Results 1 to 10 of about 13,575 (200)

Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice

PLoS Pathogens, 2021
Neonatal echovirus infections are characterized by severe hepatitis and neurological complications that can be fatal. Here, we show that expression of the human homologue of the neonatal Fc receptor (hFcRn), the primary receptor for echoviruses, and ...
Alexandra I Wells, Kenneth Kim, Emilie Branche   +2 more
exaly   +3 more sources

Cytolytic replication of echoviruses in colon cancer cell lines [PDF]

Virology Journal, 2011
Background Colorectal cancer is one of the most common cancers in the world, killing nearly 50% of patients afflicted. Though progress is being made within surgery and other complementary treatments, there is still need for new and more effective ...
Gullberg Maria, Jonsson Nina, Israelsson Stina, Lindberg A Michael   +3 more
doaj   +3 more sources

Investigation and successful control of an echovirus 11 outbreak in neonatal intensive care units

Pediatrics and Neonatology, 2020
Background: Echovirus 11 emerged as a predominant enterovirus strain and was associated with neonatal mortalities in Taiwan in 2018. We investigated an echovirus 11 outbreak in the neonatal intensive care units (NICUs) in a tertiary hospital in northern ...
Sheng-Yuan Ho, Cheng-Hsun Chiu, Yhu-Chering Huang   +2 more
exaly   +3 more sources

A novel post-mortem pathogen discovery program detects an outbreak of Echovirus E7: Uganda, 2022–2023 [PDF]

Frontiers in Microbiology
ObjectivesUtilizing post-mortem examination for routine monitoring of infectious diseases and pandemic preparedness is a common-sense, yet uncommon, public health measure.
Sonja L. Weiss, Sonja L. Weiss, Nicholas Bbosa, Nicholas Bbosa, Nicholas Bbosa, Gregory S. Orf, Gregory S. Orf, Michael G. Berg, Michael G. Berg, Deogratius Ssemwanga, Deogratius Ssemwanga, Sam Kalungi, Sam Kalungi, Stephen Balinandi, Maximillian Mata, Maximillian Mata, Henry Kyobe Bosa, Henry Kyobe Bosa, Henry Kyobe Bosa, Stella E. Nabirye, Joshua Buule, Tom Lutalo, Angela Havron, Angela Havron, Robert Downing, Mary A. Rodgers, Mary A. Rodgers, Francisco Averhoff, Francisco Averhoff, Gavin A. Cloherty, Gavin A. Cloherty, Pontiano Kaleebu, Pontiano Kaleebu   +32 more
doaj   +2 more sources

Tissue-resident macrophage and dendritic cells drive type I IFN immunity to enteroviruses in the liver. [PDF]

PLoS Pathogens
Enteroviruses are major causes of neonatal morbidity and mortality, with echovirus infections commonly associated with severe disease, including acute liver failure.
Emma Heckenberg, Jacob G Davis, Caitlin Hale, Carolyn B Coyne   +3 more
doaj   +2 more sources

Hemophagocytic lymphohistiocytosis in a neonate with enterovirus infection: Case report and literature review [PDF]

IDCases
Viruses are the most common organisms causing hemophagocytic lymphohistiocytosis (HLH), and enterovirus infection is the most frequently diagnosed virus infection in the newborn period.
Hua Hu, Shukun Yu, Jing Zhang, Hongping Zhang   +3 more
doaj   +2 more sources

Diversity of lake bacteria promotes human echovirus inactivation [PDF]

Applied and Environmental Microbiology
Human enteric viruses can remain infective in surface waters for extended periods of time, posing a public health risk. Microbial activity contributes to the inactivation of waterborne enteric viruses, but while individual bacteria–virus interactions ...
Andrii Romanenko, Hannes Peter, Josephine Meibom, Mark A. Borchardt, Tamar Kohn   +4 more
doaj   +2 more sources

Recent Molecular Epidemiology of Echovirus 11 Throughout North and West Africa Resulted in the First Identification of a Recombinant Strain from an Acute Flaccid Paralysis Case in West Africa [PDF]

Viruses
Echovirus 11 has emerged as a major public health concern, causing sepsis in neonates in many European countries in recent years. In Africa, especially West Africa, where resources and diagnostic capacities are limited, only sporadic cases have been ...
Ndack Ndiaye, Fatou Diène Thiaw, Adamou Lagare, Thérèse Sinare, Mohamed Lemine Diakité, Serigne Fallou Mbacké Ngom, Ousmane Kébé, Issifi Kollo Abdoulkader, Gassim Cissé, Mohamed Dia, Hermann Nodji Djimadoum, Christelle Ouedraogo Neya, Rakia Boubakar, Issaka Ouedraogo, Landoh Dadja Essoya, Ndongo Dia, Amadou Alpha Sall, Ousmane Faye, Martin Faye   +18 more
doaj   +2 more sources

Echovirus induces autophagy to promote viral replication via regulating mTOR/ULK1 signaling pathway

Frontiers in Immunology, 2023
Among enteroviruses, echovirus can cause severe illnesses in neonates or infants, with high morbidity and mortality. Autophagy, a central component of host defense mechanisms, can function against diverse infections. In the present study, we investigated
Chunchen Wu, Luzhi Zeng, Luzhi Zeng, Wenfu Yi, Yuanjiu Miao, Yihan Liu, Yihan Liu, Qiming Wang, Shi Liu, Guoping Peng, Zhenhua Zheng, Jianbo Xia   +11 more
doaj   +1 more source

Clinical, Laboratory, and Molecular Epidemiology of an Outbreak of Aseptic Meningitis Due to a Triple-Recombinant Echovirus in Ashburton, New Zealand

Viruses, 2022
Here, we describe a small enterovirus outbreak including nine cases of aseptic meningitis in a New Zealand hospital in 2017. Most patients had a lymphocytic predominance in the CSF, their length of stay was short, and there were no paediatric cases or ...
Meik Dilcher, Julia C. Howard, Simon C. Dalton, Trevor Anderson, Richard T. Clinghan, Anja M. Werno   +5 more
doaj   +1 more source