Results 111 to 120 of about 5,151,122 (293)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Map of property of Kline Realty & Improvement Co.

open access: yes, 1910
Property map showing planned subdivision called River Edge ...

core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Oral History Interview with Jack Edge

open access: yes
The National Museum of the Pacific War presents a monologue with Jack Edge. Edge joined the Navy in 1941. He served aboard the USS Pelias (AS-14). They were conducting submarine overhauls at the Submarine Base where the ship was berthed during the ...
Edge, Jack
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Edge-guided multi-scale foreground attention network for change detection in high resolution remote sensing images

open access: yesInternational Journal of Applied Earth Observations and Geoinformation
Recently, deep learning methods have shown outstanding performance in remote sensing change detection (CD). To improve the accuracy of edge regions, researchers have introduced edge information as prior knowledge into CD methods.
Junjie Lin   +3 more
doaj   +1 more source

The AUC of distinct features of node biomarkers and edge biomarkers.

open access: yes, 2018
The AUC of distinct features of node biomarkers and edge biomarkers.
Jin Zhang (53297)   +6 more
core   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

A Method of Extracting Edge Feature of Mechanical Component Image

open access: yes工程科学与技术, 2008
:In order to effectively classify mechanical components in embedded system, a novel method was proposed to extract edge features of mechanical component images since mechanical components have comparatively obvious edge features.
doaj  

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

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