Results 81 to 90 of about 308,092 (299)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Comb-based WDM transmission at 10 Tbit/s using a DC-driven quantum-dash mode-locked laser diode

open access: yes, 2019
Chip-scale frequency comb generators have the potential to become key building blocks of compact wavelength-division multiplexing (WDM) transceivers in future metropolitan or campus-area networks.
Abderrahim Ramdane   +47 more
core   +3 more sources

RR Lyrae variables in M5 as a test of pulsational theory [PDF]

open access: yes, 1999
We present B and V CCD photometry for variables in the cluster central region, adding new data for 32 variables and giving suitable light curves, mean magnitudes and corrected colors for 17 RR Lyrae. Implementing the data given in this paper with similar
Caputo, F.   +3 more
core   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Identification and Ranking of Barriers to the Expected Credit Loss (ECL) Model Implementation in Iranian Banks Using the FAHP and WASPAS Technique [PDF]

open access: yesبررسی‌های حسابداری و حسابرسی, 2019
Objective: The purpose of this research is to identify and quantify the challenges of implementing the expected credit loss (ECL) model in Iranian banks. This model can identify the effects of defaults in earlier periods, which would reduce the volume of
Ali Rezaei   +2 more
doaj   +1 more source

Non-magnetic impurities in two- and three- dimensional Heisenberg antiferromagnets

open access: yes, 1996
In this paper we study in a large-S expansion effects of substituting spins by non-magnetic impurities in two- and three- dimensional Heisenberg antiferromagnets in a weak magnetic field.
G. Xiao   +12 more
core   +1 more source

Assessing the Impact of Modelling on the Expected Credit Loss (ECL) of a Portfolio of Small and Medium-sized Enterprises [PDF]

open access: yesUniversal Journal of Management, 2018
This paper studies the impact of the internal modelling on the calculation of expected credit loss in the framework of the international standard IFRS 9. Indeed, the probability of default of counterparty depends on the model used for the conception of the internal rating system.
Saâd Benbachir, Mohamed Habachi
openaire   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

ERDNN: Error-Resilient Deep Neural Networks With a New Error Correction Layer and Piece-Wise Rectified Linear Unit

open access: yesIEEE Access, 2020
Deep Learning techniques have been successfully used to solve a wide range of computer vision problems. Due to their high computation complexity, specialized hardware accelerators are being proposed to achieve high performance and efficiency for deep ...
Muhammad Salman Ali   +6 more
doaj   +1 more source

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