Results 151 to 160 of about 492,962 (322)

A severity‐based tumor‐superior mesenteric/portal vein interface grading criteria as a predictor of survival outcomes in pancreatic head ductal adenocarcinoma patients undergoing pancreaticoduodenectomy following neoadjuvant chemoradiotherapy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
PDAC patients with the radiological severe interface (≥25 contact length and ≥210 degrees circumferential tumor‐SMV/PV interface) may help predict poor survival outcomes preoperatively. Abstract Aim To assess the ability of a new severity‐based tumor‐superior mesenteric/portal vein interface criteria to predict survival outcomes in pancreatic ductal ...
Benson Kaluba   +9 more
wiley   +1 more source

Multifunctional Biomimetic Nanotherapeutics for Anti‐Oxidative and Anti‐Inflammatory Synergistic Therapy of Corneal Neovascularization

open access: yesAggregate, EarlyView.
An anti‐inflammatory and antioxidant metal‐organic framework (MOF) nanoplatform was prepared via one‐pot self‐assembly. In vitro and in vivo studies demonstrated that the prepared MVPC nanoparticles can effectively scavenge overproduced reactive oxygen species at diseased sites, enhance IL‐10 secretion, and suppress VEGFA expression, offering a novel ...
Shundong Cai   +12 more
wiley   +1 more source

Extracellular Matrix Targeted MRI Probes

open access: yesAnalysis &Sensing, Volume 3, Issue 1, January 2023., 2023
Gadolinium based MRI probes targeted to ECM components, either proteins or enzymes, hold promise for accurate molecular characterization and staging of fibrotic diseases in vivo. Non‐covalent binding probes (1), reactive probes (2), and enzyme‐responsive probes (3) are discussed.
Giuseppe Digilio   +3 more
wiley   +1 more source

Enhanced Synergistic Photothermal–Chemotherapy in Bacterial Keratitis Treatment Using Halogen‐Bonded Organic Frameworks (XOFs) Based on N⋯Br+⋯N Bonds

open access: yesAggregate, EarlyView.
Two novel XOFs based on [N···Br+···N] interactions were constructed. The XOFs(Br) deliver superior antibacterial properties compared with XOFs(I), due to a greater oxidation capability. Moreover, XOF(Br)‐TPPA, exhibiting greater hydrophilicity, shows superior antibacterial properties relative to XOF(Br)‐TPPE, which is weakly hydrophilic.
Zhennan Tian   +13 more
wiley   +1 more source

Mesenteric thrombosis: An unusual complication of severe acute pancreatitis—Report of two cases

open access: yesAdvances in Digestive Medicine, EarlyView.
Abstract The incidence of acute pancreatitis is 34 per 100 000 people in the general population and is on the rise. Approximately 15% to 20% of all patients experience severe pancreatitis, with a mortality rate nearing 20%. This condition is often linked to vascular complications, although mesenteric thrombosis is a rare presentation.
Asya Zubillaga‐Mares   +5 more
wiley   +1 more source

Deep Learning-Based Detection of Referable Diabetic Retinopathy and Macular Edema Using Ultra-Widefield Fundus Imaging [PDF]

open access: yesarXiv
Diabetic retinopathy and diabetic macular edema are significant complications of diabetes that can lead to vision loss. Early detection through ultra-widefield fundus imaging enhances patient outcomes but presents challenges in image quality and analysis scale.
arxiv  

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