Results 121 to 130 of about 308,092 (299)

Preliminary Study of a Ninj1‐Loaded Bimodal Ultrasound/NIR Fluorescence Targeted Molecular Probe for Diagnosing Early‐Stage Inflammation in Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Coronary microvascular dysfunction (CMD) targeting remains a challenge for precise diagnosis. This work presents a dual‐modal nanoprobe (T‐IR780‐NBs) that combines ultrasound contrast with near‐infrared fluorescence. This technology utilizes proteomics‐derived antibodies that specifically localize to inflamed and injured cardiac tissue, enabling ...
Xiaohui Xu, Lina Guan, Baihetiya Tayier, Chen Yuan, Shangke Chen, Qi Shi, Yuming Mu   +6 more
wiley   +1 more source

Search for neutrinoless tau decays tau -> 3l and tau -> l K0S

, 2002
Neutrinoless tau-lepton decays into either three leptons (tau- -> l1- l2 l3) or one lepton and one K0S meson(tau- -> l- K0S) where lepton l means either an electron or muon, have been searched for using 48.6 fb^{-1} of data collected with the Belle ...
A. Yamaguchi, Abashian, Ahmad, Ahmad, Berends, Bliss, Borzumati, Brun, Chen, Cheng, Cvetic, Dedes, Ellis, Feldman, Fukuda, H. Hayashii, Hagiwara, Hayes, Hisano, Hisano, Hisano, Hisano, Ilakovac, Ilakovac, Jadach, Jadach, Jadach, Kim, Lee, Ma, Ma, Ma, Ma, Marciano, Masiero, T. Nagamine, Y. Yusa, Yue   +37 more
core   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Macroscopic quantum coherence in mesoscopic ferromagnetic systems

, 1999
In this paper we study the Macroscopic Quantum Oscillation (MQO) effect in ferromagnetic single domain magnets with a magnetic field applied along the hard anistropy axis.
A. Chiolero, A. Garg, A. Garg, A. Perelomov, B. Barbara, C. Sangregorio, D. D. Awschalom, D. D. Awschalom, D. D. Awschalom, D. Loss, D. Loss, E. Fradkin, E. M. Chudnovsky, F. C. Pu, I. V. Krive, J. M. Hernandez, J. M. Hernandez, J. Q. Liang, J. Q. Liang, J. Q. Liang, J. R. Friedman, J. V. Delft, J.-G. Zhou, L. D. Faddeev, L. Gunther, L. Thomas, M. Enz, M. Enz, N. Vernier, S. Coleman, S. Gider, S. P. Kou, S. S. Schweber, V. Yu. Golyshev, X. B. Wang, Y. Aharonov, Y. B. Zhang   +36 more
core   +1 more source

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

Advanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He, Lingxiao Zhang, Yue Xiong, Yu Wang, Yuqing Zeng, Dandan Su, Ran Wang, Ying Li, Hongbo Chen, Fang Cheng, Zhi Ping Xu   +10 more
wiley   +1 more source

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States

Advanced Healthcare Materials, EarlyView.
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao, Ao Zheng, Zhengyan Zhao, Qilin Li, Tianhao Wan, Tanjun Deng, Ying Zhang, Lingyan Cao, Lan Wu   +8 more
wiley   +1 more source

COVID 19 IMPLICATIONS ON CREDIT LOSS PROVISIONING RULES UNDER IFRS 9: PRO-CYCLICALITY CONCERNS

المجلة الدولية للأداء الاقتصادي
The objective of this paper is to analyse the procyclicality behavior of Expected Credit Loss (ECL) model introduced by IFRS 9, during the economic downturn due to the Covid 19 pandemic.
DJELIL Bilal, SAIDJ Faiz
doaj  

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Ultrasound‐Triggered Nanobubbles for Endothelial‐Targeted Drug Delivery in the Detection and Treatment of Doxorubicin‐Induced Cardiotoxicity

Advanced Healthcare Materials, EarlyView.
The DA/VTP‐NBs selectively recognized cardiac ECs damaged by DIC and achieved cell‐level targeted imaging. Then US‐triggered controlled release successfully enabled the release of DAPA within the DA/VTP‐NBs at the site of injury. This precise on‐demand drug release approach amplifies a series of localized therapeutic effects through the mtDNA‐mediated ...
Jun Zhang, Yi Ling, Xin Li, Deng Liu, Li Dong, Xuemei Chen, Yingxin Sun, Yongning Shang, Yanli Guo   +8 more
wiley   +1 more source

PM Eddy Current Loss Calculation Based on Magductance for FSPM Machine

IET Electric Power Applications
This paper proposes a novel model for calculating eddy current losses (ECL) in permanent magnets (PMs) using the principle of magductance. The focus is on integrating magductance elements into the 2D electromagnetic field finite element method (FEM ...
Jingxia Wang, Shicheng Cao, Wei Qin, Ming Cheng, Qingqing Yuan, Kun Xia, Wei Yu   +6 more
doaj   +1 more source