Results 41 to 50 of about 435,619 (292)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

EifFE-L meets ECLIPSE: an integrated open source e-learning environment

Je-LKS: Journal of E-Learning and Knowledge Society, 2009
This work reports on the process of integration of the EifFE-L open source e-learning platform within the Eclipse open source development platform, with the aim to create an open framework for both distance education and knowledge management. The fusion
Giovanni Adorni, Mauro Coccoli, Lidia Stanganelli, Paolo Maresca   +3 more
doaj   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Spectropolarimetry and Modeling of the Eclipsing T Tauri Star KH 15D

, 2003
KH 15D is a strongly variable T Tauri star in the young star cluster NGC 2264 that shows a decrease in flux of 3.5 magnitudes lasting for 18 days and repeating every 48 days.
Aaron J. Barth, Antonucci R., Bouvier J., Brown J. C., David Charbonneau, Eric Agol, Hong S. S., Mekkaden M. V., Sebastian Wolf, Voshchinnikov N. V., Wiscombe W. J.   +10 more
core   +1 more source

Evidence for a planetary mass third body orbiting the binary star KIC 5095269 [PDF]

, 2017
In this paper, we report the evidence for a planetary mass body orbiting the close binary star KIC 5095269. This detection arose from a search for eclipse timing variations among the more than 2,000 eclipsing binaries observed by Kepler.
Carter, B., Getley, A. K., King, R., O'Toole, S.   +3 more
core   +3 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

La Televisión Digital Terrestre en el Ecuador es interactiva

Revista Eídos, 2012
El presente artículo, es una introducción a la situación actual de la TV Digital Terrestre en el Ecuador, considerando los factores políticos y técnicos que llevaron a la decisión de adoptar el estándar ISDB-Tb. para reemplazar a la televisión analógica,
Darwin Alulema
doaj   +1 more source

ANALYSIS OF SPHERICAL ASTRONOMY ALGORITHMS FOR PREDICTING THE SOLAR ECLIPSE BY W.M. SMART

Al-Hilal, 2022
A solar eclipse is an unusual natural occurrence. Muslims used the phenomenon of a solar eclipse as the season for prayer, which was only carried out during a solar eclipse from early in the phenomenon until the end.
Fiki Nuafi Qurrota Aini, Ahmad Luqman Hakim   +1 more
doaj   +1 more source

Changes in Polarization Position Angle across the Eclipse in the Double Pulsar System [PDF]

, 2012
We investigate the changes in polarization position angle in radiation from pulsar A around the eclipse in the Double Pulsar system PSR J0737-3039A/B at the 20 cm and 50 cm wavelengths using the Parkes 64-m telescope. The changes are ~2\sigma\ during and
Burgay, M., Camilo, F., Kramer, M., Manchester, R. N., Melrose, D. B., Stairs, I. H., Yuen, R.   +6 more
core   +1 more source