Results 1 to 10 of about 720 (130)

Hao1 Is Not a Pathogenic Factor for Ectopic Ossifications but Functions to Regulate the TCA Cycle In Vivo [PDF]

open access: yesMetabolites, 2022
Ossification of the posterior longitudinal ligament (OPLL), a disease characterized by the ectopic ossification of a spinal ligament, promotes neurological disorders associated with spinal canal stenosis.
Atsushi Kimura   +18 more
doaj   +4 more sources

Neurogenic Heterotopic Ossifications Recapitulate Hematopoietic Stem Cell Niche Development Within an Adult Osteogenic Muscle Environment

open access: yesFrontiers in Cell and Developmental Biology, 2021
Hematopoiesis and bone interact in various developmental and pathological processes. Neurogenic heterotopic ossifications (NHO) are the formation of ectopic hematopoietic bones in peri-articular muscles that develop following severe lesions of the ...
Dorothée Girard   +11 more
doaj   +3 more sources

Histomorphological changes in autologous anterior cruciate ligament graft failure show predominantly inflammatory reactions, fissure defects and osteonecrosis [PDF]

open access: yesJournal of Experimental Orthopaedics
Purpose The aim of this study was to identify morphological alterations that occur in graft failure following anterior cruciate ligament (ACL) reconstruction. It was hypothesised that multiple morphological regression phenomena are present at the time of
Steffen F. Siemoneit   +6 more
doaj   +2 more sources

Fibrodysplasia ossificans progressiva associated with osteochondromatosis: A case report [PDF]

open access: yesRadiology Case Reports
Fibrodysplasia ossificans progressiva is a rare and severely debilitating genetic disorder affecting approximately 1 in 2 million people. It is characterized by progressive heterotopic ossification of soft tissues, leading to the formation of ectopic ...
Jihane El Houssni   +6 more
doaj   +2 more sources

Prevalence of hearing loss in pseudohypoparathyroidism [PDF]

open access: yesOrphanet Journal of Rare Diseases
Background The main clinical features of pseudohypoparathyroidism (PHP)/inactivating parathyroid hormone/parathyroid hormone-related protein signaling disorders (iPPSD), including parathyroid hormone (PTH) resistance, brachydactyly and short stature ...
Cassandre Djian   +5 more
doaj   +2 more sources

Pseudohypoparathyroidism and its various phenotypes: three sisters with three different clinical presentations

open access: yesAtti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche, 2021
Pseudohypoparathyroidism (PHP) is a heterogeneous group of hereditary disorders characterized by clinical and biological characteristics of resistance to parathyroid hormone (PTH) caused by impaired hormonal signalling via receptors that are coupled ...
Fabio Sippelli   +5 more
doaj   +1 more source

Familial ectopic ossification. [PDF]

open access: yesJournal of Medical Genetics, 1988
We report a family with dominantly inherited ectopic ossification. It is characterised by childhood onset of multifocal subcutaneous ossifications (primary osteoma cutis), which are of trivial clinical significance. One family member had extensive ectopic ossification involving one limb. We speculate that this may reflect somatic mutation having caused
R J, Gardner, K, Yun, S M, Craw
openaire   +2 more sources

Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles

open access: yesBone Research, 2022
The cells of origin of neurogenic heterotopic ossifications (NHOs), which develop frequently in the periarticular muscles following spinal cord injuries (SCIs) and traumatic brain injuries, remain unclear because skeletal muscle harbors two progenitor ...
Hsu-Wen Tseng   +17 more
doaj   +1 more source

The Teratogenic Effects of Glyphosate Based Herbicide (GBH) on the Development of Chick Embryos

open access: yesSiriraj Medical Journal, 2018
Objective: This study was conducted to investigate the teratogenic effects of GBH by using chick embryo as an animal model. Methods: The equal volume of 0.1 ml of 0.01%, 0.05%, 0.3%, and 0.5% w/v glyphosate solution were injected into yolk sacs of ...
Jantima Roongruangchai, D.D.S., Ph.D.   +5 more
doaj   +3 more sources

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