Echinochrome A Treatment Alleviates Fibrosis and Inflammation in Bleomycin-Induced Scleroderma [PDF]
Marine Drugs, 2021 Scleroderma is an autoimmune disease caused by the abnormal regulation of extracellular matrix synthesis and is activated by non-regulated inflammatory cells and cytokines.
Ki-Tae Ha +2 more
exaly +6 more sources
Echinochrome A Inhibits Melanogenesis in B16F10 Cells by Downregulating CREB Signaling. [PDF]
Mar Drugs, 2022 Excessive increase in melanin pigment in the skin can be caused by a variety of environmental factors, including UV radiation, and can result in spots, freckles, and skin cancer.
Choi MR +11 more
europepmc +6 more sources
Effects of Carrageenans on Biological Properties of Echinochrome [PDF]
Marine Drugs, 2018 Sea urchin pigment echinochrome A (Ech), a water-insoluble compound, is the active substance in the cardioprotective and antioxidant drug Histochrome® (PIBOC FEB RAS, Moscow, Russia).
Ekaterina V. Sokolova +6 more
doaj +4 more sources
Liposomal Form of the Echinochrome-Carrageenan Complex [PDF]
Marine Drugs, 2018 Inclusion of drugs in liposomes offers the potential for localized and sustained delivery to mucosal surfaces. The inclusion of the carrageenan matrix with echinochrome A ((Ech)—the active substance of the drug Histochrome) in liposomes was studied.
Irina M. Yermak +6 more
doaj +4 more sources
ANTIVIRAL AND ANTIOXIDANT ACTIVITY OF THE COMPOSITION OF COMPOUNDS BASED ON ECHINOCHROME A [PDF]
Журнал микробиологии, эпидемиологии и иммунобиологии, 2019 The aim of this study was to examine in vitro the antioxidant and antiviral activity of echinochrome A and echinochrome-based antioxidant composition against tick-borne encephalitis virus (TBEV) and herpes simplex virus type 1 (HSV-1).
N. V. Krylova +8 more
doaj +4 more sources
Marine Drugs, 2017 The possibility of using different types of carrageenans (CRG) as matrixes for incorporating of echinochrome A (Ech) was investigated. Ech interacts with carrageenans and is incorporated into the macromolecular structure of the polysaccharide.
Natalya Mishchenko +2 more
exaly +4 more sources
Echinochrome A Protects Mitochondrial Function in Cardiomyocytes against Cardiotoxic Drugs [PDF]
Marine Drugs, 2014 Echinochrome A (Ech A) is a naphthoquinoid pigment from sea urchins that possesses antioxidant, antimicrobial, anti-inflammatory and chelating abilities.
Seung Hun Jeong +10 more
doaj +5 more sources
Sea Urchin Pigments: Echinochrome A and Its Potential Implication in the Cytokine Storm Syndrome. [PDF]
Mar Drugs, 2021 Background: Echinochrome A (EchA) is a pigment from sea urchins. EchA is a polyhydroxylated 1,4-naphthoquinone that contains several hydroxyl groups appropriate for free-radical scavenging and preventing redox imbalance. EchA is the most studied molecule
Rubilar T +3 more
europepmc +3 more sources
Regulation of Inflammation-Mediated Endothelial to Mesenchymal Transition with Echinochrome a for Improving Myocardial Dysfunction. [PDF]
Mar Drugs, 2022 Endothelial–mesenchymal transition (EndMT) is a process by which endothelial cells (ECs) transition into mesenchymal cells (e.g., myofibroblasts and smooth muscle cells) and induce fibrosis of cells/tissues, due to ischemic conditions in the heart ...
Song BW +14 more
europepmc +3 more sources
Marine Drugs, 2014 Echinochrome A (Ech A) is a natural pigment from sea urchins that has been reported to have antioxidant properties and a cardio protective effect against ischemia reperfusion injury.
Nari Kim +2 more
exaly +4 more sources