Results 31 to 40 of about 915 (185)

Sea Urchin Pigments: Echinochrome A and Its Potential Implication in the Cytokine Storm Syndrome [PDF]

open access: yesMarine Drugs, 2021
Background: Echinochrome A (EchA) is a pigment from sea urchins. EchA is a polyhydroxylated 1,4-naphthoquinone that contains several hydroxyl groups appropriate for free-radical scavenging and preventing redox imbalance. EchA is the most studied molecule
Tamara Rubilar   +3 more
doaj   +2 more sources

PHNQ from Evechinus chloroticus Sea Urchin Supplemented with Calcium Promotes Mineralization in Saos-2 Human Bone Cell Line [PDF]

open access: yesMarine Drugs, 2020
Polyhydroxylated naphthoquinones (PHNQs), known as spinochromes that can be extracted from sea urchins, are bioactive compounds reported to have medicinal properties and antioxidant activity.
Yakun Hou   +9 more
doaj   +2 more sources

Multiple Effects of Echinochrome A on Selected Ion Channels Implicated in Skin Physiology [PDF]

open access: yesMarine Drugs, 2023
Echinochrome A (Ech A), a naphthoquinoid pigment from sea urchins, is known to have anti-inflammatory and analgesic effects that have been suggested to be mediated by antioxidant activity and intracellular signaling modulation.
Sung Eun Kim   +8 more
doaj   +2 more sources

Echinochrome pigment attenuates diabetic nephropathy in the models of type 1 and type 2 diabetes

open access: diamondСахарный диабет, 2016
Background. The main complication of diabetes mellitus is diabetic nephropathy in both types, which is a main reason for renal failure. Echinochrome substance present in sea urchin shells and spines and possesses high antioxidant activity.Aim.
Amel Mahmoud Soliman   +2 more
doaj   +3 more sources

Isolation and Structure Determination of Echinochrome A Oxidative Degradation Products [PDF]

open access: yesMolecules, 2020
Echinochrome A (Ech A, 1) is one of the main pigments of several sea urchin species and is registered in the Russian pharmacopeia as an active drug substance (Histochrome®), used in the fields of cardiology and ophthalmology.
Natalia P. Mishchenko   +5 more
doaj   +3 more sources

Activity of compounds containing echinochrome A against herpes simplex virus type 2 in vitro and in vivo

open access: diamondЖурнал микробиологии, эпидемиологии и иммунобиологии, 2019
The aim of the work was to study the activity of echinochrome A, a naphthoquinoid pigment from sea urchins, and its antioxidant composition against herpes simplex virus type 2 (HSV-2) in vitro and in vivo.Materials and methods.
N. V. Krylova   +9 more
doaj   +3 more sources

THE EXTRACELLULAR RELEASE OF ECHINOCHROME [PDF]

open access: bronzeJournal of General Physiology, 1946
A study was made of the diffusion of the red pigment echinochrome from the eggs of the sea urchin, Arbacia punctulata, into sea water. Unfertilized eggs retained their pigment, over periods of hours. Outward diffusion of pigment from unfertilized eggs normally is entirely negligible, or does not occur at all.
Herbert Shapiro
openalex   +5 more sources

Evaluation of the cardiotoxicity of Echinochrome A using human induced pluripotent stem cell-derived cardiac organoids

open access: goldEcotoxicology and Environmental Safety
Echinochrome A (EchA), a marine-derived natural product, has shown promise in treating cardiovascular and inflammatory diseases due to its antioxidant and anti-inflammatory properties. However, its cardiac safety remains underexplored.
Su-Jin Lee   +11 more
doaj   +2 more sources

Echinochrome A Release by Red Spherule Cells Is an Iron-Withholding Strategy of Sea Urchin Innate Immunity [PDF]

open access: gold, 2018
Cellular immune defences in sea urchins are shared amongst the coelomocytes – a heterogeneous population of cells residing in the coelomic fluid (blood equivalent) and tissues. The most iconic coelomocyte morphotype is the red spherule cell (or amebocyte)
Betts, Joshua   +3 more
core   +3 more sources

Echinochrome A Protects against Ultraviolet B-induced Photoaging by Lowering Collagen Degradation and Inflammatory Cell Infiltration in Hairless Mice

open access: yesMarine Drugs, 2021
Echinochrome A (Ech A, 7-ethyl-2,3,5,6,8-pentahydroxy-1,4-naphthoquinone) has been known to exhibit anti-oxidative and anti-inflammatory effects. However, no study has been carried out on the efficacy of Ech A against skin photoaging; this process is ...
Jung Eun Seol, Sang Woo Ahn, Nammi Park
exaly   +3 more sources

Home - About - Disclaimer - Privacy