Preventing Differentiation Towards Primitive Macrophages in Stem Cells With Down Syndrome
Decreased fetal brain macrophages were previously reported in Ts1Cje mice, a model of Down syndrome (DS). We confirmed the reduction in primitive macrophages, brain macrophage precursors, using Ts1Cje‐derived mouse embryonic stem cells (Ts1Cje‐mESCs) and human induced pluripotent stem cells with trisomy 21 (Tri21‐hiPSCs), with in vivo validation ...
Koki Harada +9 more
wiley +1 more source
Generation and characterization of POMC-tdTomato reporter human pluripotent stem cell lines. [PDF]
Jovanovic VM +8 more
europepmc +1 more source
Congenital Ectodermal Defects [PDF]
openaire +2 more sources
Cell and Gene Therapy in Equine Ocular Disease
ABSTRACT Equine ocular disease is common and often challenging to treat using traditional methods. This has led to the development of new therapies. Like human medicine, veterinary medicine is adopting cellular and gene therapy as innovative approaches. Equine ocular disease is a particularly promising area for these techniques.
Kimberly A. S. Young +2 more
wiley +1 more source
The skate spiracular organ develops from a unique neurogenic placode that is distinct from lateral line placodes. [PDF]
Gillis JA +3 more
europepmc +1 more source
Mechanosensitive localization of Diversin highlights its function in vertebrate morphogenesis and planar cell polarity. [PDF]
Velayudhan SS, Chu CW, Itoh K, Sokol SY.
europepmc +1 more source
Transposable element expression and sub-cellular dynamics during hPSC differentiation to endoderm, mesoderm, and ectoderm lineages. [PDF]
Babarinde IA +13 more
europepmc +1 more source
Myocardin-related transcription factor regulates actomyosin contractility and apical junction remodeling during vertebrate neural tube closure. [PDF]
Itoh K, Ossipova O, Sokol SY.
europepmc +1 more source
Cnidaria-Inspired Morphing Mechanism for Underwater Robot: A Soft Tectonics Approach. [PDF]
Yu Y.
europepmc +1 more source
Anhydrotic Ectodermal Dysplasia [PDF]
openaire +2 more sources

