Results 1 to 10 of about 8,426 (140)
FcRn Expression in Wildtype Mice, Transgenic Mice, and in Human Tissues
Biomolecules, 2018 Quantitative real-time PCR and Western blot methods were developed to assess neonatal Fc-receptor (FcRn) mRNA and protein expression in human FcRn transgenic mice, Swiss Webster mice, and in select human tissues. Additionally, FcRn turnover was evaluated
Joseph P Balthasar
exaly +3 more sources
Megalin Orchestrates FcRn Endocytosis and Trafficking
Cells, 2022 The neonatal Fc receptor (FcRn) is highly expressed in the renal proximal tubule and is important for the reclamation of albumin by cellular transcytosis to prevent its loss in the urine. The initial event of this transcellular transport mechanism is the
Eileen Dahlke +4 more
doaj +1 more source
The neonatal Fc receptor expression during macrophage differentiation is related to autophagy
Frontiers in Immunology, 2022 The neonatal Fc receptor (FcRn) plays a central role in recycling and biodistributing immunoglobulin G. FcRn is also involved in many physiological immune functions as well as pathological immune responses in cancer or autoimmune diseases.
Juliette Lamamy +8 more
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Frontiers in Microbiology, 2020 Transmissible gastroenteritis virus (TGEV) is a porcine intestinal coronavirus that causes fatal severe watery diarrhea in piglets. The neonatal Fc receptor (FcRn) is the only IgG transport receptor, its expression on mucosal surfaces is triggered upon ...
Shaoju Qian +16 more
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Characterization of the rabbit neonatal Fc receptor (FcRn) and analyzing the immunophenotype of the transgenic rabbits that overexpresses FcRn. [PDF]
PLoS ONE, 2012 The neonatal Fc receptor (FcRn) regulates IgG and albumin homeostasis, mediates maternal IgG transport, takes an active role in phagocytosis, and delivers antigen for presentation.
Ana Paula Catunda Lemos +9 more
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FcRn Expression in Endometrial Cancer and Its Association with Clinicopathologic Features
Diagnostics, 2023 Background: Endometrial cancer (EC) has robust molecular diagnostic evidence that correlates well with prognosis. In various types of cancers, FcRn has been identified as an early marker for prognosis.
Dae Hyun Song +5 more
doaj +1 more source
THE ROLE OF THE NEONATAL FC RECEPTOR IN THE UNCOATING OF ECHOVIRUSES AND COXSACKIEVIRUS A9
Вопросы вирусологии, 2019 The aim of this study was to determine the role of the human neonatal receptor for the Fc fragment of IgG (hFcRn) as a common uncoating cellular receptor for echoviruses and coxsackievirus A9 during infection of human rhabdomyosarcoma (RD) cells ...
P. S. Usoltseva +4 more
doaj +1 more source
Cell surface dynamics and cellular distribution of endogenous FcRn. [PDF]
PLoS ONE, 2017 A major role for FcRn is the salvage of pinocytosed IgG and albumin from a degradative fate in lysosomes. FcRn achieves this by binding IgG in a pH-dependent manner in acidic endosomes and recycling it to the plasma membrane to be released at neutral pH.
Lena D'Hooghe +3 more
doaj +1 more source
mAbs, 2020 The neonatal Fc receptor (FcRn) is a key membrane protein that plays an integral role in serum immunoglobulin (IgG) recycling, which extends the half-life of antibody.
Yue Sun +3 more
doaj +1 more source
Revista Brasileira de Prescrição e Fisiologia do Exercício, 2023 Várias intervenções têm sido propostas com a finalidade de atenuar os prejuízos motores decorrentes do Acidente Vascular Encefálico (AVE), incluindo os exercícios resistidos, entretanto, é incerto qual tipo de contração priorizar para esta população.
Liliane Araújo Guimarães +3 more
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