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Edetic Acid Therapy

JAMA: The Journal of the American Medical Association, 1970
To the Editor.— The Food and Drug Administration has recently stated that unless further information is made available regarding the efficacy of the oral form of edetate calcium disodium (EDTA) that after six months, this form will be removed from the market.
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Spectrophotometric Titration of Edetic Acid in Ophthalmic Solutions

Journal of Pharmaceutical Sciences, 1974
The procedure described here is applicable for determining edetic acid (ethylenediaminetetraacetic acid) at the 0.05–0.2% level in ophthalmic solutions. This method employs a spectrophotometric titration, using a magnesium-ion solution as titrant and arsenazo I as the indicator.
E E, Kaminski, D M, Pacenti
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