Results 81 to 90 of about 547,583 (266)
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Structural Mechanics of Engineering Constructions and BuildingsThe problem of strength analysis of a multi-modulus strip, in contradiction to the existing standpoint of essential nonlinearity, may be formulated as a linear problem for a two-layer strip.
Evgeniy M. Zveryaev
doaj +1 more source
Agriculture, 2019 In crop modeling and yield predictions, the heterogeneity of agricultural landscapes is usually not accounted for. This heterogeneity often arises from landscape elements like forests, hedges, or single trees and shrubs that cast shadows.
Martin Schmidt +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Methods to Detect Edge Effected Reductions in Fire Frequency in Simulated Forest Landscapes
ISPRS International Journal of Geo-Information, 2019 Reductions in fire frequency (RFF) are known to occur in the area adjacent to the rigid-boundary of simulated forest landscapes. Few studies, however, have removed those edge effected regions (EERs), and many others may, thus, have misinterpreted their ...
Xinyuan Wei, Chris P. S. Larsen
doaj +1 more source
A Normalization Protocol Reduces Edge Effect in High-Throughput Analyses of Hydroxyurea Hypersensitivity in Fission Yeast. [PDF]
Biomedicines, 2023 Lam UT +5 more
europepmc +1 more source
American Journal of Physics, 2007 We show that the baking of potato wedges constitutes a crunchy example of edge effects, which are usually demonstrated in electrostatics. A simple model of the diffusive transport of water vapor around the potato wedges shows that the water vapor flux diverges at the sharp edges in analogy with its electrostatic counterpart.
openaire +2 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Metrological Comparison of Available Methods to Correct Edge-Effect Local Plasticity in Instrumented Indentation Test. [PDF]
Materials (Basel), 2023 Kholkhujaev J +3 more
europepmc +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source