Results 81 to 90 of about 90,240,046 (296)

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Streamlining postprocedural care after transcatheter edge-to-edge repair

BMC Cardiovascular Disorders
Background Patients undergoing transcatheter edge-to-edge repair (TEER) of the mitral or tricuspid valve are predominantly elderly and exhibit high rates of frailty.
Jakob Christoph Voran, Jan Baucks, Violetta Catania, Peter Bramlage, Derk Frank, Felix Kreidel   +5 more
doaj   +1 more source

Edge-to-edge transcatheter tricuspid repair for isolated posterior prolapse

REC: Interventional Cardiology (English Ed.)
The adoption of transcatheter tricuspid valve repair (TTVR) with the edge-to-edge technique has rapidly grown. Functional tricuspid regurgitation (TR) is the most common indication, and the most common approaches are to grasp either the septal and ...
José Luis Betanzos, Alberto Alperi, Víctor León, Iria Silva, Pablo Avanzas, Isaac Pascual   +5 more
doaj   +1 more source

[Long-term clinical and echocardiographic follow-up of the edge-to-edge technique for surgical mitral valve repair]

, 2020
To evaluate the long-term clinical and echocardiographic performance of mitral valve repair with the edge-to-edge ...
Rubino, Antonino S, Mignosa, Carmelo, Gentile, Maurizio, Cavallaro, Alfio, Di Bartolo, Massimo, Castorina, Sergio, Patanè, Leonardo, Patane L., Mignosa C., Rubino A. S., Di Bartolo M., Cavallaro A., Castorina S., Gentile M.   +13 more
core   +1 more source

Intraoperative Evaluation of Transmitral Pressure Gradients after Edge-to-Edge Mitral Valve Repair [PDF]

, 2014
Objective: Edge-to-edge repair of the mitral valve (MV) has been described as a viable option used for the surgical management of mitral regurgitation (MR).
Eltzschig, Holger K., Shernan, Stanton, Hilberath, Jan N., Worthington, Andrea H., Nowak-Machen, Martina, Aranki, Sary   +5 more
core   +1 more source

Edge-connected pixel task.

, 2022
(A) Illustration of the general connectivity task and its global nature. (B) Example of an input image and correct labelling for that image in the edge-connected pixel task. (C) Implementation of the single-hidden layer architecture for detecting whether
Brett W. Larsen (12902597), Shaul Druckmann (208894)   +1 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Long-Term Outcomes After Edge-to-Edge Repair of Secondary Mitral Regurgitation: 5-Year Results From the EuroSMR Registry.

JACC: Cardiovascular Interventions
BACKGROUND Mitral valve transcatheter edge-to-edge repair (M-TEER) reduces secondary mitral regurgitation (MR) in heart failure and impacts survival in selected patients as demonstrated in the COAPT (Cardiovascular Outcomes Assessment of the MitraClip ...
T. Stocker, L. Stolz, N. Karam, D. Kalbacher, Benedikt Koell, T. Trenkwalder, E. Xhepa, M. Adamo, M. Spieker, P. Horn, C. Butter, L. Weckbach, Julia Novotny, Bruno Melica, C. Giannini, R. von Bardeleben, R. Pfister, F. Praz, P. Lurz, V. Rudolph, M. Metra, J. Hausleiter   +21 more
semanticscholar   +1 more source

Edge-to-Edge Oriented Self-Assembly of ReS₂ Nanoflakes

, 2016
The self-assembly of two-dimensional (2D) nanomaterials, an emerging research area, still remains largely unexplored. The strong interlayer attraction between 2D nanosheets leads to face-to-face stacking rather than edge-to-edge coupling. We demonstrate,
Shengli Chen (1724470), Rafael G. Mendes (1453654), Liwen Fang (2880515), Lei Fu (429363), Xin Kong (3074835), Qin Zhang (58638), Yao Xiao (227567), Mark H. Rümmeli (1300254), Yinghui Xue (1699417), Wenjie Wang (413433)   +9 more
core   +1 more source

Predictors of optimal procedural result after transcatheter edge-to-edge mitral valve repair in secondary mitral regurgitation

, 2022
Background: Procedural success after transcatheter edge-to-edge mitral valve repair (TEER) is defined as a reduction of mitral regurgitation (MR) degree ...
Mongiardo A., Tusa M., Popolo Rubbio A., Metra M., Villa E., Godino C., Tamburino C., Monteforte I., Bedogni F., Grasso C., Denti P., De Marco F., Giannini C., Bartorelli A. L., Adamo M., Tarantini G., Testa L., Pagnesi M., Citro R., Lupi L., Curello S., Branca L., Giordano A., De Felice F., Carmelo Grasso, Federico De Marco, Giordano, Arturo, Rodolfo Citro, Marianna Adamo, Paolo Denti, Arturo Giordano, Antonio L. Bartorelli, Francesco De Felice, Luca Testa, Branca, Luca, Annalisa Mongiardo, De Marco, Federico, Matteo Pagnesi, Curello, Salvatore, Emmanuel Villa, Giuseppe Tarantini, Laura Lupi, Tusa, Maurizio, Mongiardo, Annalisa, Grasso, Carmelo, Bedogni, Francesco, Luca Branca, Francesco Bedogni, Tarantini, Giuseppe, Citro, Rodolfo, Denti, Paolo, Metra, Marco, Ida Monteforte, Pagnesi, Matteo, Giannini, Cristina, Cristina Giannini, Lupi, Laura, Villa, Emmanuel, Tamburino, Corrado, De Felice, Francesco, Citro, R, Antonio Popolo Rubbio, Cosmo Godino, Popolo Rubbio, Antonio, Godino, Cosmo, Testa, Luca, Salvatore Curello, Bartorelli, Antonio L, Maurizio Tusa, Adamo, Marianna, Marco Metra, Corrado Tamburino, Monteforte, Ida   +72 more
core   +1 more source