Results 41 to 50 of about 2,114,184 (246)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Resource-Efficient Collaborative Training and Inference of Foundation Models in Edge-AI

The convergence of Edge Artificial Intelligence (Edge-AI) and foundation models marks a transformative paradigm shift in the design of intelligent systems.
Songyuan Li (21053258)
core   +6 more sources

CADSA: Content-Aware Dynamic Sparse Attention for Lightweight and Energy-Efficient Edge AI with Sub-Quadratic Complexity

Iraqi Journal for Computers and Informatics
This paper presents CADSA, a content-aware dynamic sparse attention framework that lowers the quadratic complexity of self-attention to sub-quadratic for lightweight edge AI deployment.
Abdullah Ghanim Jaber, Abeer Ahmed Ali, Ibrahim Alshammari, Saad Al-Dakheel, Ali A.Mahmood, Mohammed Jamal Salim   +5 more
doaj   +1 more source

A Lightweight Implementation of a Reduced-Depth SqueezeNet CNN on the Versal Platform for Edge Computing Applications [PDF]

پژوهش‌های نظری و کاربردی هوش ماشینی
In recent years, deep neural networks have been widely adopted in computer vision applications. However, deploying these networks on portable and edge devices faces serious challenges due to limited computational resources, memory capacity, and power ...
Zahra Ghasemi, Atefeh Salimi Shahraki, Mahdi Abbasi, Mohammad Lali Dastjerdi   +3 more
doaj   +1 more source

AI strategy to execution

, 2023
In this book, we discuss the “strategy to the execution gap” a leader of an organization encounters while adopting Artificial Intelligence (AI) in that organization.
Thoppan Mohanchandralal, Sudaman, Kumar, Dinesh U, Bradshaw, Anthony, Grumiau, Christopher   +3 more
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Urban AI Guide

, 2023
The URBAN AI GUIDE aids city leaders and urban technologists (academic, public, private, and community-focused) in better understanding how artificial intelligence operates in urban contexts.
Narvaez Zertuche, Laura, Beroche, Hubert, Popelka, Sarah   +2 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

AI Services-Oriented Dynamic Computing Resource Scheduling Algorithm Based on Distributed Data Parallelism in Edge Computing Network of Smart Grid

Future Internet
Massive computational resources are required by a booming number of artificial intelligence (AI) services in the communication network of the smart grid.
Jing Zou, Peizhe Xin, Chang Wang, Heli Zhang, Lei Wei, Ying Wang   +5 more
doaj   +1 more source