Results 81 to 90 of about 2,712,541 (299)

Classical Solution and Edge Effect in the Problem of Stability of an Axially Compressed Cylindrical Shell

Communications, 2020
The classical solution for critical stresses in the problem of stability of a circular longitudinally compressed cylindrical shell consists of two terms, reflecting the ability of the shell to resist buckling due to bending and membrane deformations ...
Guyk A. Manuylov, Sergey B. Kosytsyn, Maksim M. Begichev   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Gate-controlled transmission of quantum Hall edge states in bilayer graphene

, 2018
The edge states of the quantum Hall and fractional quantum Hall effect of a two-dimensional electron gas provide key access to the excitations of the bulk. Here we demonstrate controlled transmission of edge states in bilayer graphene.
Li, Jing, Taniguchi, Takashi, Watanabe, Kenji, Wen, Hua, Zhu, Jun   +4 more
core   +1 more source

Assessment of the Variation in Faunistic Parameters of Mosquitoes (Culicidae: Diptera) Across Different Forest Gradients in the Tijuca National Park Area, Rio de Janeiro, Brazil

Diversity
The assessment of mosquito diversity in remnants of the Atlantic Forest, which are considered biodiversity hotspots, is crucial for studying patterns of behavior and adaptation, performing environmental monitoring, and public health.
Nilton Henrique Fonseca do Nascimento, Paulo José Leite, Júlia dos Santos Silva, Hélcio Reinaldo Gil-Santana, Roger Pimentel Barbosa, Cecilia Ferreira de Mello, Jeronimo Alencar   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Manifestation of the bulk phase transition in the edge energy spectrum in a two dimensional bilayer electron system

, 2004
We use a quasi-Corbino sample geometry with independent contacts to different edge states in the quantum Hall effect regime to investigate the edge energy spectrum of a bilayer electron system at total filling factor $\nu=2$. By analyzing non-linear $I-V$
A. C. Gossard, A. Lorke, A. Sawada, A. Wixforth, A. Würtz, D. B. Chklovskii, D. C. Dixon, E. V. Deviatov, G. Müller, G. Müller, J. J. Koning, K. L. Campman, M. Büttiker, M. Hartung, M. Yu. Melnikov, R. J. Haug, S. Das Sarma, S. V. Iordanski, T. Jungwirth, V. Pellegrini, V. S. Khrapai, V. T. Dolgopolov   +21 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source