Results 101 to 110 of about 1,689,337 (289)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Simultaneous Sensing of Contact Force and Edge Orientation by Using Excitation From Fingernail

IEEE Access
In order to record and remotely transmit dexterous operations carried out by human finger pad, tactile sensors that capture finger pad contact information play a critical role.
Shoha Kon, Keigo Ushiyama, Izumi Mizoguchi, Hiroyuki Kajimoto   +3 more
doaj   +1 more source

Edge mode velocities in the quantum Hall effect from a dc measurement

New Journal of Physics, 2015
Because of the bulk gap, low energy physics in the quantum Hall effect is confined to the edges of the 2D electron liquid. The velocities of edge modes are key parameters of edge physics.
P T Zucker, D E Feldman
doaj   +1 more source

Edge reconstruction in the $\nu=2/3$ fractional quantum Hall state

, 2013
The edge structure of the $\nu=2/3$ fractional quantum Hall state has been studied for several decades but recent experiments, exhibiting upstream neutral mode(s), a plateau at a Hall conductance of $\frac{1}{3}( e^2/h)$ through a quantum point contact ...
Gefen, Yuval, Meir, Yigal, Wang, Jianhui
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Solution of contact pressure between robot edge with soft covering and human body surface considering nonlinear elasticity

Nihon Kikai Gakkai ronbunshu
In building a human-robot cooperative system, it is an important issue to reduce the harm caused by contact with the robot. A protective measure for a robot with a sharp and highly rigid surface is to smoothen the surface shape and reduce the rigidity in
Yusuke MORITA, Yoji YAMADA
doaj   +1 more source

Edge-Contact MoS₂ Transistors Fabricated Using Thermal Scanning Probe Lithography. [PDF]

ACS Appl Mater Interfaces, 2022
Conde-Rubio A, Liu X, Boero G, Brugger J.   +3 more
europepmc   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source