Hematopoietic effect of echinochrome on phenylhydrazine-induced hemolytic anemia in rats [PDF]
PeerJ, 2023 Background Hemolytic anemia (HA) is a serious health condition resulting from reduced erythrocytes’ average life span. Echinochrome (Ech) is a dark-red pigment found in shells and spines of sea urchins.
Mona S. E. F. El-Shehry +11 more
doaj +6 more sources
Echinochrome A Treatment Alleviates Fibrosis and Inflammation in Bleomycin-Induced Scleroderma [PDF]
Marine Drugs, 2021 Scleroderma is an autoimmune disease caused by the abnormal regulation of extracellular matrix synthesis and is activated by non-regulated inflammatory cells and cytokines.
Gyu-Tae Park +2 more
exaly +7 more sources
Echinochrome A Inhibits Melanogenesis in B16F10 Cells by Downregulating CREB Signaling [PDF]
Marine Drugs, 2022 Excessive increase in melanin pigment in the skin can be caused by a variety of environmental factors, including UV radiation, and can result in spots, freckles, and skin cancer.
Mi Ran Choi +11 more
doaj +6 more sources
Echinochrome A Increases Mitochondrial Mass and Function by Modulating Mitochondrial Biogenesis Regulatory Genes [PDF]
Marine Drugs, 2014 Echinochrome A (Ech A) is a natural pigment from sea urchins that has been reported to have antioxidant properties and a cardio protective effect against ischemia reperfusion injury.
Jubert Marquez +2 more
exaly +8 more sources
Interaction of Liposomes Containing the Carrageenan/Echinochrome Complex with Human HaCaT Keratinocytes In Vitro [PDF]
Marine DrugsLiposomal drug delivery systems are successfully used in various fields of medicine for external and systemic applications. Marine organisms contain biologically active substances that have a unique structure and exhibit a wide range of biological ...
Ekaterina S. Menchinskaya +7 more
doaj +4 more sources
Echinochrome Ameliorates Physiological, Immunological, and Histopathological Alterations Induced by Ovalbumin in Asthmatic Mice by Modulating the Keap1/Nrf2 Signaling Pathway [PDF]
Marine Drugs, 2023 Asthma is a persistent inflammatory disease of the bronchi characterized by oxidative stress, airway remodeling, and inflammation. Echinochrome (Ech) is a dark-red pigment with antioxidant and anti-inflammatory activities.
Islam Ahmed, Noha Mahana, Hader I Sakr
exaly +4 more sources
Echinochrome A Reverses Kidney Abnormality and Reduces Blood Pressure in a Rat Model of Preeclampsia [PDF]
Marine Drugs, 2022 We aimed to observe the effects of Echinochrome A (Ech A) on systemic changes using a rat model of preeclampsia. The results showed that an infusion of angiotensin II (Ang II) through an osmotic pump (1 μg/kg/min) on GD 8 increased systolic and diastolic
Huixing Cui +6 more
doaj +4 more sources
Echinochrome Prevents Sulfide Catabolism-Associated Chronic Heart Failure after Myocardial Infarction in Mice [PDF]
Marine Drugs, 2023 Abnormal sulfide catabolism, especially the accumulation of hydrogen sulfide (H2S) during hypoxic or inflammatory stresses, is a major cause of redox imbalance-associated cardiac dysfunction.
Xiaokang Tang +15 more
doaj +4 more sources
Carrageenans-Sulfated Polysaccharides from Red Seaweeds as Matrices for the Inclusion of Echinochrome [PDF]
Marine Drugs, 2017 The possibility of using different types of carrageenans (CRG) as matrixes for incorporating of echinochrome A (Ech) was investigated. Ech interacts with carrageenans and is incorporated into the macromolecular structure of the polysaccharide.
Viktoriya Davydova +2 more
exaly +4 more sources
Echinochrome A Prevents Diabetic Nephropathy by Inhibiting the PKC-Iota Pathway and Enhancing Renal Mitochondrial Function in db/db Mice [PDF]
Marine Drugs, 2023 Nguyen Quang Huy +2 more
exaly +4 more sources