Results 241 to 250 of about 324,854 (299)

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

Advanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng, Cinzia Esposito, Andrej Benjak, Matthias S. Matter, Miriam Cieri, Camilla De Carlo, Philipp Sedlaczek, Fabian Haak, Mattia Marinucci, Gabriel Fridolin Hess, Otto Kollmar, Mairene Coto‐Llerena, Luca Di Tommaso, Visar Vela, Lukas Bubendorf, Luigi M. Terracciano, Charlotte K. Y. Ng, Salvatore Piscuoglio   +17 more
wiley   +1 more source

Integrating Extracellular Matrix Dynamics and Membrane-Associated Signaling: The Role of Clusterin-LRP1 Network in Cancer Cell Migration and Tumor Progression. [PDF]

Cancers (Basel)
Ciringione A, Rizzi F, Mangani S, Piperigkou Z, Karamanos N.   +4 more
europepmc   +1 more source

Extracellular matrix-driven patient stratification and network modeling reveal distinct molecular grades with potential clinical implications. [PDF]

NPJ Syst Biol Appl
Dansık A, Sarıca S, Öztürk E, Tuncbag N.   +3 more
europepmc   +1 more source

MITF-Driven melanoma plasticity as a core mechanism of therapy resistance: integrating microenvironmental signaling, mechanotransduction, and metabolic reprogramming. [PDF]

Cell Cycle
Kisielewska M, Suwała S, Drąg-Zalesińska M, Rembiałkowska N.   +3 more
europepmc   +1 more source

Role of collagen VI and IX in mechanotransduction in the cartilage microenvironments: A multiscale in silico examination. [PDF]

J Orthop Translat
Adouni M, Gouissem A, Dhaher YY.
europepmc   +1 more source

Ubiquitination in intervertebral disc degeneration: from mechanisms to potential therapeutic strategies. [PDF]

J Orthop Translat
Liu X, Kang X.
europepmc   +1 more source

ECM proteoglycans

Reactome - a curated knowledgebase of biological pathways, 2013
openaire   +1 more source

Electronic health record mining reveals effects of patient immune status on clinical outcomes of biomaterial implantation following skeletal muscle damage.

Biomater Sci
Sharma S, Horton I, Josyula A, Sadtler K.   +3 more
europepmc   +1 more source