Results 111 to 120 of about 90,240,046 (296)

Predictive Utility of EROA/LVEDV Ratio in Mitraclip Outcomes: Retrospective Multicenter Cohort Study

Medicina
Background: The effective regurgitant orifice area to left ventricular end-diastolic volume (EROA/LVEDV) ratio has been proposed to distinguish proportionate from disproportionate functional mitral regurgitation and to guide patient selection for ...
Vivek Joseph Varughese, Chandler Richardson, James Pollock, Patryk Czyzewski, Ashley Lyons, Hata Mujadzic, Deborah M. Hurley, Michael Cryer, Sunil V. Rao, Akshay Kumar   +9 more
doaj   +1 more source

Atrial Functional Mitral Regurgitation Subtypes Undergoing Transcatheter Edge-to-Edge Repair: Suboptimal Outcomes in Atriogenic Hamstringing.

JACC Cardiovascular Imaging
BACKGROUND Two subtypes of atrial functional mitral regurgitation (AFMR) have been described, one is characterized by Carpentier type I and the other by Carpentier type IIIb leaflet motion.
Philipp von Stein, Jennifer von Stein, Christopher Hohmann, H. Wienemann, Henning Guthoff, M. I. Körber, Stephan Baldus, Roman Pfister, Rebecca T. Hahn, C. Iliadis   +9 more
semanticscholar   +1 more source

Map of property of Kline Realty & Improvement Co.

, 1910
Property map showing planned subdivision called River Edge ...

core  

Relation of Residual Mitral Regurgitation and Gradient Following Mitral Valve Transcatheter Edge-to-Edge Repair

Mustafa D, von Stein J, Stolz L, et al. Relation of Residual Mitral Regurgitation and Gradient Following Mitral Valve Transcatheter Edge-to-Edge Repair. Circulation: Cardiovascular Interventions .
Schindhelm, Florian, Guthoff, Henning, Mues, Christoph Alexander, Granada, Juan F., Ascione, Guido, Rassaf, Tienush, Unsöld, Bernhard, Jobst, Jannik, Schofer, Niklas, Stolz, Lukas, Hausleiter, Jörg, Sagmeister, Paula, Gerçek, Muhammed, Möllmann, Helge, Gröger, Matthias, Rudolph, Volker, Kister, Tobias, Schulz, Carl, Rottbauer, Wolfgang, Mauri, Victor, Pfister, Roman, Mustafa, Donika, Konstandin, Mathias H., Sugiura, Atsushi, Weber, Marcel, Rudolph, Felix, Hoerbrand, Isabel A., Wolff, Charlotte, Horn, Patrick, Baldus, Stephan, Kessler, Mirjam, von Stein, Jennifer, Lurz, Philipp, Mahabadi, Amir Abbas, Haurand, Jean Marc, von Stein, Philipp   +35 more
core   +1 more source

Transaxillary Mitral Valve Repair After Failed Percutaneous Edge-to-Edge Repair

, 2022
As the execution of percutaneous edge-to-edge repair increases, so does the need for surgical treatment of failed procedures. Mitral valve surgery after failed percutaneous edge-to-edge repair can be complex and the feasibility of surgical mitral valve ...
Eugenio Alessandroni (11914785), Mariano Cefarelli (5533910), Marco Di Eusanio (7027669)   +2 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Multicenter Evaluation of an Edge-to-Edge Repair System in High-Risk Patients With Degenerative Mitral Regurgitation

Structural Heart
Background: Transcatheter edge-to-edge repair (TEER) has become an effective alternative for treating degenerative mitral regurgitation (DMR) in patients at high surgical risk.
Kai Xu, MD, PhD, Junjie Zhang, MD, PhD, Da Zhu, MD, PhD, Yan Wang, MD, PhD, Hong Jiang, MD, PhD, Jing Chen, MD, PhD, Jiyan Chen, MD, PhD, Jiancheng Xiu, MD, PhD, Ben He, MD, PhD, RuiYan Zhang, MD, PhD, Xiaogang Guo, MD, PhD, ChuanYu Gao, MD, PhD, ZhiXiong Zhong, MD, Ping Li, MS, DaJun Chai, MD, PhD, Jun Jin, MD, Yuguo Chen, MD, PhD, Lang Hong, MS, Yida Tang, MD, Guosheng Fu, MD, PhD, Ling Tao, MD, PhD, Yining Yang, MD, PhD, Shenghua Zhou, MD, PhD, Bin Liu, MD, PhD, Lijun Gan, MD, Bo Yu, MD, PhD, Maurizio Taramasso, MD, PhD, Xiangbin Pan, MD, PhD, Shaoliang Chen, MD, PhD, Yaling Han, MD, PhD   +29 more
doaj   +1 more source

Mitral Valve Transcatheter Edge-to-Edge Repair: 1-Year Outcomes From the MiCLASP Study.

JACC: Cardiovascular Interventions
BACKGROUND Mitral transcatheter edge-to-edge repair (M-TEER) is a guideline-recommended treatment option for patients with severe symptomatic mitral regurgitation (MR). Outcomes with the PASCAL system in a post-market setting have not been established.
P. Lurz, Thomas Schmitz, Tobias Geisler, J. Hausleiter, I. Eitel, V. Rudolph, E. Lubos, R. von Bardeleben, N. Brambilla, F. de Marco, S. Berti, H. Nef, Axel Linke, C. Hengstenberg, S. Baldus, K. Spargias, P. Denti, G. Nickenig, H. Möllmann, W. Rottbauer, F. Praz, C. Butter, M. Reinthaler, N. M. Van Mieghem, Mohammad Sherif, M. Swaans, A. Witkowski, Mamta Buch, Tim Seidler, Andrés Iñiguez, H. Thiele, M. Eißmann, Juergen Schreieck, M. Nabauer, L. Marcoff, K. Koulogiannis, T. Rassaf, P. Luedike   +37 more
semanticscholar   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source