Results 41 to 50 of about 61,370 (255)

Global climate change adaptation priorities for biodiversity and food security. [PDF]

PLoS ONE, 2013
International policy is placing increasing emphasis on adaptation to climate change, including the allocation of new funds to assist adaptation efforts.
Lee Hannah, Makihiko Ikegami, David G Hole, Changwan Seo, Stuart H M Butchart, A Townsend Peterson, Patrick R Roehrdanz   +6 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source

Conserving key coastal areas for mangrove expansion and eco-tourism secures ecosystem services under sea-level rise

npj Ocean Sustainability
Blue carbon nature-based solutions (NbS) can mitigate climate change through carbon sequestration and storage, and support climate change adaptation and resilience by supplying ecosystem benefits.
Kostantinos A. Stamoulis, Simon J. Pittman, Jade M. S. Delevaux, Marina Antonopoulou, Stephen Carpenter, Rashyd Zaaboul, Aaron C. H. Chow, Himansu S. Das, Daniel Mateos-Molina   +8 more
doaj   +1 more source

Ecosystem-based adaptation practices for smallholder farmers’ climate resilience: perceived effectiveness and co-benefit importance in Mabalane District-Mozambique

Frontiers in Agronomy
Ecosystem-based adaptation practices among smallholder farmers in drought-prone areas provides a positive response strategy to the increasing challenges posed by climate change, particularly declining crop yield under dry spells condition.
Claudius Patrick Waran, Claudius Patrick Waran, Claudius Patrick Waran, Jaime Carlos Macuácua, Nicia Giva   +4 more
doaj   +1 more source

Pastoralism and ecosystem‐based adaptation in Kenyan Masailand

International Journal of Climate Change Strategies and Management, 2013
PurposeThe purpose of this paper is to assess the potential for pastoral communities inhabiting Kenyan Masailand to adapt to climate change using conservancies and payments for ecosystem services.Design/methodology/approachMultiple methods and data sources were used, comprising: a socio‐economic survey of 295 households; informal interviews with ...
Osano, P.M., Said, Mohammed Yahya, Leeuw, Jan de, Moiko, S.S., Kaelo, D.O., Schomers, S., Birner, R., Ogutu, Joseph O.   +7 more
openaire   +3 more sources

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

NFDI MatWerk Ontology (MWO): A BFO‐Compliant Ontology for Research Data Management in Materials Science and Engineering

Advanced Engineering Materials, EarlyView.
This article presents the NFDI‐MatWerk Ontology (MWO), a Basic Formal Ontology‐based framework for interoperable research data management in materials science and engineering (MSE). Covering consortium structures, research data management resources, services, and instruments, MWO enables semantic integration, Findable, Accessible, Interoperable, and ...
Hossein Beygi Nasrabadi, Ebrahim Norouzi, Kostiantyn Hubaiev, Jörg Waitelonis, Harald Sack   +4 more
wiley   +1 more source