Results 111 to 120 of about 40,656 (278)

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos, Danielle Santos, Lupis Ribeiro, Jonathan J. Mucherino‐Muñoz, Marcelle Uhl, Carlos Logullo, A. Mendonça‐Amarante, M. Fantappie, Rodrigo Nunes‐da‐Fonseca   +8 more
wiley   +1 more source

Autonomous and non-autonomous differentiation of ectoderm in different sea urchin species

, 1995
During early embryogenesis, the highly regulative sea urchin embryo relies extensively on cell-cell interactions for cellular specification. Here, the role of cellular interactions in the temporal and spatial expression of markers for oral and aboral ...
Klein, W H, Wikramanayake, A H, Brandhorst, B P   +2 more
core  

The safe and effective use of tofacitinib and ustekinumab combination therapy in infantile onset inflammatory bowel disease

JPGN Reports, EarlyView.
Abstract Infantile‐onset inflammatory bowel disease (IOIBD) is a rare and severe subset of very‐early‐onset IBD, often associated with immune dysregulation and poor response to conventional therapies. Data regarding the use of Janus kinase inhibitors (JAKI) in this population is limited.
Smridhi Mahajan, Christian Wysocki, Bhaskar Gurram   +2 more
wiley   +1 more source

Neural tube-ectoderm interactions are required for trigeminal placode formation [PDF]

, 1997
Cranial sensory ganglia in vertebrates develop from the ectodermal placodes, the neural crest, or both. Although much is known about the neural crest contribution to cranial ganglia, relatively little is known about how placode cells form, invaginate and
Stark, Michael R., Marcelle, Christophe, Bronner-Fraser, Marianne, Sechrist, John   +3 more
core  

Endoscopic‐Assisted Transcervical Excision of Second Branchial Cleft Anomalies in Young Children

The Laryngoscope, EarlyView.
We describe an endoscopic‐assisted transcervical technique for excision of second branchial cleft anomalies in young children. In three cases (ages 2–8), this approach allowed safe identification and ligation of the tracts while providing improved visualization and allowing smaller incisions.
Thinh T. Kieu, Hosam H. Alkhatib, Shaunak Amin, Sheng Zhou, Kaalan Johnson   +4 more
wiley   +1 more source

mRNA and miRNA expression profiles in an ectoderm-biased substate of human pluripotent stem cells

Scientific Reports, 2019
The potential applications of human pluripotent stem cells, embryonic stem (ES) cells, and induced pluripotent stem (iPS) cells in cell therapy and regenerative medicine have been widely studied.
Shuuji Mawaribuchi, Yasuhiko Aiki, Nozomi Ikeda, Yuzuru Ito   +3 more
doaj   +1 more source

Attitudes Toward Prenatal Interventions in the Fanconi Anemia Community

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective In‐utero cell and gene therapies may offer prenatal treatment options for inherited diseases. Preclinical data suggests in‐utero (IU) hematopoietic stem cell transplantation (HSCT) could prevent Fanconi anemia (FA) related bone marrow failure without genotoxic conditioning or immune suppression.
Tony Lum, Catherine Lee, Tippi MacKenzie, Billie Lianoglou, Agnieszka Czechowicz   +4 more
wiley   +1 more source

Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Prenatal diagnostic genetic testing allows for early identification of significant fetal conditions and enables informed decision‐making regarding management options. The aim of this study was to assess prenatal testing practice among individuals with genetic conditions.
Ebunoluwa Ojo, Roni Zemet, Allyson Nevins, Katherine Abraham, April D. Adams   +4 more
wiley   +1 more source

Rohon-Beard sensory neurons are induced by BMP4 expressing non-neural ectoderm in Xenopus laevis

, 2008
Rohon-Beard mechanosensory neurons (RBs), neural crest cells, and neurogenic placodes arise at the border of the neural- and non-neural ectoderm during anamniote vertebrate development.
Kwok, Letitia, Choi, Irene F., Rossi, Christy Cortez, Klymkowsky, Michael, Hernandez-Lagunas, Laura, Zhang, Chi, Bruk Artinger, Kristin   +6 more
core   +1 more source

Mechanical plasticity of cell membranes enhances epithelial wound closure

Physical Review Research
During epithelial wound healing, cell morphology near the healed wound and the healing rate vary strongly among different developmental stages even for a single species like Drosophila.
Andrew T. Ton, Arthur K. MacKeith, Mark D. Shattuck, Corey S. O'Hern   +3 more
doaj   +1 more source