mar Drugs, 2023 Abnormal sulfide catabolism, especially the accumulation of hydrogen sulfide (H2S) during hypoxic or inflammatory stresses, is a major cause of redox imbalance-associated cardiac dysfunction.
Tang X +15 more
europepmc +3 more sources
Interaction of Liposomes Containing the Carrageenan/Echinochrome Complex with Human HaCaT Keratinocytes In Vitro. [PDF]
Mar DrugsLiposomal drug delivery systems are successfully used in various fields of medicine for external and systemic applications. Marine organisms contain biologically active substances that have a unique structure and exhibit a wide range of biological ...
Menchinskaya ES +7 more
europepmc +3 more sources
Echinochrome A Reverses Kidney Abnormality and Reduces Blood Pressure in a Rat Model of Preeclampsia. [PDF]
Mar Drugs, 2022 We aimed to observe the effects of Echinochrome A (Ech A) on systemic changes using a rat model of preeclampsia. The results showed that an infusion of angiotensin II (Ang II) through an osmotic pump (1 μg/kg/min) on GD 8 increased systolic and diastolic
Cui H +6 more
europepmc +3 more sources
Echinochrome Ameliorates Physiological, Immunological, and Histopathological Alterations Induced by Ovalbumin in Asthmatic Mice by Modulating the Keap1/Nrf2 Signaling Pathway. [PDF]
Mar Drugs, 2023 Asthma is a persistent inflammatory disease of the bronchi characterized by oxidative stress, airway remodeling, and inflammation. Echinochrome (Ech) is a dark-red pigment with antioxidant and anti-inflammatory activities.
Abdelmawgood IA +7 more
europepmc +2 more sources
Multi-target bioactivity of summer quinones production in the Persian Gulf burrowing black-type sea urchin. [PDF]
Heliyon, 2022 After harvesting the sea urchin gonads for Japanese food “uni” echinoculture systems, the remaining shells and spines are considered waste. However, the material of shells and spines is thought to be rich in natural bioactive molecules. The current study
Soleimani S +3 more
europepmc +2 more sources