Results 141 to 150 of about 213,305 (310)

Patient‐Reported Outcomes with Selpercatinib Among Patients with RET Fusion–Positive Non‐Small Cell Lung Cancer in the Phase I/II LIBRETTO‐001 Trial

The Oncologist, EarlyView., 2021
Abstract Background LIBRETTO‐001 is an ongoing, global, open‐label, phase I/II study of selpercatinib in patients with advanced or metastatic solid tumors. We report interim patient‐reported outcomes in patients with RET fusion–positive non‐small cell lung cancer (NSCLC).
Anna Minchom, Aaron C. Tan, Erminia Massarelli, Vivek Subbiah, Valentina Boni, Bruce Robinson, Lori J. Wirth, Lisa M. Hess, Min‐Hua Jen, Jennifer Kherani, Elizabeth Olek, Caroline E. McCoach   +11 more
wiley   +1 more source

Dual‐Stabilized Single‐Site Fe(II) for Catalytic Conversion of CO2 to Propiolic Acid Under Ambient Condition

EcoEnergy, EarlyView.
We develop a highly cost‐effective heterogeneous catalyst for efficient CO2 conversion to propiolic acid under mild conditions via a nano‐confined approach with porous MIL support. ABSTRACT Efficient conversion of carbon dioxide to organics has been a promising outlet for value‐added carbon dioxide consumption.
Bin Lei, Zhenzhen Zhou, Xiao Liu, Bo Li, Wenyuan Wang, Jian‐Gong Ma, Peng Cheng   +6 more
wiley   +1 more source

Patient‐Reported Outcomes with Selpercatinib Treatment Among Patients with RET‐Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO‐001 Trial

The Oncologist, EarlyView., 2021
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth, Bruce Robinson, Valentina Boni, Daniel S.W. Tan, Caroline McCoach, Erminia Massarelli, Lisa M. Hess, Min‐Hua Jen, Jennifer Kherani, Elizabeth Olek, Vivek Subbiah   +10 more
wiley   +1 more source

Pharmaceutical policy and health economics

Folia Pharmacologica Japonica, 2013
Hiroaki, Kakihara, Yoko, Ibuka, Xinxin, Ma   +2 more
openaire   +3 more sources

Recent Advances in Photocatalytic Urea Synthesis via C−N Coupling From C/N‐Containing Species: A Mini Review

EcoEnergy, EarlyView.
This review systematically compares photocatalytic urea synthesis from various C (CO2, CO, CH3OH) and N (N2, NH3, NO3−) sources. It highlights C–N coupling mechanisms, key challenges, and future directions, offering a framework to guide rational catalyst design for sustainable, solar‐driven urea production.
Bo Ding, Jicheng Chen, Hongji Liang, Xiang Yu, Wensheng Zhang, Dongxue Han   +5 more
wiley   +1 more source

Defect‐Engineered SrTiO3‐x for Flexoelectric‐Dominated Catalysis

EcoEnergy, EarlyView.
Defect‐engineered SrTiO3‐x nanoparticles with enhanced flexoelectricity efficiently degrade pollutants and produce hydrogen under ultrasound‐driven flexocatalysis. This materials–engineering approach offers a scalable pathway for combining environmental remediation and renewable energy applications. ABSTRACT Flexocatalysis provides an alternative route
Yu‐Chun Huang, Yue Jiang, Haotian Wen, Yunlong Sun, Hongyang Ma, Suchen Huang, Yating Ran, Zizheng Song, Xueqing Fang, Zekun Dong, Peiyuan Guan, Chenlu Jiang, Catherine Stampfl, Zibin Chen, Shery L. Y. Chang, Pramod Koshy, Danyang Wang   +16 more
wiley   +1 more source

Insights to Industrial Electrocatalytic Sulfide Oxidation: Electrode Fabrication, System Engineering, and High‐Value Product Acquisition

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This review summarizes recent advances in electrocatalytic sulfide oxidation (SOR), focusing on catalyst design strategies, reaction system engineering, and pathways for high‐value product generation. The roles of different reduced sulfur species (S2−, HS−, H2S) under various industrial conditions are highlighted, along with approaches to enhance ...
Zhongyuan Wang, Yinxi Han, Yufei Zhang, Jinghuan Chen, Jiade Wang   +4 more
wiley   +1 more source

Learning Networks Drive Environmental Innovation: Evidence From Fourth‐Stage Purification Diffusion

Environmental Policy and Governance, EarlyView.
ABSTRACT Contaminants of emerging concern, including pharmaceuticals and industrial chemicals, threaten water quality globally. In the European Union (EU), until the adoption of the revised Urban Wastewater Treatment Directive in 2024, a regulatory gap had left the member states and the municipalities in them without binding removal standards ...
Simon Bulian, Jale Tosun, Katrina Smith Korfmacher, Theresa Baur   +3 more
wiley   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Consumer preferences for the development of new emulsion products based on vegetable and animal fats. [PDF]

PLoS One
Kowalska M, Woźniak M, Golec K, Zbikowska A, Szakiel J, Turek P.   +5 more
europepmc   +1 more source