Results 81 to 90 of about 5,633 (211)

Ectoine alters subcellular localization of inclusions and reduces apoptotic cell death induced by the truncated Machado–Joseph disease gene product with an expanded polyglutamine stretch

Neurobiology of Disease, 2005
Protein misfolding is considered a key event in the pathogenesis of polyglutamine disease such as Machado–Joseph disease (MJD). Overexpression of chaperone proteins and the application of chemical chaperones are reported to suppress polyglutamine induced
Kentaro Furusho, Toshihiro Yoshizawa, Shinichi Shoji   +2 more
doaj   +1 more source

Machine Learning‐based Diagnostic Potential of Bipolar Disorder Using Gut Microbiota Signatures

IET Systems Biology, Volume 20, Issue 1, January/December 2026.
Bipolar disorder (BD) has been linked to gut microbiota dysbiosis through the microbiota–gut–brain axis. Using 16S rRNA sequencing and machine learning, we found reduced microbial diversity, altered composition and identified 35 microbial biomarkers that enabled highly accurate BD diagnosis (AUC up to 0.95).
Hang Li, Yan‐Ting Jin, Dong‐Xin Ye, Qing Liu, Xi Su, Hong‐Qi Zhang, Huan Yang   +6 more
wiley   +1 more source

Transcriptomic and Ectoine Analysis of Halotolerant Nocardiopsis gilva YIM 90087T Under Salt Stress

Frontiers in Microbiology, 2018
The genus Nocardiopsis is an unique actinobacterial group that widely distributed in hypersaline environments. In this study, we investigated the growth conditions, transcriptome analysis, production and accumulation of ectoine by Nocardiopsis gilva YIM ...
Jian Han, Jian Han, Jian Han, Quan-Xiu Gao, Yong-Guang Zhang, Li Li, Osama A. A. Mohamad, Osama A. A. Mohamad, Manik Prabhu Narsing Rao, Min Xiao, Wael N. Hozzein, Wael N. Hozzein, Dalal H. M. Alkhalifah, Yong Tao, Wen-Jun Li, Wen-Jun Li   +15 more
doaj   +1 more source

Examining the Osmotic Response of Acidihalobacter aeolianus after Exposure to Salt Stress

Microorganisms, 2021
Acidihalobacter aeolianus is an acidophilic, halo-tolerant organism isolated from a marine environment near a hydrothermal vent, an ecosystem whereby levels of salinity and total dissolved salts are constantly fluctuating creating ongoing cellular ...
Melissa K. Corbett, Liam Anstiss, April Gifford, Ross M. Graham, Elizabeth L. J. Watkin   +4 more
doaj   +1 more source

Dynamics and Eco‐Genomics of Baltic Sea Nitrifiers: Seasonality, Niches, Interactions and Genomic Uniqueness

Environmental Microbiology, Volume 28, Issue 1, January 2026.
Nitrifiers in the Baltic Sea show persistent abundance in aphotic waters and late‐fall to winter photic zone increases positively correlated with nutrients and negatively with light and chlorophyll. Through selective enrichment, five novel ammonia‐oxidising archaea genomes were recovered, including the dominant aphotic taxon, which revealed overall ...
Sukki Sookyoung Kim, Elisa D'Agostino, David M. Needham   +2 more
wiley   +1 more source

Comparative functional genomics approach for the annotation of proteins in Unclassified Halophilic archaeon DL31 [PDF]

, 2012
The structure, function and sub-cellular location prediction for the unknown proteins from Unclassified Halophilic archaeon DL31 were carried out for characterization of the proteins in their respective families.
E Nakkeeran, N S. Sardeshmukh, S G. Sanmukh   +2 more
core   +1 more source

Role of central metabolism in the osmoadaptation of the halophilic bacterium chromohalobacter salexigens [PDF]

, 2013
Bacterial osmoadaptation involves the cytoplasmic accumulation of compatible solutes to counteract extracellular osmolarity. The halophilic and highly halotolerant bacterium Chromohalobacter salexigens is able to grow up to 3 M NaCl in a minimal medium ...
Argandoña Bertrán, Montserrat, Bernal, Vicente, Csonka, Laszlo N., Cánovas, Manuel, Iborra, José Luis, Nieto Gutiérrez, Joaquín José, Pastor, José M., Salvador de Lara, Manuel, Sevilla, Ángel, Vargas Macías, Carmen   +9 more
core   +1 more source

Sun Protection Advice for the South African Population for the Prevention and Management of Skin Diseases

International Journal of Dermatology, Volume 65, Issue 1, Page 57-68, January 2026.
ABSTRACT Sun protection is critical for the prevention and management of skin cancer and other photosensitive dermatoses in South Africa's diverse population. This review expands on previously published sun protection advice for skin cancer prevention by providing tailored advice for individuals with specific dermatological conditions.
Thuraya Isaacs, Tarryn Jacobs, Dagmar Whitaker, Willem Visser, Kim Wiid, Ncoza C. Dlova, Caradee Y. Wright, Bianca Tod   +7 more
wiley   +1 more source

The Diverse Roles of the Histone‐Like Nucleoid Structuring (H‐NS) Protein in Vibrio parahaemolyticus

Genetics Research , Volume 2026, Issue 1, 2026.
The histone‐like nucleoid structuring (H‐NS) protein is a global transcriptional regulator critical for bacterial genome organization and gene expression. In Vibrio parahaemolyticus, H‐NS represses virulence factors such as thermostable direct hemolysin (TDH), type III secretion systems (T3SS1/T3SS2), and type VI secretion systems (T6SS1/T6SS2).
Hao Tang, Yiquan Zhang, Richa Sharma
wiley   +1 more source

Osmotic stress confers enhanced cell integrity to hydrostatic pressure but impairs growth in Alcanivorax borkumensis SK2 [PDF]

, 2016
Alcanivorax is a hydrocarbonoclastic genus dominating oil spills worldwide. While its presence has been detected in oil-polluted seawaters, marine sediment and salt marshes under ambient pressure, its presence in deep-sea oil-contaminated environments is
Boon, Nico, Scoma, Alberto
core   +3 more sources