Results 81 to 90 of about 40,656 (278)

Regulation of MAP Kinase by the BMP-4/TAK1 Pathway in Xenopus Ectoderm

, 2001
Bone morphogenetic protein-4 (BMP-4) induces epidermis and represses neural fate in Xenopus ectoderm. Our previous findings implicate p42 Erk MAP kinase (MAPK) in the response to neural induction. We have examined the effects of BMP-4 on MAPK activity in
Sater, Amy K., Uzgare, Aarti R., Goswami, Mousumi   +2 more
core   +1 more source

Amniotic ectoderm expansion in mouse occurs via distinct modes and requires SMAD5-mediated signalling [PDF]

, 2018
Upon gastrulation, the mammalian conceptus transforms rapidly from a simple bilayer into a multilayered embryo enveloped by its extra-embryonic membranes. Impaired development of the amnion, the innermost membrane, causes major malformations.
Aerts, Stein, Aerts, S., Huylebroeck, D, Lawson, K.A., Stryjewska, A., Stryjewska, Agata, Sanchez, MN, Lopes, S.M.C.D., Dobreva, M.P., Pereira, P.N.G., Pereira, PNG, Paulo N. G. Pereira, Lopes, SMCDS, Escalona, V.A., Criem, N, Escalona, Vanesa Abon, Zwijsen, An, Zwijsen, A., Dobreva, MP, Sanchez, M.N., Stein Aerts, Sanchez, Marina N., Ljuba C. Ponomarev, Escalona, VA, Ponomarev, LC, Kirstie A. Lawson, Pereira, Paulo N.G., An Zwijsen, Ponomarev, Ljuba C., Marina N. Sanchez, Nathan Criem, Mariya P. Dobreva, Danny Huylebroeck, Stryjewska, A, Lawson, Kirstie A., Aerts, S, Vanesa Abon Escalona, Huylebroeck, D., Susana M. Chuva de Sousa Lopes, Dobreva, Mariya P., Huylebroeck, Danny, Criem, Nathan, Lopes, Susana M. Chuva de Sousa, Lawson, KA, Ponomarev, L.C., Criem, N., Zwijsen, A, Agata Stryjewska   +47 more
core   +1 more source

OVOL2 Maintains the Transcriptional Program of Human Corneal Epithelium by Suppressing Epithelial-to-Mesenchymal Transition

Cell Reports, 2016
In development, embryonic ectoderm differentiates into neuroectoderm and surface ectoderm using poorly understood mechanisms. Here, we show that the transcription factor OVOL2 maintains the transcriptional program of human corneal epithelium cells (CECs),
Koji Kitazawa, Takafusa Hikichi, Takahiro Nakamura, Kanae Mitsunaga, Azusa Tanaka, Masahiro Nakamura, Tatsuya Yamakawa, Shiori Furukawa, Mieko Takasaka, Naoki Goshima, Akira Watanabe, Keisuke Okita, Satoshi Kawasaki, Morio Ueno, Shigeru Kinoshita, Shinji Masui   +15 more
doaj   +1 more source

Essential embryology for the Canadian pathologists’ assistant

Anatomical Sciences Education, EarlyView.
Abstract Pathologists' assistants (PAs) are pivotal in healthcare, conducting autopsies and examining tissues under a pathologist's guidance. Embryology knowledge is crucial for PAs to accurately assess anomalies and identify pathologies. Yet, it is often overlooked in academic PA training programs.
Samantha H. Nacci, William Tsui, Fang‐I Lu, Avrum I. Gotlieb, Danielle C. Bentley   +4 more
wiley   +1 more source

Formation of neural and epidermal lineages during the differentiation of human embryonal carcinomacells [PDF]

, 2003
Within the ectoderm of the developing human embryo, cell fate determination is largely modulated by factors activated by cell-to-cell signalling. In vertebrates, ectoderm primarily differentiates into neural cells that make up the central nervous system ...
Christie, Victoria Buyers
core  

Molecular Identification of tw5: Vps52 Promotes Pluripotential Cell Differentiation through Cell–Cell Interactions

Cell Reports, 2012
After implantation, pluripotent epiblasts are converted to embryonic ectoderm through cell–cell interactions that significantly change the transcriptional and epigenetic networks.
Michihiko Sugimoto, Masayo Kondo, Michiko Hirose, Misao Suzuki, Kazuyuki Mekada, Takaya Abe, Hiroshi Kiyonari, Atsuo Ogura, Nobuo Takagi, Karen Artzt, Kuniya Abe   +10 more
doaj   +1 more source

Loss, persistence and reversal of phenotypic traits

Biological Reviews, EarlyView.
ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni, Giuseppe Fusco, Filippo Nicolini, Heather Bruce, Andrea Luchetti   +4 more
wiley   +1 more source

Repression of Inappropriate Gene Expression in the Vertebrate Embryonic Ectoderm

, 2019
During vertebrate embryogenesis, precise regulation of gene expression is crucial for proper cell fate determination. Much of what we know about vertebrate development has been gleaned from experiments performed on embryos of the amphibian Xenopus laevis;
Shoshana Reich, Daniel C. Weinstein
core   +1 more source

Ectodermal Dysplasias Revisited [PDF]

Acta geneticae medicae et gemellologiae, 1977
This paper presents a historical view of the development of the concept of ectodermal dysplasia, analyses five current “definitions” of the group, and classifies 52-57 ectodermal dysplasias into subgroups on the basis of criteria developed by the Author.
openaire   +2 more sources

Droplet microfluidics: Enabling the tailored fabrication of hydrogel particles

Droplet, EarlyView.
Droplet microfluidics enables precise, versatile fabrication of hydrogel particles with controlled size, composition, and structure. This review summarizes fundamental principles, engineering strategies, and emerging applications, providing a framework for advancing microfluidic hydrogel technologies.
Zhongqiao Gan, Xu Hou
wiley   +1 more source