Results 281 to 290 of about 469,615 (331)
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Extracellular Matrix (ECM) and Fibrosis in Adipose Tissue: Overview and Perspectives
Comprehensive Physiology, 2023Fibrosis in adipose tissue is a major driver of obesity‐related metabolic dysregulation. It is characterized by an overaccumulation of extracellular matrix (ECM) during unhealthy expansion of adipose tissue in response to over nutrition. In obese adipose‐
K. Sun, Xin Li, Philipp E. Scherer
semanticscholar +1 more source
Viscoelastic Cell Microenvironment: Hydrogel‐Based Strategy for Recapitulating Dynamic ECM Mechanics
Advanced Functional Materials, 2021The native extracellular matrix (ECM) generally exhibits dynamic mechanical properties and displays time‐dependent responses to deformation or mechanical loading, in terms of viscoelastic behaviors (e.g., stress relaxation and creep).
Yu-Fei Ma +7 more
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ECM in Differentiation: A Review of Matrix Structure, Composition and Mechanical Properties
Annals of Biomedical Engineering, 2019Amrinder Nain, Abinash Padhi
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, 2013 In 3D culture, our model allows for the investigation of a cross section of the system and the cells that are immersed in ECM. In 2D, the contact region of the ECM and the cell is a line that surrounds the cell; therefore, an enclosed curve (or ring) can
Mohammad Azimi (343458) +2 more
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ACS Nano, 2022
Implanting a 3D printing scaffold is an effective therapeutic strategy for personalized bone repair. As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent
Kun Liu +10 more
semanticscholar +1 more source
Implanting a 3D printing scaffold is an effective therapeutic strategy for personalized bone repair. As the key factor for the success of bone tissue engineering, the scaffold should provide an appropriate bone regeneration microenvironment and excellent
Kun Liu +10 more
semanticscholar +1 more source
ECM stiffness-tuned exosomes drive breast cancer motility through thrombospondin-1.
Biomaterials, 2021Breast cancer progression features ECM stiffening due to excess deposition and crosslinking of collagen, which dramatically influence tumor behaviour and fate. The mechanisms by which extracellular matrix (ECM) stiffening drives breast cancer invasion is
Siddharth Patwardhan +3 more
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Emerging roles of ECM remodeling processes in cancer.
Seminars in Cancer Biology, 2020Extracellular matrix (ECM) plays a central and dynamic role in the creation of tumor microenvironment. Herein we discuss the emerging biophysical and biochemical aspects of ECM buildup and proteolysis in cancer niche formation.
V. Mohan, Alakesh Das, I. Sagi
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Extracellular matrix (ECM) stiffness and degradation as cancer drivers
Journal of Cellular Biochemistry, 2018Alteration in the density and composition of extracellular matrix (ECM) occurs in tumors. The alterations toward both stiffness and degradation are contributed to tumor growth and progression.
M. Najafi, B. Farhood, K. Mortezaee
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ECM-mimicking composite hydrogel for accelerated vascularized bone regeneration
Bioactive MaterialsBioactive hydrogel materials have great potential for applications in bone tissue engineering. However, fabrication of functional hydrogels that mimic the natural bone extracellular matrix (ECM) remains a challenge, because they need to provide ...
Guanglong Li +10 more
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Decellularized ECM-derived bioinks: Prospects for the future.
Methods, 2020Decellularization aims to remove cells from tissue ultrastructure while preserving the mechanical and biological properties, which makes the decellularized extracellular matrix (dECM) an appropriate scaffold for tissue engineering applications.
F. Kabirian, M. Mozafari
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