Results 81 to 90 of about 2,643 (127)
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Efficient production of ectoine using ectoine-excreting strain

Extremophiles, 2009
Halophilic bacteria strain Halomonas salina DSM 5928 was found to excrete ectoine, suggesting its potential in the development of a new method of ectoine production. We performed HPLC and LC-MS analyses that showed that Halomonas salina DSM 5928 excreted ectoine under constant extracellular osmolarity.
Nagata Shinichi, Shinichi Nagata
exaly   +3 more sources

Stabilization of bovine lactoperoxidase in the presence of ectoine

Food Chemistry, 2018
Lactoperoxidase (LPO) is a heme peroxidase with various applications in industry and medicine. In this study, the effects of ectoine, as a compatible solute, on the structure, thermal stability, thermodynamic parameters, activity, and stability of LPO have been investigated.
Hashem Nayeri
exaly   +3 more sources

Design of an ectoine-responsive AraC mutant and its application in metabolic engineering of ectoine biosynthesis

Metabolic Engineering, 2015
Advanced high-throughput screening methods for small molecules may have important applications in the metabolic engineering of the biosynthetic pathways of these molecules. Ectoine is an excellent osmoprotectant that has been widely used in cosmetics. In this study, the Escherichia coli regulatory protein AraC was engineered to recognize ectoine as its
Shuang-Yan Tang   +2 more
exaly   +3 more sources

Microbial Production of Ectoine: A Review

ACS Synthetic Biology
Ectoine is an important natural secondary metabolite widely used in biomedical fields, novel cosmetics development, and the food industry. Due to the increasing market demand for ectoine, more cost-effective production methods are being explored. With the rapid development of synthetic biology and metabolic engineering technologies, the production of ...
Yi Wang, Wei Luo
exaly   +3 more sources

Ectoine hyperproduction by engineered Halomonas bluephagenesis

Metabolic Engineering
Ectoine, a crucial osmoprotectant for salt adaptation in halophiles, has gained growing interest in cosmetics and medical industries. However, its production remains challenged by stringent fermentation process in model microorganisms and low production level in its native producers.
Nigel Scrutton   +2 more
exaly   +3 more sources

Ectoine accumulation in Brevibacterium epidermis

Biotechnology Letters, 2004
As a halotolerant bacterial species, Brevibacterium epidermis DSM 20659 can grow at relatively high salinity, tolerating up to 2 M NaCl. It synthesizes ectoine and the intracellular content increases with the medium salinity, with a maximum of 0.14 g ectoine/g CDW at 1 M NaCl. Sugar-stressed cells do not synthesize ectoine.
Annelies, Onraedt   +4 more
openaire   +2 more sources

Biotechnological production of ectoine: current status and prospects

Folia Microbiologica, 2023
Ectoine is an important natural secondary metabolite in halophilic microorganisms. It protects cells against environmental stressors, such as salinity, freezing, drying, and high temperatures. Ectoine is widely used in medical, cosmetic, and other industries.
Jun Chen   +6 more
openaire   +2 more sources

Hydration in aqueous solutions of ectoine and hydroxyectoine

Physical Chemistry Chemical Physics, 2018
We explore the influence of the two osmolytes ectoine and hydroxyectoine on the structure of pure water and aqueous NaCl solutions using non-resonant X-ray Raman scattering spectroscopy at the oxygen K-edge.
Christoph J. Sahle   +3 more
openaire   +3 more sources

Supplementation effect of ectoine on thermostability of phytase

Journal of Bioscience and Bioengineering, 2006
In this study, we elucidated the supplementation effect of compatible solutes on the thermostability of phytase, designated as PHYA II, which was encoded by the phytase gene phyA I (GeneBank AY013315) from Aspergillus ficuum As3.324 and expressed in Pichia pastoris GS115.
Linghua, Zhang   +6 more
openaire   +2 more sources

Hydration and Ion Binding of the Osmolyte Ectoine

The Journal of Physical Chemistry B, 2015
Ectoine is a widespread osmolyte enabling halophilic bacteria to withstand high osmotic stress that has many potential applications ranging from cosmetics to its use as a therapeutic agent. In this contribution, combining experiment and theory, the hydration and ion-binding of this zwitterionic compound was studied to gain information on the ...
Andreas, Eiberweiser   +4 more
openaire   +2 more sources

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