Results 121 to 130 of about 213,305 (310)

Board Networks and Corporate Carbon Emissions: A Cross‐Country Analysis of Causal Effects

Business Strategy and the Environment, EarlyView.
ABSTRACT This study examines whether board networks influence corporate carbon emissions and the strategic pathways through which firms decarbonize. Using a sample of 1952 firms across 48 countries from 2003 to 2020, we employ dynamic stacked regressions that exploit exogenous carbon‐regulation shocks affecting firms connected through shared third ...
Katarzyna Burzynska, Sara Jonsson, Lu Liu, Michał Dzieliński   +3 more
wiley   +1 more source

Modeling the budget impact of long-acting injectable paliperidone palmitate in the treatment of schizophrenia in Japan

ClinicoEconomics and Outcomes Research, 2015
Jörg Mahlich,1,2 Masamichi Nishi,3 Yoshimichi Saito11Health Economics, Janssen Pharmaceutical KK, Tokyo, Japan; 2Düsseldorf Institute for Competition Economics, University of Düsseldorf, Düsseldorf, Germany; 3Pricing, Janssen ...
Mahlich J, Nishi M, Saito Y
doaj  

Advancing Theory and Practice Concerning CO2e Emissions: A Time‐Based Tool for Organisations

Business Strategy and the Environment, EarlyView.
ABSTRACT Although organisations are increasingly scrutinised on their CO2e emissions, economic growth is frequently encouraged. Eco‐efficiency–based initiatives—‘doing more with less’—could be a solution. The problem is that many organisations (e.g., smaller enterprises without access to specialist knowledge) have difficulties in gauging the impact of ...
Andrea Stevenson Thorpe, Frank Figge
wiley   +1 more source

Health Biotechnology Innovation for Social Sustainability -A Perspective from China [PDF]

, 2011
China is not only becoming a significant player in the production of high-tech products, but also an increasingly important contributor of ideas and influence in the global knowledge economy.
Chen, Yantai, Ely, Adrian
core   +1 more source

Versatile Palladium‐Catalyzed C‐H Arylation of Fluoroarenes with 2‐Chloropyridine Derivatives

Chemistry – A European Journal, EarlyView.
Direct C─H arylation of fluoroarenes with 2‐chloropyridines is enabled by a simple Pd/SPhos system in isopropyl acetate. The method uses inexpensive reactants and shows broad scope and high yields. DFT computations explain reactivity and selectivity.
Federico Belnome, Péter P. Fehér, András Stirling, Csongor G. Németh, Tamás Hergert, György M. Keserű, Péter Ábrányi‐Balogh   +6 more
wiley   +1 more source

Bayesian Optimization of Solvent‐Free Thermal Amidation via Reactive Extrusion

Chemistry – A European Journal, EarlyView.
Thermal amidation between a carboxylic acid and an amine was successfully conducted in an extruder in the absence of solvent, coupling agent, or catalyst, relying on an adapted Bayesian Optimization protocol. Active pharmaceutical ingredient moclobemide was synthesized on a larger scale, achieving excellent yield and low Process Mass Intensity (PMI ...
Matthieu Lavayssiere, Xavier Bantreil, Frédéric Lamaty   +2 more
wiley   +1 more source

Persistence with biologic agents for the treatment of rheumatoid arthritis in Japan

Patient Preference and Adherence, 2016
Jörg Mahlich,1,2 Rosarin Sruamsiri1,3 1Health Economics, Janssen Pharmaceutical KK, Tokyo, Japan; 2Düsseldorf Institute for Competition Economics (DICE), University of Düsseldorf, Düsseldorf, Germany; 3Center of Pharmaceutical ...
Mahlich J, Sruamsiri R
doaj  

A Methodology to Integrate Closed‐Cycle Heat Pumps into Batch Distillation Columns

Chemie Ingenieur Technik, EarlyView.
Batch distillation often cannot use vapor recompression due to contamination risks in food and pharma. This study proposes a design for integrating closed‐loop heat pumps using natural fluids. Results show significant energy savings, offering a sustainable alternative to traditional setups.
Philipp Dorn, Michael Libuda, Thomas Meyer, Christian Hoffmann, Jens‐Uwe Repke, Stefan Elbel   +5 more
wiley   +1 more source

Development of a Mechanically Regenerating Desublimator for Freeze‐Drying Systems in the Food Industry

Chemie Ingenieur Technik, EarlyView.
Thermal defrosting limits desublimator efficiency in freeze‐drying. This review and case study compares thermal versus mechanical regeneration, links frost properties and external heat transfer to energy demand, and summarizes pilot‐scale scraping results enabling single‐unit, continuous lyophilization.
Moritz Krummenacher, Mirko Kleingries, Edgar Zimmer, Roman Blättler   +3 more
wiley   +1 more source

Discontinuing Long‐Term Denosumab in Treating Fragile Bone: Why, for Whom, and How?

Clinical Pharmacology &Therapeutics, EarlyView.
Discontinuation of denosumab (Dmab) may be necessary due to adverse events or an unfavorable long‐term risk–benefit profile. However, accumulating evidence demonstrates pronounced rebound phenomena after withdrawal, most notably a marked increase in multiple vertebral fractures, and, in some reports, elevated mortality.
Ko‐Hsiu Lu, Renn‐Chia Lin, Ing‐Lin Chang, Shau‐Huai Fu, Meng‐Ying Tsai, Shun‐Fa Yang   +5 more
wiley   +1 more source