Results 71 to 80 of about 49,480 (260)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Associations between challenging parenting behavior and creative tendencies of children: the chain mediating roles of positive emotion and creative self-efficacy

Frontiers in Psychology
BackgroundParenting behavior has been reported to be closely associated with children’s creativity, yet the association between challenging parenting behavior and children’s creative tendencies, as well as the potential mechanisms connecting the two ...
Dasheng Shi, Yidi Wang, Ruining Jin, Lin Chu   +3 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Study of Commercial Law (Economic Law) and Environmental Law related to Plastic Waste Import in Indonesia

Journal of Social Research
Effective waste management is essential for reducing Indonesia’s dependence on imported waste. However, inadequate domestic waste management systems have made it difficult for the country to meet industrial raw material needs independently. One of the industries significantly affected is the paper industry, which requires both long and short fibers for
Nomensen Freddy Siahaan, Agustina Wati
openaire   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Methodical approach to the choice of a business management strategy within the framework of a change in commercial activities

Business: Theory and Practice
The main purpose of the article is the formation of new strategies in business management with changes in commercial activities. The object of the study is the system of commercial activity and possible changes in it.
Farouq Ahmad Faleh Alazzam, Bassam Mustafa Abdel-Rahman Tubishat, Oksana Storozhuk, Olga Poplavska, Zinaida Zhyvko   +4 more
doaj   +1 more source

The scope of economic relations in the legaland legislative regulation

Проблеми Законності, 2016
Problem setting. Ensuring legal regulation of social and economic relations is very topical issue not only current socio-economic, but also social and political life of the state.
Юлія Остапенко
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Rethinking Ethiopian Secured Transactions Law through comparative perspective: lessons from the Uniform Commercial Code of the US

Mizan Law Review, 2017
Various countries have reformed their secured transaction laws recognizing the significance of modern secured transactions law in enhancing access to credit and economic development.
Asress Adimi Gikay
doaj   +1 more source