Results 71 to 80 of about 1,230,227 (332)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Color Invariant Edge Detection [PDF]

open access: yes, 1999
Segmentation based on color, instead of intensity only, pro- vides an easier distinction between materials, on the condition that ro- bustness against irrelevant parameters is achieved, such as illumination source, shadows, geometry and camera sensitivities.
Geusebroek, J.-M.   +5 more
openaire   +2 more sources

SalProp: Salient object proposals via aggregated edge cues

open access: yes, 2017
In this paper, we propose a novel object proposal generation scheme by formulating a graph-based salient edge classification framework that utilizes the edge context.
Lall, Brejesh   +2 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Moving-edge detection via heat flow analogy

open access: yes, 2011
In this paper, a new and automatic moving-edge detection algorithm is proposed, based on using the heat flow analogy. This algorithm starts with anisotropic heat diffusion in the spatial domain, to remove noise and sharpen region boundaries for the ...
Direkoglu, Cem, Nixon, Mark
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

THE FUSION OF EDGE DETECTION AND MATHEMATICAL MORPHOLOGY ALGORITHM FOR SHAPE BOUNDARY RECOGNITION

open access: yesJournal of ICT, 2016
Edge detection is important in image analysis to form the shape of an object. Edge is the boundary between different textures, which helps with object segmentation and recognition. Currently, several edge detection techniques are able to identify objects
Mahmod Othman   +4 more
doaj  

Analysis of Neural Networks for Edge Detection [PDF]

open access: yes, 2002
This paper illustrates a novel method to analyze artificial neural networks so as to gain insight into their internal functionality. To this purpose, the elements of a feedforward-backpropagation neural network, that has been trained to detect edges in ...
Slump, Kees   +2 more
core   +2 more sources

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