Results 91 to 100 of about 2,712,541 (299)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Optically exciting a magnetic memory - A feasibility study [PDF]

open access: yes, 1969
Rare earth iron garnets were used in experiments to determine the feasibility of optically pumping a magnetic material to effect the switching process.
Grismore, F. L., Rhodes, J. E.
core   +1 more source

Edge and Bulk Transport in the Mixed State of a Type-II Superconductor

open access: yes, 2001
By comparing the voltage-current (V-I) curves obtained before and after cutting a sample of 2H-NbSe2, we separate the bulk and edge contributions to the transport current at various dissipation levels and derive their respective V- I curves and critical ...
C. P. Bean   +34 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Epifitismo vascular em sítios de borda e interior em Floresta Estacional Semidecidual no Sudeste do Brasil

open access: yesHoehnea
As epífitas têm papel fundamental como indicadores ambientais e podem refletir o grau de preservação local. Esta pesquisa foi desenvolvida na Floresta Nacional de Ipanema, São Paulo, Brasil e objetivou caracterizar a comunidade epifítica vascular ...
Fernando Antonio Bataghin   +2 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Edge state modulation by mean viscosity gradients

open access: yes, 2017
Motivated by the relevance of edge state solutions as mediators of transition, we use direct numerical simulations to study the effect of spatially non-uniform viscosity on their energy and stability in minimal channel flows.
Bagheri, Shervin   +2 more
core   +1 more source

Evaluation of Edge Effects and Recreation on Plant Composition and Species Richness and Diversity (Case Study: the Noor Forest Park- Mazandaran Province) [PDF]

open access: yesبوم‌شناسی جنگل‌های ایران
Extended Abstract Background: It is essential to investigate the depth, strength, and main mechanisms of edge effects and recreational activities to preserve species diversity in forest ecosystems. This study aimed to evaluate edge effects and recreation
Rohollah Rostami   +4 more
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

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