Results 201 to 210 of about 898,897 (299)

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

Modeling LTE-advanced cell capacity estimation using packet bundling and carrier aggregation. [PDF]

PeerJ Comput Sci
Senapati R.
europepmc   +1 more source

Boundary-Condition Quantum Mechanics IV_d: Bundle formation, graph–Darwinism, and inertial rigidity from shared edges

Peter Mark Ferguson
openalex   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

Advanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen, Jiahui Lai, Qiongjiao Zeng, Liangbin Zhou, Boguang Yang, Bin Zhang, Min Wang, Jiajing Zhou, Kieran Lau, Khoon S. Lim, Zhong Alan Li, Rocky S. Tuan   +11 more
wiley   +1 more source

Compositional neurosymbolic representations enable efficient active exploration. [PDF]

Nat Commun
Furlong PM, Dumont NS, Antonova R, Orchard J, Eliasmith C.   +4 more
europepmc   +1 more source

Revealing urban–rural migration corridors through edge-path bundling of historical census data in Bulgaria

Piet Gerrits, Guy Solomon, Anahid Basiri, Mustafa Erdem Kabadayı   +3 more
openalex   +1 more source

Adaptive Network Stabilization Despite Profound Structural Reorganization in Human Organotypic Cultures

Advanced Science, EarlyView.
Adult human organotypic cortical slices undergo marked neuronal loss, laminar disruption, and glial activation, yet their network activity progressively stabilizes after a variable period. Electrophysiology, longitudinal calcium imaging, and quantitative histology show that structurally remodeled human circuits show adaptive capacity resulting in ...
Estilla Zsófia Tóth, Rebeka Stelcz, Réka Bod, Ábel Petik, Eszter Juhász, Kinga Tóth, Liza Szalai, Nour Essam, Fanni Somogyi, Beatrix Kovács, Amirmahdi Mojtahedzadeh, Attila György Bagó, Loránd Erőss, Péter Orbay, Johanna Petra Szabó, Dániel Fabó, Boglárka Hajnal, Bence Rácz, Daniel Hillier, István Ulbert, Lucia Wittner   +20 more
wiley   +1 more source

<i>Arabidopsis</i> kinesins KCH3 and KCH7 promote root gravitropism through actin bundling in the stele. [PDF]

Proc Natl Acad Sci U S A
Niu Y, Chen S, Deng Z, Du J, Zhou Y, Fan N, Zhou D, Niu Y, Yang Y, An L, Chen S, Xiang Y, Chen H, Qian D.   +13 more
europepmc   +1 more source

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

Advanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore, Naomi King, Aruã Clayton Da Silva, Clare Howarth, Jason Berwick, Thomas E. Paterson, Ivan R. Minev   +6 more
wiley   +1 more source

A critical role for the fascin family of actin bundling proteins in axon development, brain wiring and function. [PDF]

Mol Cell Neurosci
Hardin KR, Penas AB, Joubert S, Ye C, Myers KR, Zheng JQ.   +5 more
europepmc   +1 more source