Results 91 to 100 of about 5,151,122 (293)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Distribution of the edge features on TB simulations.
a, and b, are distributions of the raw edge features: time and genetic distance. c, and d, are distributions of the edge features processed by an ArcSinh transformation and a z-score normalization. (TIFF)
Mattia Prosperi (132270) +4 more
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Shadow edge detection using geometric and photometric features
, 2009 The detection of shadow and shading edges is a first step towards reducing the imaging effects that are caused by interactions of the light source with surfaces that are in the scene.
Gijsenij, A. +3 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
A Fast Algorithm for Intra-Frame Versatile Video Coding Based on Edge Features. [PDF]
Sensors (Basel), 2023 Zhao S, Shang X, Wang G, Zhao H.
europepmc +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Learnable edge detectors can make deep convolutional neural networks more robust.
PLoS ONEDeep convolutional neural networks (DCNNs) are vulnerable to examples with small perturbations. Improving DCNNs' robustness is of great significance to the safety-critical applications, such as autonomous driving and industry automation.
Jin Ding +6 more
doaj +1 more source
Semi-supervised nuclei segmentation based on multi-edge features fusion attention network. [PDF]
PLoS One, 2023 Li H, Zhong J, Lin L, Chen Y, Shi P.
europepmc +1 more source