Results 61 to 70 of about 90,240,046 (296)

«Edge-to-edge» mitral valve repair for septal myectomy versus isolated myectomy: a pilot randomized trial

, 2023
Background. Septal myectomy  is currently the «gold» standard of surgical treatment  of patients with obstructive  hypertrophic  cardiomyopathy.  In some  cases,  isolated septal myectomy does  not eliminate SAM-induced mitral insufficiency.
S. I. Zheleznev, S. A. Budagaev, A. M. Chernyavsky, A. S. Zalesov, A. V. Afanasyev, R. M. Sharifulin, A. V. Bogachev-Prokophiev, D. Y. Kozmin   +7 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Single-center experience with percutaneous mitral valve repair using the MitraClip in a high-risk series in Turkey

Türk Kardiyoloji Derneği Arşivi, 2016
Objective: Mitral valve regurgitation (MR) is the second most common heart valve disease in Europe. Without intervention, prognosis of severe symptomatic MR is poor.
Cüneyt Toprak, Gökhan Kahveci, Alev Kılıcgedik, Cevat Kırma, Selcuk Pala, Mustafa Bulut, Cihangir Kaymaz, Nihal Ozdemir, İbrahim Akın İzgi, Mehmet Inanır, Anıl Avcı, Ali Metin Esen   +11 more
doaj   +1 more source

Characteristics and outcomes of patients with atrial versus ventricular secondary tricuspid regurgitation undergoing tricuspid transcatheter edge‐to‐edge repair – Results from the TriValve registry

European Journal of Heart Failure, 2023
Functional or secondary tricuspid regurgitation (STR) is the most common phenotype of tricuspid regurgitation (TR) with atrial STR (ASTR) and ventricular STR (VSTR) being recently identified as two distinct entities.
G. Russo, L. Badano, M. Adamo, H. Alessandrini, M. Andreas, Daniel Braun, Kim A. Connelly, P. Denti, R. Estévez-Loureiro, N. Fam, M. Gavazzoni, Rebecca T. Hahn, C. Harr, J. Hausleiter, D. Himbert, D. Kalbacher, E. Ho, Azeem Latib, Edith Lubos, Sebastian Ludwig, P. Lurz, V. Monivas, G. Nickenig, D. Pedicino, G. Pedrazzini, A. Pozzoli, Denise Pires Marafon, R. Pastorino, F. Praz, J. Rodés-Cabau, C. Besler, Joachim Schofer, A. Scotti, K. Piayda, H. Sievert, Gilbert H. L. Tang, H. Thiele, F. Schlotter, Ralph-Stephan von Bardeleben, J. Webb, Stephan Windecker, M. Leon, Francesco Maisano, M. Metra, M. Taramasso   +44 more
semanticscholar   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Transcatheter Edge-to-Edge Repair in Patients With Primary Tricuspid Regurgitation.

JACC: Cardiovascular Interventions
BACKGROUND Tricuspid regurgitation (TR) leads to right heart congestion and increased mortality risk. Unlike secondary TR, primary TR results from leaflet degeneration. Transcatheter edge-to-edge repair (TEER) is widely used for TR.
A. Sugiura, J. Dreyfus, S. Bombace, M. Ivannikova, J. Bartkowiak, Stephan Haussig, L. Schneider, M. Kassar, Patrick Horn, M. Taramasso, C. Iliadis, Itsuki Osawa, Tadahiro Goto, M. Weber, Tetsu Tanaka, Sebastian Zimmer, J. Obadia, G. Habib, B. Bazire, B. Iung, Y. Bohbot, Christophe Tribouilloy, E. Donal, M. Nejjari, E. Riant, T. Letourneau, Y. Lavie-Badie, A. Coisne, T. Modine, Pascal Lim, F. Doguet, C. Selton-Suty, S. Baldus, M. Kelm, F. Praz, W. Rottbauer, Axel Hans-Peter Linke, Rebecca T. Hahn, Rudolph Volker, D. Messika-Zeitoun, P. Lurz, G. Nickenig   +41 more
semanticscholar   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Percutaneous Edge-to-Edge Repair for Tricuspid Regurgitation: 3-Year Outcomes From the TRILUMINATE Study.

JACC: Cardiovascular Interventions
BACKGROUND Tricuspid regurgitation (TR) is a common valve disease that has a significant impact on patients' quality of life. OBJECTIVES This study sought to report the final 3-year outcomes of tricuspid transcatheter edge-to-edge repair (T-TEER) with ...
G. Nickenig, P. Lurz, P. Sorajja, Ralph-Stephan von Bardeleben, M. Sitges, Gilbert H. L. Tang, J. Hausleiter, J. Trochu, M. Nabauer, Megan Heitkemper, Shih-Wa Ying, M. Weber, Rebecca T. Hahn   +12 more
semanticscholar   +1 more source

Short-Term Outcomes Following Transcatheter Edge-to-Edge Repair

JACC: Asia, 2023
Background Transcatheter edge-to-edge repair (TEER) is a less invasive treatment for patients with mitral regurgitation (MR). Limited safety and efficacy data of TEER with MitraClip, including the fourth-generation (G4) system, in a large cohort, are ...
M. Saji, M. Yamamoto, S. Kubo, M. Asami, Y. Enta, S. Shirai, Izumo Masaki, S. Mizuno, Y. Watanabe, M. Amaki, Kazuhisa Kodama, Junichi Yamaguchi, Y. Nakajima, T. Naganuma, H. Bota, Y. Ohno, M. Yamawaki, H. Ueno, K. Mizutani, Y. Adachi, T. Otsuka, K. Hayashida   +21 more
semanticscholar   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source