Results 61 to 70 of about 15,455 (259)

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

Advanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao, Zunlei Gong, Chuke Chen, Hui Yu, Yu Cai, Can Liu, Hongkai Huang, Ying Li, Jinyuan Guan, Le Wang, Chengyun Ning, Guoxin Tan, Lei Zhou   +12 more
wiley   +1 more source

Modeling the Dynamics of Multispecies Fisheries: A Case Study in the Coastal Water of North Yellow Sea, China

Frontiers in Marine Science, 2020
Ecosystem models have been developed for detecting community responses to fishing pressure and have been widely applied to predict the ecological effects of fisheries management.
Jia Wo, Chongliang Zhang, Xindong Pan, Binduo Xu, Ying Xue, Yiping Ren, Yiping Ren   +6 more
doaj   +1 more source

Beyond Probiotics: Postbiotics for Healthy Aquaculture

Advanced Science, EarlyView.
This critical review assesses limitations of probiotics and proposes postbiotics, preparations of inanimate microorganisms and their metabolites, as a more stable, controlled, and biosafe formulation. Postbiotics offer significant advantages during industrial aquafeed production and storage. However, their practical implementation is currently hindered
Michael Leonidas Chikindas, Delin Xu, Igor V. Popov, Kayque Ordonho Carneiro, Nilufar Arashovna Elova, Gullola Amirovna Bekmurodova, Dildora Amindjanovna Amirsaidova, Astghik Pepoyan, Shakhlo Mirjamalovna Miralimova, Oleg V. Mitrokhin, Liubov S. Sichel, John Tagg, Svetoslav Dimitrov Todorov   +12 more
wiley   +1 more source

Future Ocean Observations to Connect Climate, Fisheries and Marine Ecosystems

Frontiers in Marine Science, 2019
Advances in ocean observing technologies and modeling provide the capacity to revolutionize the management of living marine resources. While traditional fisheries management approaches like single-species stock assessments are still common, a global ...
Jörn O. Schmidt, Steven J. Bograd, Haritz Arrizabalaga, José L. Azevedo, Steven J. Barbeaux, John A. Barth, Tim Boyer, Stephanie Brodie, Juan José Cárdenas, Scott Cross, Jean-Noël Druon, Agneta Fransson, Jason Hartog, Elliott L. Hazen, Alistair Hobday, Michael Jacox, Michael Jacox, Johannes Karstensen, Sven Kupschus, Jon Lopez, Lauro A. S.-P. Madureira, José E. Martinelli Filho, Patricia Miloslavich, Patricia Miloslavich, Catarina P. Santos, Kylie Scales, Sabrina Speich, Matthew B. Sullivan, Amber Szoboszlai, Desiree Tommasi, Desiree Tommasi, Douglas Wallace, Stephani Zador, Paulo Antônio Zawislak   +33 more
doaj   +1 more source

A Recyclable and Biodegradable High‐Performance Piezoelectric Nanogenerator for Self‐Powered Biosensing and Assistive Human‐Machine Interaction

Advanced Science, EarlyView.
By exploiting multiscale hydrogen‐bonding interactions between HFPD and TOCNF, the composite simultaneously achieves a high piezoelectric coefficient (14.0 pC·N−1), outstanding flexibility (100 000 bending cycles), water‐assisted recyclability, excellent biodegradability, and sensitive wearable/implantable sensing for motion, speech, and Morse code ...
Tingshuai Luo, Tian Xiao, Luyu Zhang, Bailang Zhang, Shengchang Lu, He Xiao, Jianguo Li, Kai Liu, Chaoji Chen, Hui Wu   +9 more
wiley   +1 more source

Historical ecosystem models can serve as a baseline for indicator-based assessment: the North Sea

Frontiers in Marine Science
Knowledge of past ecosystems is essential to understand how marine ecosystems have changed under human pressure. This understanding is critical for the effective management of marine ecosystems today. However, there has been limited effort to investigate
İsmet Saygu, İsmet Saygu, Ruth H. Thurstan, Callum Roberts, Zoe Heard, Ekin Akoglu, Ekin Akoglu, Paul R. Halloran   +7 more
doaj   +1 more source

Ecosystem-based fisheries management: An Australian perspective

Aquatic Living Resources, 2005
The terms ‘ecosystem-based fisheries management’, ‘ecosystem-based management’ and ‘ecosystem approach to fisheries’ have recently entered the vernacular of fisheries management. Examination of contemporary guidelines and proposals for such an approach illustrates that ecosystem-based fisheries management is, for all intents and purposes, a re ...
James P. Scandol, Michael G. Holloway, Philip J. Gibbs, Karen L. Astles   +3 more
openaire   +1 more source

Ammonification Process Is Limited by Transformation of Medium Molecular Weight Nitrogenous Organics but Not Hydrolysis of Proteins

Advanced Science, EarlyView.
A multi‐level analytical framework, integrating protein‐level persistence analysis, nontargeted HRMS formula tracking, peptide‐level proteomics, and targeted monomer quantification under varying redox conditions, together with FMO calculations reveal that ammonification is limited by medium molecular weight nitrogenous multimers.
Jing Li, Junjie Qiu, Fan Lü, Hua Zhang, Pinjing He   +4 more
wiley   +1 more source

PENGELOLAAN SUMBER DAYA PERIKANAN BANGGAI CARDINALFISH (PTERAPOGON KAUDERNI, KOUMANS 1933) DENGAN PENDEKATAN EKOSISTEM (STUDI KASUS PULAU BANGGAI KABUPATEN BANGGAI LAUT)

Jurnal Ilmu Pertanian Indonesia, 2016
The Banggai cardinalfish (Pterapogon kauderni) is endemic to the Banggai Archipelago. The conservation status of Pterapogon kauderni in the IUCN Red List of Threatened Species is Endangered, Pterapogon kauderni is considered to be threatened with ...
Yeldi Adel, Yonvitner, Muhammad Fadjar Rahardjo   +2 more
doaj   +1 more source