Results 31 to 40 of about 2,114,184 (246)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Exploring Computing Paradigms for Electric Vehicles: From Cloud to Edge Intelligence, Challenges and Future Directions

open access: yesWorld Electric Vehicle Journal
Electric vehicles are widely adopted globally as a sustainable mode of transportation. With the increased availability of onboard computation and communication capabilities, vehicles are moving towards automated driving and intelligent transportation ...
Sachin B. Chougule   +3 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Traffic Accident Severity Classification Using ResNet-18 [PDF]

open access: yesE3S Web of Conferences
The paper describes a system of automated classification of the severity of traffic accidents based on a fine-tuned ResNet-18 architecture. To meet the requirement of quick emergency reaction in low-resource urban areas, we pre-selected a dataset of ...
Oluwadamilola Oni, Emmanuel Ogbonnia
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Roadmap for Edge AI: A Dagstuhl perspective [PDF]

open access: yes, 2022
Based on the collective input of Dagstuhl Seminar (21342), this paper presents a comprehensive discussion on AI methods and capabilities in the context of edge computing, referred as Edge AI.
Dustdar, Schahram (author)   +61 more
core   +2 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Optimizing air handling unit operations in clean rooms using artificial intelligence

open access: yesJournal of Thermal Engineering
Cleanroom HVAC systems are inherently energy-intensive, as they are required to maintain precise control over both temperature and humidity within stringent limits.
Ravindran S   +4 more
doaj   +1 more source

BrainyEdge: An AI-enabled framework for IoT edge computing

open access: yesICT Express, 2023
Along with the proliferation of the Internet of Things (IoT) and the surge in the use of artificial intelligence (AI), Edge Computing has proved considerable success in reducing latency, network traffic consumption, and security risks. The convergence of
Kim-Hung Le   +2 more
doaj   +1 more source

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