Results 51 to 60 of about 985,377 (253)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Bearing thinking of edge computing based on NFV

open access: yesDianxin kexue, 2018
Aiming at introducing edge computing into operator’s network,a bearing and deployment thinking based on NFV was presented.Firstly,the industry development trends of edge computing were introduced.Then the concept,service scenarios and special ...
Yujia LUO, Liang OU, Hong TANG
doaj   +2 more sources

An Overview on Edge Computing Research

open access: yesIEEE Access, 2020
With the rapid development of the Internet of Everything (IoE), the number of smart devices connected to the Internet is increasing, resulting in large-scale data, which has caused problems such as bandwidth load, slow response speed, poor security, and ...
Keyan Cao   +3 more
doaj   +1 more source

Software-Defined Heterogeneous Edge Computing Network Resource Scheduling Based on Reinforcement Learning

open access: yesApplied Sciences, 2022
With the rapid development of wireless networks, wireless edge computing networks have been widely considered. The heterogeneous characteristics of the 6G edge computing network bring new challenges to network resource scheduling.
Yaofang Li, Bin Wu
doaj   +1 more source

Optimal Pricing-Based Edge Computing Resource Management in Mobile Blockchain

open access: yes, 2017
As the core issue of blockchain, the mining requires solving a proof-of-work puzzle, which is resource expensive to implement in mobile devices due to high computing power needed.
Feng, Shaohan   +4 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Cloud native based edge computing: vision and challenges

open access: yes物联网学报, 2021
Cloud native computing, featured by low-cost container technology, well fits edge computing.It was proposed to apply cloud native computing to make edge computing resource management and control transparent to application development and operation ...
Deze ZENG   +3 more
doaj   +2 more sources

Data Security and Privacy-Preserving in Edge Computing Paradigm: Survey and Open Issues

open access: yesIEEE Access, 2018
With the explosive growth of Internet of Things devices and massive data produced at the edge of the network, the traditional centralized cloud computing model has come to a bottleneck due to the bandwidth limitation and resources constraint.
Jiale Zhang   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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