Results 21 to 30 of about 14,832 (257)
Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18
mBio, 2022 Virus-receptor interactions determine viral host range and tissue tropism. CD55 and human neonatal Fc receptor (FcRn) were found to be the binding and uncoating receptors for some of the echovirus-related enterovirus species B serotypes in our previous ...
Xiangpeng Chen +14 more
doaj +1 more source
Novel Synergistic Anti-Enteroviral Drug Combinations
Viruses, 2022 Background: Enterovirus infections affect people around the world, causing a range of illnesses, from mild fevers to severe, potentially fatal conditions. There are no approved treatments for enterovirus infections. Methods: We have tested our library of
Aleksandr Ianevski +7 more
doaj +1 more source
Hsp70 Is a Potential Therapeutic Target for Echovirus 9 Infection
Frontiers in Molecular Biosciences, 2020 Echovirus is an important cause of viral pneumonia and encephalitis in infants, neonates, and young children worldwide. However, the exact mechanism of its pathogenesis is still not well understood. Here, we established an echovirus type 9 infection mice
Yang Wang +8 more
doaj +1 more source
Echovirus 22 is an atypical enterovirus [PDF]
Journal of Virology, 1990 Although echovirus 22 (EV22) is classified as an enterovirus in the family Picornaviridae, it is atypical of the enterovirus paradigm, typified by the polioviruses and the coxsackie B viruses. cDNA reverse transcribed from coxsackievirus B3 (CVB3) RNA does not hybridize to genomic RNA of EV22, and conversely, cDNA made to EV22 does not hybridize to ...
B A, Coller +5 more
openaire +5 more sources
Current status of healthcare-associated enteroviral (non-polio) infections
Инфекция и иммунитет, 2020 Here we present the data on foreign research publications describing healthcare-associated enteroviral (nonpolio) infections (HAI) sought in the Worldwide Database for Nosocomial Outbreaks (Institut für Hygiene und Umweltmedizin ...
A. V. Alimov +4 more
doaj +1 more source
Therapeutics for fulminant hepatitis caused by enteroviruses in neonates
Frontiers in Pharmacology, 2022 Neonatal infection with nonpolio enteroviruses (EVs) causes nonspecific febrile illnesses and even life-threatening multiorgan failure. Hepatitis, which often results in hepatic necrosis followed by disseminated intravascular coagulopathy, is one of the ...
Li-Chiu Wang +6 more
doaj +1 more source
mBio, 2022 Enteroviruses are among the most common viral infectious agents of humans and cause a broad spectrum of mild-to-severe illness. Enteroviruses are transmitted primarily by the fecal-oral route, but the events associated with their intestinal replication ...
Alexandra I. Wells +2 more
doaj +1 more source
The Impact of Capsid Proteins on Virus Removal and Inactivation During Water Treatment Processes [PDF]
, 2015 This study examined the effect of the amino acid composition of protein capsids on virus inactivation using ultraviolet (UV) irradiation and titanium dioxide photocatalysis, and physical removal via enhanced coagulation using ferric chloride.
Abbaszadegan, Morteza A. +3 more
core +3 more sources
Internalization of Echovirus 1 in Caveolae [PDF]
Journal of Virology, 2002 ABSTRACT Echovirus 1 (EV1) is a human pathogen which belongs to the Picornaviridae family of RNA viruses. We have analyzed the early events of infection after EV1 binding to its receptor α2β1 integrin and elucidated the route by which EV1 gains access to the host cell. EV1 binding onto the cell
Varpu, Marjomäki +9 more
openaire +2 more sources
Integrin α2β1 in nonactivated conformation can induce focal adhesion kinase signaling. [PDF]
, 2017 Conformational activation of integrins is generally required for ligand binding and cellular signalling. However, we have previously reported that the nonactivated conformation of α2β1 integrin can also bind to large ligands, such as human echovirus 1 ...
Cheng, R Holland +5 more
core +2 more sources