Results 41 to 50 of about 985,377 (253)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

When Mobile Blockchain Meets Edge Computing

open access: yes, 2018
Blockchain, as the backbone technology of the current popular Bitcoin digital currency, has become a promising decentralized data management framework.
Han, Zhu   +4 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

A survey on edge computing offloading

open access: yesDianxin kexue, 2019
Edge computing integrate the computing,storage and other resources on the edge of the network into a unified user service platform.According to the principle of nearest service,the network edge node task request is timely and correspondingly processed ...
Youkang ZHU   +3 more
doaj   +2 more sources

Neuro-memristive Circuits for Edge Computing: A review

open access: yes, 2018
The volume, veracity, variability, and velocity of data produced from the ever-increasing network of sensors connected to Internet pose challenges for power management, scalability, and sustainability of cloud computing infrastructure.
Chua, Leon O.   +2 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Spatio-temporal Edge Service Placement: A Bandit Learning Approach

open access: yes, 2018
Shared edge computing platforms deployed at the radio access network are expected to significantly improve quality of service delivered by Application Service Providers (ASPs) in a flexible and economic way.
Chen, Lixing   +3 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Engineering a QoS Provider Mechanism for Edge Computing with Deep Reinforcement Learning

open access: yes, 2019
With the development of new system solutions that integrate traditional cloud computing with the edge/fog computing paradigm, dynamic optimization of service execution has become a challenge due to the edge computing resources being more distributed and ...
Carpio, Francisco   +3 more
core   +1 more source

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