Isolation and Structure Determination of Echinochrome A Oxidative Degradation Products [PDF]
Molecules, 2020 Echinochrome A (Ech A, 1) is one of the main pigments of several sea urchin species and is registered in the Russian pharmacopeia as an active drug substance (Histochrome®), used in the fields of cardiology and ophthalmology.
Natalia P. Mishchenko +5 more
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Multiple Effects of Echinochrome A on Selected Ion Channels Implicated in Skin Physiology. [PDF]
Mar Drugs, 2023 Echinochrome A (Ech A), a naphthoquinoid pigment from sea urchins, is known to have anti-inflammatory and analgesic effects that have been suggested to be mediated by antioxidant activity and intracellular signaling modulation.
Kim SE +8 more
europepmc +3 more sources
Acetylcholinesterase Inhibitory Activity of Pigment Echinochrome A from Sea Urchin Scaphechinus mirabilis [PDF]
Marine Drugs, 2014 Echinochrome A (EchA) is a dark-red pigment of the polyhydroxynaphthoquinone class isolated from sea urchin Scaphechinus mirabilis. Acetylcholinesterase (AChE) inhibitors are used in the treatment of various neuromuscular disorders, and are considered as
Sung Ryul Lee +9 more
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Marine Drugs, 2019 Of late, researchers have taken interest in alternative medicines for the treatment of brain ischemic stroke, where full recovery is rarely seen despite advanced medical technologies.
Ran Kim +2 more
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Echinochrome A Improves Exercise Capacity during Short-Term Endurance Training in Rats
Marine Drugs, 2015 Echinochrome A (Echi A) improves mitochondrial function in the heart; however, its effects on skeletal muscle are still unclear. We hypothesized that Echi A administration during short-term exercise may improve exercise capacity. Twenty-four male Sprague-
Natalya Mishchenko +2 more
exaly +4 more sources
Antiherpetic Activity of Carrageenan Complex with Echinochrome A and Its Liposomal Form. [PDF]
Int J Mol Sci, 2022 Herpes simplex virus (HSV) infections, the incidence of which is still widespread throughout the world, are actualizing the search and development of new, more effective antiherpetic drugs. The development of multifunctional drug delivery systems, including liposome-based ones, has become a relevant and attractive concept in nanotechnology. The ability
Krylova NV +7 more
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Echinochrome pigment attenuates diabetic nephropathy in the models of type 1 and type 2 diabetes [PDF]
Сахарный диабет, 2016 Background. The main complication of diabetes mellitus is diabetic nephropathy in both types, which is a main reason for renal failure. Echinochrome substance present in sea urchin shells and spines and possesses high antioxidant activity.Aim.
Amel Mahmoud Soliman +2 more
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Activity of compounds containing echinochrome A against herpes simplex virus type 2 in vitro and in vivo [PDF]
Журнал микробиологии, эпидемиологии и иммунобиологии, 2019 The aim of the work was to study the activity of echinochrome A, a naphthoquinoid pigment from sea urchins, and its antioxidant composition against herpes simplex virus type 2 (HSV-2) in vitro and in vivo.Materials and methods.
N. V. Krylova +9 more
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Echinochrome A Treatment Alleviates Atopic Dermatitis-like Skin Lesions in NC/Nga Mice via IL-4 and IL-13 Suppression [PDF]
Marine Drugs, 2021 Atopic dermatitis (AD) is a chronic inflammatory skin disease in which skin barrier dysfunction leads to dryness, pruritus, and erythematous lesions. AD is triggered by immune imbalance and oxidative stress.
Elena Vasileva +2 more
exaly +3 more sources
ADJUVANT EFFECT OF TUBULAR IMMUNOSTIMULATING COMPLEXES MODIFIED BY ECHINOCHROME A, TOWARDS A PORE PROTEIN FROM YERSINIA PSEUDOTUBERCULOSIS [PDF]
Медицинская иммунология, 2014 . We investigated immunogenic properties of vaccine constructs based on lipid-saponin tubular immunostimulating complexes (TI-complexes), and an individual antigen, i.e., monomeric and trimeric forms of porin isolated from Yersinia ...
A. V. Tsybulsky +6 more
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