Results 41 to 50 of about 552 (147)

Carrageenans and the Carrageenan-Echinochrome Complex as Anti-SARS-CoV-2 Agents. [PDF]

Int J Mol Sci
The diversity of structural types of carrageenans (CRGs)—sulfated polysaccharides of red algae—determines their different biological activities.
Krylova NV, Kravchenko AO, Likhatskaya GN, Iunikhina OV, Glazunov VP, Zaporozhets TS, Shchelkanov MY, Yermak IM.   +7 more
europepmc   +2 more sources

Interaction between nanomaterials and the innate immune system across evolution

Biological Reviews, Volume 98, Issue 3, Page 747-774, June 2023., 2023
ABSTRACT Interaction of engineered nanomaterials (ENMs) with the immune system mainly occurs with cells and molecules of innate immunity, which are present in interface tissues of living organisms. Immuno‐nanotoxicological studies aim at understanding if and when such interaction is inconsequential or may cause irreparable damage. Since innate immunity
Diana Boraschi, Laura Canesi, Damjana Drobne, Birgit Kemmerling, Annalisa Pinsino, Petra Prochazkova   +5 more
wiley   +1 more source

Pharmacokinetics of Marine-Derived Drugs

Marine Drugs, 2020
Marine organisms represent an excellent source of innovative compounds that have the potential for the development of new drugs. The pharmacokinetics of marine drugs has attracted increasing interest in recent decades due to its effective and potential ...
Alexander N. Shikov, Elena V. Flisyuk, Ekaterina D. Obluchinskaya, Olga N. Pozharitskaya   +3 more
doaj   +1 more source

THE EXTRACELLULAR RELEASE OF ECHINOCHROME [PDF]

Journal of General Physiology, 1946
A study was made of the diffusion of the red pigment echinochrome from the eggs of the sea urchin, Arbacia punctulata, into sea water. Unfertilized eggs retained their pigment, over periods of hours. Outward diffusion of pigment from unfertilized eggs normally is entirely negligible, or does not occur at all.
openaire   +3 more sources

Echinochrome A Release by Red Spherule Cells Is an Iron-Withholding Strategy of Sea Urchin Innate Immunity [PDF]

, 2017
Cellular immune defences in sea urchins are shared amongst the coelomocytes – a heterogeneous population of cells residing in the coelomic fluid (blood equivalent) and tissues. The most iconic coelomocyte morphotype is the red spherule cell (or amebocyte)
Claire McCulloch, Whalley, Tim, Joshua Betts, Coates, Christopher, Christopher J. Coates, McCulloch, Claire, Christopher Coates, Betts, Joshua, Tim Whalley   +8 more
core   +1 more source

Synthesis of Nano-Echinochrome extracted from Tubipora musica by Bacillus amyloliquefaciens CPFD8, and its potential medical applications as an anti-Alzheimer agent [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Natural products derived from marine organisms have emerged as promising sources of bioactive compounds with potential therapeutic applications. This study aimed to evaluate the antimicrobial, antioxidant, anti-inflammatory, and anti-Alzheimer properties
S.A. H. Hamdi, N.N. Mostafa, M.F. Fol, F. Medhat, I. Osama, N. Elsayed, S.H. Ismail, S.M. Korany, H. Sonbol, S. A. Alsaghir, M.N.Abd El-Ghany   +10 more
doaj   +1 more source

The Anti-Inflammatory Effect of Carrageenan/Echinochrom Complex at Experimental Endotoxemia. [PDF]

Int J Mol Sci, 2022
The anti-inflammatory effects of the CRG/Ech complex in LPS-induced endotoxemia were investigated in vivo in mice and in vitro in LPS-stimulated RAW 264.7 cells and peritoneal macrophages. The results indicated that the CRG/Ech complex suppressed the LPS-induced inflammatory response by reducing the production of ROS and NO in the macrophages ...
Yermak IM, Kravchenko AO, Khasina EI, Menchinskaya ES, Pislyagin EA, Sokolova EV, Likhatskaya GN, Aminin DL.   +7 more
europepmc   +3 more sources

Pigment Cell Differentiation in Sea Urchin Blastula-Derived Primary Cell Cultures

Marine Drugs, 2014
The quinone pigments of sea urchins, specifically echinochrome and spinochromes, are known for their effective antioxidant, antibacterial, antifungal, and antitumor activities. We developed in vitro technology for inducing pigment differentiation in cell
Natalya V. Ageenko, Konstantin V. Kiselev, Pavel S. Dmitrenok, Nelly A. Odintsova   +3 more
doaj   +1 more source

Pharmacological activity echinochrome a singly and consisting of baa "timarin" [PDF]

Biomeditsinskaya Khimiya, 2012
Pharmacological activity of echinochrome A (EchA) alone and in the biologically active additives (BAA) "Timarin", administered per os has been investigated on volunteers. EchA decreased serum glutatione (GSH) and increased catalase activity 1 h after treatment; catalase activity normalized, while GSH exceeded the initial level 3 h after the treatment ...
A A, Artiukov, A M, Popov, A V, Tsybul'skiĭ, O N, Krivoshapko, N V, Poliakova   +4 more
openaire   +2 more sources

Flaviviridae Viruses and Oxidative Stress: Implications for Viral Pathogenesis

Oxidative Medicine and Cellular Longevity, Volume 2019, Issue 1, 2019., 2019
Oxidative stress is induced once the balance of generation and neutralization of reactive oxygen species (ROS) is broken in the cell, and it plays crucial roles in a variety of natural and diseased processes. Infections of Flaviviridae viruses trigger oxidative stress, which affects both the cellular metabolism and the life cycle of the viruses ...
Zhenzhen Zhang, Liang Rong, Yi-Ping Li, Maria Isaguliants   +3 more
wiley   +1 more source