Results 21 to 30 of about 15,580 (252)

Identifying the Most Relevant Eczema Area and Severity Index Thresholds from the Patient Perspective in Atopic Dermatitis Treatment. [PDF]

Am J Clin Dermatol
Atopic dermatitis (AD) is a chronic inflammatory disease significantly impacting patients' quality of life (QoL). While multiple outcome measures exist, a critical gap remains in establishing treatment goals that meaningfully connect improvements in clinician-reported outcome measures (ClinROMs) with patient-reported outcome measures (PROMs).To ...
Eichenfield LF, Lio PA, Irvine AD, Apfelbacher CJ, Kabashima K, Praestgaard AH, Wang Z, Bastian M.   +7 more
europepmc   +3 more sources

Standardized reporting of the Eczema Area and Severity Index (EASI) and the Patient-Oriented Eczema Measure (POEM): a recommendation by the Harmonising Outcome Measures for Eczema (HOME) Initiative [PDF]

British Journal of Dermatology, 2018
Several organizations from multiple fields of medicine are setting standards for clinical research including protocol development,1 harmonization of outcome reporting,2 statistical analysis,3 quality assessment4 and reporting of findings.1 Clinical research standardization facilitates the interpretation and synthesis of data, increases the usability of
E.E. Grinich, J. Schmitt, D. Küster, P.I. Spuls, H.C. Williams, J.R. Chalmers, K.S. Thomas, C. Apfelbacher, C.A.C. Prinsen, M. Furue, B. Stuart, B. Carter, E.L. Simpson   +12 more
openaire   +3 more sources

Clinically meaningful improvements in cutaneous lesions and quality of life measures in patients with atopic dermatitis with greater pruritus reductions after treatment with 60 mg nemolizumab subcutaneously every 4 weeks: subgroup analysis from a phase 3, randomized, controlled trial

Journal of Dermatological Treatment, 2023
Background Data from the Japanese phase 3 Nemolizumab-JP01 study (JapicCTI-173740) found that nemolizumab in combination with topical treatments reduced pruritus associated with atopic dermatitis inadequately controlled with current therapies.
Kenji Kabashima, Takayo Matsumura, Yoshiteru Hayakawa, Makoto Kawashima, for the Nemolizumab-JP01 Study Group   +4 more
doaj   +1 more source

Correlation of Contact Sensitization to Common Allergens with Disease Severity in Discoid Eczema: An Analytical Observational Study

Clinical Dermatology Review, 2022
Background: Discoid eczema, defined by well-demarcated round or oval plaques, is a form of endogenous eczema in which the role of contact allergens is not clearly established. Objectives: This study aims to assess the role of contact allergens in discoid
Aishwarya Raheja, Ajay Kumar, Avinash Jadhav, Mahendra Singh Deora, Dipti Mathias, Prachi Agrawal, Rahul Ranpariya   +6 more
doaj   +1 more source

Eczema

, 2011
As defined by the World Allergy Organization (WAO) revised nomenclature in 2003, eczema (also known as atopic dermatitis)[1] is a chronic, relapsing, and itchy inflammatory skin condition.
Schmitt, Jochen, Apfelbacher, Christian J, Flohr, Carsten; id_orcid   +2 more
core   +4 more sources

Efficacy and safety of a skin healing cream in mild-to-moderate eczema in a mixed population including infants: An open-label, single-arm study

Indian Journal of Paediatric Dermatology, 2023
Introduction: Atopic dermatitis is an inflammatory skin condition that begins in infancy, characterized by extreme skin dryness, excoriations, and erythema.
Shilpa Dhar, Trupti Patel, Arohi Bapna, Govindarajan Raghavan   +3 more
doaj   +1 more source

Responsiveness and interpretability of the Hand Eczema Severity Index (HECSI) [PDF]

, 2020
Background: The Hand Eczema Severity Index (HECSI) is used to measure the severity of hand eczema. It is unclear what HECSI scores mean and what is the minimally important change (MIC). Furthermore, its responsiveness has not been studied. Objectives: To
Oosterhaven, J A F; id_orcid, Schuttelaar, M L A; id_orcid   +1 more
core   +1 more source

Efficacy of Dupilumab for Atopic Dermatitis According to Clinical Course and Clinical Findings: A Multicentre Retrospective Study

Acta Dermato-Venereologica, 2021
is missing (Short communication)
Takeshi Nakahara, Makiko Kido-Nakahara, Daisuke Onozuka, Sawako Sakai, Tomoko Hirose, Nobutoshi Take , Akiko Sugiyama, Kayo Harada, Gaku Tsuji, Satoko Kikuchi, Futoshi Kohda   +10 more
doaj   +1 more source

Model-Based Meta-Analysis to Optimize Staphylococcus aureus‒Targeted Therapies for Atopic Dermatitis

JID Innovations, 2022
Several clinical trials of Staphylococcus aureus (S. aureus)‒targeted therapies for atopic dermatitis (AD) have shown conflicting results about whether they improve AD severity scores.
Takuya Miyano, Alan D. Irvine, Reiko J. Tanaka   +2 more
doaj   +1 more source

Atopic Dermatitis in Children in the General Population:Baseline Characteristics, Medication Use, and Severity Measures in the Rotterdam Eczema Study [PDF]

, 2023
Background : Real-life data on severity and treatments in children with atopic dermatitis (AD) are needed to evaluate self-management. Objectives : To determine severity and use of topical treatments in children with AD in the general population ...
Gijs Elshout, Karlijn F. van Halewijn, Elshout, Gijs, van der Most, Floor, Patrick J.E. Bindels, van Halewijn, Karlijn F.; id_orcid, Bindels, Patrick J.E.; id_orcid, Pasmans, Suzanne G.M.A., Suzanne G.M.A. Pasmans, Arthur M. Bohnen, Floor van der Most, Bohnen, Arthur M.   +11 more
core   +1 more source