Results 181 to 190 of about 914,385 (293)

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Corrigendum: Chronic systemic capillary leak syndrome with lymphatic capillaries involvement and MYOF mutation: case report and literature review

Frontiers in Genetics
Dehua Gao, Wen Zhong, Weiru Zhang, Xuan Wang, Weiping Li, Jun Liu   +5 more
doaj   +1 more source

Identification and management of Descemet's membrane detachment during glaucoma and cataract surgery. [PDF]

Int J Ophthalmol
Al Habash A, Alkhoutani E, Bin Helayel H.   +2 more
europepmc   +1 more source

Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound

Advanced Science, EarlyView.
Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García, José A. Pineda‐Pardo, Inés Trigo‐Damas, Marta Gutiérrez, Marta Castillo‐Ortiz, Megan Carrillo, Alejandro Reinares‐Sebastian, Víctor Medina‐Chavarrías, Itay Rachmilevitch, Masahiko Takada, José A. Obeso, Javier Blesa   +11 more
wiley   +1 more source

Cytotoxic Edema and Intra-parenchymal Hemorrhage: A Mediated Pathway to Mortality and Functional Outcome in Cerebral Venous Sinus Thrombosis- A sub-analysis of the CLOT-VENUS Registry. [PDF]

Transl Stroke Res
Abdelhakim N, Galecio-Castillo M, Kalakoti P, Cruz-Criollo L, Rodriguez-Calienes A, Brito A, Cespedes J, Shaban A, Venkatesan A, Nigenda VC, Pompa AAM, Mohr NM, Pereda-Castillo A, Peregrino KE, Ruvalcaba HV, Smith BJ, Torner JC, Barboza MA, Arauz A, Ortega-Gutierrez S.   +19 more
europepmc   +1 more source

A Biomimetic Nanoparticle System Intercepts and Degrades Thrombospondin‐1 to Restore Vascular Homeostasis After Ischemic Injury

Advanced Science, EarlyView.
TAX2‐NPs capture extracellular TSP‐1 in the injured liver and promote its macrophage‐mediated autophagic degradation. This process blocks TSP‐1/CD47 signaling, restores VEGFR2‐AKT activity, preserves endothelial function, and mitigates hepatic ischemia‐reperfusion injury.
Haorui Wang, Xiandi Meng, Yanbao Xin, Kuirong Mao, Huizhu Tan, Changkai Ma, Xiuxiu Cong, Mengfei Zhao, Meiling Yu, Si Chen, Yue Hou, Yong‐Guang Yang, Tianmeng Sun   +12 more
wiley   +1 more source

Acute pulmonary Edema following Myometrial pituitrin injection during laparoscopic myomectomy. [PDF]

Oxf Med Case Reports
Wang Z, Song S, Zhang J.
europepmc   +1 more source

Interface Wettability Transition‐Driven Drug Release and Dual‐Phase Functionalization in Implant Abutment

Advanced Science, EarlyView.
A temporally controlled drug release coating is developed for abutments using a superhydrophobic coating self‐assembled on mesoporous silica. This surface provides sequential functionality: initial contamination resistance through non‐wetting, followed by controlled drug release via wettability transition.
Zhongchao Wang, Liang Shi, MingXia Li, Xiao Han, Jinghan Wang, Guangping Wang, Dan Zou, Bingyang Lu, Liyuan Fan   +8 more
wiley   +1 more source

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

Advanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang, Yanling Gou, Huiyan Zhang, Hongli Wang, Beidi Wang, Jinming Liu, Yingying Cao, Ruru Bai, Yuxin Zhao, Xu Han, Chao Feng, Xin Huang, Zongfeng Zhang   +12 more
wiley   +1 more source

Severe edema as an immune-related adverse event following nivolumab therapy: a case report. [PDF]

AME Case Rep
Miyamoto N, Tsuji A, Matsui S, Takehara E, Takeuchi T, Fujimoto K, Morishita A, Kawakita N, Toba H, Takizawa H.   +9 more
europepmc   +1 more source